Fertility success with blastocyst transfer

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3.7 Minute

26-July-2024 Team Medicover Fertility

Overview on Success of Blastocyst Transfer

What is Blastocyst ?

In vitro fertilisation has been around for several decades. Many childless couples with fertility problems have been helped with this treatment and have been able to have children. Today, IVF is the most successful fertility treatment.

Researchers and scientists are constantly searching for better and new techniques to ensure a more successful pregnancy. They seek methods that will help the embryo to implant and grow into a healthy baby.

Over the years, new technologies have been introduced to IVF treatment, including the use of blastocysts. This advanced technique requires specialised infrastructure, advanced lab equipment, and skilled embryologists, but it significantly increases the chances of successful implantation.

Only larger fertility clinics like Medicover Fertility Clinic in India offer this treatment due to its specialised nature and proven success with no known side effects. However, only some embryologists or lab facilities have the capability to culture blastocysts.

WHAT IS A BLASTOCYST?

The blastocyst, which consists of about 200 cells, is formed through fertilisation in a lab setting. It is then transferred to the mother's uterus in a process called IVF transfer. After implantation in the uterine wall, the embryo can develop into a healthy baby.

DIFFERENT TYPES OF EMBRYO TRANSFERS

As a part of the IVF treatment, the egg and sperm are fertilised in the lab. After the egg and sperm are fertilised, the embryo is formed. The embryo is the egg that the sperm have successfully fertilised. The next stage of the IVF treatment involves transferring the embryo to the uterus of the female partner.

There are a few different types of embryo transfers that are used for IVF treatment. The embryo is kept in an incubator for a few days before it is transferred to the uterus.

3-Day transfer: The most common type of embryo transfer is the 3-day transfer, which most clinics practice.

Blastocyst transfer: The blastocyst transfer is conducted after 5 or 6 days when the embryo becomes a blastocyst.

Day 3 transfer:

Performed to avoid the risk of embryo failing to become a blastocyst.
If the embryo fails to become a blastocyst, it dies.

Medicover clinics:

Advanced infrastructure.
Highly skilled embryologists are confident in culturing embryos to blastocysts.
Success depends on the embryologist's expertise.

Embryo development:

Requires careful monitoring of changing nutritional needs.

BENEFITS OF BLASTOCYST

The blastocyst transfer has numerous benefits, which is why it is becoming increasingly popular. Larger hospitals and clinics prefer to use it as it helps to improve their reputation.

Receptive Uterus

Timing: Blastocyst transfer occurs on the 5th or 6th day after ovulation.
Receptivity: The uterus is more receptive on these days, increasing implantation likelihood.

Embryo Arrest

Day 3 vs. Day 5: Some embryos arrest between days 3 and 5.
Survival: Embryos past day 5 are more likely to survive and implant.

Better Embryo Selection

Development: Easier to identify healthier embryos by day 5 or 6.
Selection: Better embryo selection improves pregnancy success rates.

Reduced Risk of Multiple Pregnancies

Number of Embryos: Fewer embryos are transferred with blastocyst transfer, reducing the risk of multiples.
Discussion: The number of embryos transferred is decided with the doctor's advice.

Hatching Assistance

Technique: Assisted hatching helps embryos hatch before transfer.
Monitoring: Embryologist can assist and monitor hatching, improving implantation success.

Genetic Screening

Pre-implantation: It is easier to conduct genetic screening at the blastocyst stage.
Diagnosis: More accurate screening leads to better embryo selection.

Higher Implantation Rate

Statistics: Higher implantation and live birth rates with blastocyst transfer.
Preference: Larger fertility clinics prefer this technique for better success rates.

RISKS OF BLASTOCYST TRANSFER

While many benefits are associated with blastocyst transfer, people are curious to know the risks. The blastocyst transfer is gaining popularity in some fertility clinics due to its higher pregnancy rate. There are a few risks associated with the blastocyst transfer, which are:

Multiple Pregnancies

Parental View: Often welcomed by parents.
Doctor's Concern: Risks include low birth weight, pre-term birth, birth defects, miscarriage, and maternal health issues like high blood pressure.
Outcomes: Many successful cases with healthy babies.

