Cancer Antigen 125 (CA125) Test: Know Its purpose and Information
A CA-125 test is a blood test that detects the presence of a protein called CA-125 (cancer antigen 125) in the blood. CA-125 is considered a tumor marker and its elevated levels can indicate cancer. It's frequently used in ovarian cancer diagnosis and monitoring. The CA-125 blood test can also help track how well cancer treatments are working.
What is the Use of a CA-125 Test
The CA-125 test has several key uses, including:
- Tracking ovarian cancer treatment effectiveness and monitoring for recurrence.
- Assessing lumps in the pelvis to help determine if they are related to ovarian cancer.
- Screening for ovarian cancer in patients with a high risk or family history of the disease.
- The test can also detect elevated levels of CA-125 due to ovarian cysts, endometriosis, and other non-cancerous conditions, but it's not a standard screening for patients without risk factors.
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Book an AppointmentImportance of the CA-125 Blood Test
Your doctor may recommend a CA-125 blood test in various situations:
- During cancer treatment, to check if the therapy is effective.
- After treatment, to monitor for signs of cancer recurrence.
- If you're at high risk of developing ovarian cancer, due to a family history of ovarian or related cancers like breast or colorectal cancer.
In addition to monitoring ovarian cysts, the CA-125 test is also used alongside other markers for a more diagnosis.
What Happens During a CA-125 Blood Test
A healthcare provider will insert a needle into a vein in your arm to collect a blood sample. The test usually takes about five minutes, with minimal discomfort.
How to Prepare for the Test
No special preparation is required for the CA-125 blood test.
Is There Any Risk in the Test
While the CA-125 blood test is generally safe, you may experience slight discomfort or bruising at the needle insertion site. These effects typically fade quickly.
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Book an AppointmentWhat Do the Findings Imply
- Normal CA-125 Test Range: Generally, a CA-125 level below 35 U/mL is considered normal.
- High CA-125 Levels: Elevated CA-125 levels may indicate ovarian cancer or non-cancerous conditions like ovarian cysts, endometriosis, or uterine fibroids. Additional tests may be required to confirm the diagnosis.
- If you're undergoing treatment for ovarian cancer and your CA-125 levels drop, it suggests that the treatment is effective. Conversely, if levels remain high, it may indicate that the treatment is not working as expected, or that the cancer has recurred.
- Low CA-125 Levels: A normal CA-125 result doesn't always rule out cancer, particularly in the early stages. Additional diagnostic tests may be necessary.
Important Information About CA-125 Blood Test
The CA-125 test is particularly useful for monitoring epithelial ovarian cancer, the most common type. Some patients may also be tested for HE4 in addition to CA-125 to provide a more accurate assessment of treatment effectiveness and cancer recurrence.
Frequently Asked Questions
What is the CA-125 Test Full Form?
The full form of the CA-125 test is Cancer Antigen 125. It's a protein that can be elevated in certain types of cancer, particularly ovarian cancer.
What is the CA-125 Test Used For?
The CA-125 test is primarily used to monitor ovarian cancer treatment, detect recurrence, and sometimes to investigate other gynecological conditions like ovarian cysts or endometriosis.
What is the CA-125 normal range?
CA-125 levels in general are regarded normal to be between 0 and 35 units/mL, with levels above 35 units/mL considered high.
Who should be tested for CA-125?
If you have a high risk of ovarian cancer, your doctor may prescribe CA 125 testing. If the genes that enhance the risk of breast and ovarian cancer run in your family, your risk may be high.
Can CA-125 identify liver cancer?
Yes, CA-125 can identify liver cancer. Cancer antigen 125 levels are higher in individuals with acute and chronic liver illness, particularly those with cirrhotic ascites.
What is the cost of a CA-125 test?
The cost of a CA-125 test is approximately between Rs. 750 to Rs. 1400. However, it can vary from place to place.
