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Best Medications for Hyperthyroidism
Hyperthyroidism is a state in which the thyroid gland produces more than necessary thyroxine hormone. Possible symptoms include rapid heart rate, weight loss, night sweats, and anxiety. These symptoms need to be managed appropriately for quality of life to improve.
In this article, we examine the most commonly used medications for treating Hyperthyroidism, explaining how they work, their dosages, and the side effects of each so you know what to expect.
What is Hyperthyroidism?
Hyperthyroidism occurs when the gland located at the front of the neck becomes very active. It Regulates Metabolism: Considered the master of metabolism, the thyroid gland produces hormones like thyroxine (T4) and triiodothyronine(T3). These hormones control how your cells use food for energy. When produced in excessive amounts, hyperthyroidism can result.
Symptoms of Hyperthyroidism
The following are common symptoms of Hyperthyroidism:
- Rapid or irregular heartbeat
- Increased appetite but lost weight.
- Nervousness and irritability
- Shaking or Moving Hands and fingers
- Increased sweating
- Changes in menstrual patterns
- Increased sensitivity to heat
Importance of Treatment
If untreated, Hyperthyroidism can cause serious health problems like heart issues, weak and brittle bones ( osteoporosis), or a life-threatening drag-on called thyroid storm in which symptoms may become suddenly unhinged. Hence, Hyperthyroidism has to be treated effectively with medication and other treatments.
5 Best drugs for Hyperthyroidism
Many people, such as those with Hyperthyroidism and aggressive symptoms:
Methimazole (Tapazole)
How It Works
Frequency of drug use daily FDA Uses Methimazole (Tapazol) How works apparently inhibits synthesis of thyroid hormone by interfering with iodine-binding things in the gland, makes it block the secretion of TRH & TSH into blood thyroid hormones by preventing oxidation and organification of amino acid tyrosine consequent ethionamide compounds [1.3]: suppress production antibodies DLN/IRT, treat hyperthyroid effects large doses: *may inhibit peripheral conversion trinity iodothyronines actual mechanism action not fully understood Education points.
Dosage
The starting dose in adults is usually between 15mg and 60 mg a day, which can be taken in two or three doses. For ensuing maintenance, the dose may be lowered to 5-15 mg daily.
Side Effects
Common side effects include:
- Rash
- Nausea
- Headache
- Joint pain
Possible side effects include liver damage and neutropenia, a low white blood cell count making you prone to infections.
Propylthiouracil (PTU)
How It Works
Propylthiouracil also blocks the synthesis of thyroid hormone and inhibits its conversion into T3, the active form of thyroxine.
Dosage
The starting dose is typically 300-450 mg/day in divided doses. Preventive doses are 100-150 mg daily.
Side Effects
Common side effects include:
- Rash
- Nausea
- Loss of taste
- Joint pain
Hazards: severe side effects may cause liver toxicity and low white blood cell count.
Beta Blockers (Propranolol, Atenolol)
How They Work
Beta-blockers do not lower thyroid levels but are used to treat symptoms such as rapid heart rate, tremors and anxiety.
Dosage
The recording system, increased spacer, and individual beta-blocker doses are demonstrated in Figs. For instance, propranolol is usually administered 10-40 mg PO q6-8hr.
Side Effects
- Fatigue
- Dizziness
- Cold hands and feet
Radioactive Iodine
How It Works
It is a radioactive treatment that you take as a pill, and it goes to the thyroid gland, where this radioactivity will kill off all those overactive cells in your body.
Dosage
The amount of radioactive iodine that is given in any one treatment varies depending on the individual patients and their needs, as per doctor's prescription.
Side Effects
- Neck tenderness
- Dry mouth
- Transient elevation in thyroid hormones
Levothyroxine (Synthroid, Levoxyl)
How It Works
Levothyroxine is used to treat low thyroid hormone status, usually after radioactive iodine treatment or surgery.
Dosage
It is taken at a dose depending on an individual's needs, usually 50 to 100 mcg per day, and increased or decreased according to thyroid function tests.
Side Effects
- Headache
- Insomnia
- Weight changes
- Nervousness
Treatment of Hyperthyroidism With Drugs
Regular Monitoring
It would help if you got regular follow-up blood tests to make sure your thyroid hormone levels are within normal range. Based on these results, your healthcare provider will adjust the dosage of this medicine.
Lifestyle Adjustments
On top of medication, you should learn some lifestyle changes to counter hyperthyroidism such as:
- Eating a balanced diet
- Limiting the quantity of sugar and caffeine
- Relaxation techniques for coping with stress
When to See a Doctor?
Contact your healthcare provider right away if you have serious side effects from your medication or if symptoms do not get better.
Conclusion
Thankfully, Hyperthyroidism can be controlled with medication and lifestyle changes. The first-line medications for the treatment of Hyperthyroidism are methimazole, propylthiouracil (PTU), beta-blockers, radioactive iodine, and levothyroxine. Each has its pros, cons, doses, and side effects, so it is crucial to work alongside your provider to choose the best treatment plan.
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Book an AppointmentFrequently Asked Questions
The best medicines for hyperthyroidism depend on the individual's condition, but antithyroid drugs like methimazole (Tapazole) are commonly considered adequate. Methimazole helps to reduce the production of thyroid hormones and is often preferred because it is more efficacious and has fewer side effects compared to other treatments.
The first drug of choice for hyperthyroidism is usually methimazole. It is preferred over propylthiouracil (PTU) because it has a better side effect profile and is more effective at controlling thyroid hormone levels. However, PTU may be used in certain situations, such as during the first trimester of pregnancy.
General medication for hyperthyroidism include:
- Antithyroid Drugs: Methimazole and propylthiouracil (PTU) to reduce thyroid hormone production.
- Beta-blockers, Such as propranolol, manage symptoms like rapid heart rate, tremors, and anxiety.
- Radioactive Iodine Therapy: To reduce the thyroid gland by destroying overactive thyroid cells.
- Surgery: Thyroidectomy may be considered if other treatments are not effective or suitable.
The best medication for thyroid conditions depends on whether the issue is hyperthyroidism or hypothyroidism. For hyperthyroidism, methimazole is generally considered the best medication. For hypothyroidism, levothyroxine (Synthroid) is the standard and most effective treatment, providing synthetic thyroid hormone to normalize thyroid levels.
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