Monozygotic Twins

Higher Risk: More likely with blastocyst transfer.
Definition: Identical twins from one embryo splitting into two.

Fewer Embryos

Challenges: Not all embryos reach the blastocyst stage.
Requirements: Skilled embryologist and proper lab conditions needed.
Risks: Embryos may arrest between days 3 to 5.

Lab Considerations

Equipment: Ensure the lab can culture embryos to blastocysts.
Strategy: Opt for day 3 transfer if unsure about lab capabilities; can combine with blastocyst transfer.

Case Study: Seema

Age: 42, with low ovarian reserve.
Approach: Transferred 3 embryos on day 3, cultured remaining to blastocysts.
Outcome: Successful pregnancy with one healthy blastocyst.

Conclusion

Success: The most important outcome, regardless of whether the 3-day embryo or blastocyst was successful.

WHY DO SOME FERTILITY CLINICS REFUSE BLASTOCYST TRANSFER?

It can be pretty frustrating for a couple when they have been trying IVF treatment and have not been successful so far. You ask your fertility clinic to do a blastocyst transfer because it has a higher success rate, but they refuse.

Culturing an embryo into a blastocyst is a delicate procedure that requires a skilled embryologist. Some clinics use external lab facilities for this process. In some cases, clinics opt for a day three transfer to absolve themselves of further responsibility for the embryos' survival.

However, as couples become more informed about fertility treatments, they can assess the quality of care offered by fertility clinics. Advanced fertility techniques are only available at a few reputable fertility clinics, such as Medicover Fertility Clinic.

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EXCELLENT LAB AT MEDICOVER

Medicover Fertility has a high-end lab equipped with the latest technology, modern equipment and facilities. The lab technicians are highly qualified and very experienced. The Medicover lab has full CCTV coverage, which allows patients to monitor what is being done with their eggs, sperm and embryos.

Medicover has a transparent relationship with its patients, who are apprised of every event and its happenings regarding their cases. The patients have no doubts, as every procedure is above board.

Blastocyst Transfer Procedure AT MEDICOVER

Medicover Fertility Clinic has improved its success rates for pregnancies ever since it introduced the option of using the Blastocysts transfer technique. A blastocyst transfer is not always suitable for IVF treatment.

Sometimes, doctors may feel that the embryos have a better chance of survival inside the mother's body than in the lab. In these cases, the embryo transfer is carried out on day three. The decision to culture an embryo to a blastocyst depends on the quality of the embryo and the way it responds to being in the culture dish.

Couples who have had multiple IVF failures with the day three transfer have a better chance of succeeding with a blastocyst transfer. Many couples come to Medicover after having tried IVF treatment in many places.

To some couples, Medicover Fertility Clinic is like a last resort. They are sure that if Medicover cannot help them conceive, no one can. The success rate of Medicover has preceded its reputation far and wide.

BEST FERTILITY TREATMENT AT MEDICOVER

Medicover offers the best fertility treatment options in north India. They have seven fertility clinics and have helped over 20 lac couples with fertility problems to have a baby. Medicover is part of a European brand and follows international standard treatment protocols.

Every Clinic is outfitted with modern infrastructure and caring staff. Medicover has a panel of in-house doctors. The doctors are highly qualified, internationally certified and very experienced in fertility treatment.

Frequently Asked Questions

Embryos with chromosomal abnormalities are usually arrested during the day 3 and 5 stages. It is very unusual for all the embryos to die unless the quality of your eggs is very poor. There could also be a problem with the lab facilities. It would be best to try treatment at a reputable clinic with good lab facilities.

A doctor decides it based on your case history. If you are not in agreement, you should take a second opinion.

The success rate with Blastocyst is better. You should consult with your doctor and decide based on their advice.

Yes, because it helps select the best embryos, which can increase the chances of pregnancy.

Staying healthy, following your doctor’s advice, managing stress, and sticking to the treatment plan can help.

If it doesn’t work, you can try another IVF cycle, consider using donor eggs or embryos, or explore other fertility treatments.

Doctors look at how well the embryos have grown and their appearance under a microscope to pick the best ones.

It's better because embryos that reach the blastocyst stage are stronger and have a higher chance of leading to pregnancy.

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