What is an ASO Test?

The ASO test measures the level of antistreptolysin antibodies in the bloodstream. These antibodies are produced by the immune system when it encounters streptolysin O toxin created by group A Streptococcus (GAS) bacteria. The production of these antibodies is a response to the GAS bacteria and helps the body fight against the infection.

Alternative Names: ASLO; ASO titer


Antistreptolysin O (ASO) Titer Test

  • The ASO titer test is used to measure the amount of antibodies produced by the body in response to a streptococcal infection.
  • Increased levels of ASO antibodies indicate a recent or ongoing streptococcal infection.
  • This test is valuable in the diagnosis of streptococcal infections like strep throat or scarlet fever.
  • By monitoring ASO levels, doctors can help prevent complications such as rheumatic fever or glomerulonephritis, which can occur if a streptococcal infection is not treated.
  • ASO titers are typically at their highest point around three to six weeks after the infection begins and then gradually decrease over time.

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What is the ASO Test Used for?

The ASO test, also known as the antistreptolysin O titer test, evaluates the body's antibodies in response to the group A Streptococcus (GAS) bacteria.

However, a strep infection may sometimes not show symptoms and could result in post-streptococcal complications. To prevent such complications, doctors perform the ASO test.


Why Do I Need an ASO Test?

If you show symptoms of post-streptococcal complications, such as

  • Rheumatic fever,
  • Glomerulonephritis, or bacterial endocarditis, your physician may suggest an ASO test.

Medical professionals use the antistreptolysin O titer test to evaluate your body's levels of antistreptolysin antibodies, which can help diagnose whether you are experiencing post-streptococcal complications.


What Happens During an ASO Test?

The healthcare provider may instruct you to fast for six hours before taking the ASO test. The procedure involves drawing blood from your inner arm vein with a fine needle, and the blood is then collected in a tube by the lab technician. The tube will be sent to the laboratory for examination.


What is the Usual Range of ASO?

The normal ASO test range for adults is below 200, while for children under five years, it is below 100. If your results exceed these levels, you may have a post-streptococcal complication.

Sometimes, even if your ASO test results are expected, your physician may recommend a follow-up test (second test) if you show symptoms of a post-streptococcal complication.


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What Does Abnormal Results Mean?

An abnormal or positive ASO titer test result indicates a recent strep infection, even if you did not experience symptoms.

Risks

Vein and artery sizes vary between individuals and even between different sides of the body. This can sometimes make it more difficult to draw blood from some people than others. The risks associated with blood draws are minimal but may include:

  • Excessive bleeding at the needle insertion site
  • Fainting or feeling lightheaded
  • Hematoma (blood collecting under the skin)
  • Infection (a slight risk anytime the skin is broken)

For ASO titer treatment, if the ASO test is positive, treatment may involve antibiotics or other medications to address any complications.


Is it Necessary to Fast Before an ASO Blood Test?

Before undergoing the antistreptolysin O titer test, the physician may advise you to fast for six hours to provide a blood sample.

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Frequently Asked Questions

1. Can the ASO test be used to diagnose strep throat?

The ASO test is not typically used to diagnose strep throat, as it is a blood test, not a throat swab test.

2. Can the ASO test be used to monitor the effectiveness of the streptococcal treatment?

The ASO test is not typically used to monitor the effectiveness of streptococcal treatment, as ASO levels may remain elevated even after successful treatment.

3. Are there any risks associated with the ASO test?

Although the risks associated with the ASO test are very rare, they can include bleeding or bruising at the site where the blood is drawn and infection.

4. Can ASO levels vary from person to person?

Yes, ASO levels can vary from person to person based on factors such as age, sex, and general health.

5. In Which disease is ASO titer positive?

ASO titers may not be increased in cases involving cutaneous or renal sequelae but are elevated in 85% of individuals with rheumatic fever.

6. Is ASO positive curable?

ASO treatment, in comparison to AAV treatment, does not result in a permanent cure and requires regular drug administration to the patient to keep the toxicity levels low.

7. What is the cost of an ASO test?

The cost of an ASO test is approximately Rs. 500/-

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