What are the uses of the lupus anticoagulant test?
The lupus anticoagulant test is primarily used to help diagnose antiphospholipid syndrome (APS), a condition that can cause blood clots in veins and arteries.
The lupus anticoagulant test is also used to investigate the cause of recurrent miscarriages. APS is associated with an increased risk of pregnancy complications, including miscarriage, stillbirth, and pre-eclampsia.
In addition, the lupus anticoagulant test may be ordered if a person has a history of unexplained blood clots or if they have a prolonged clotting time.
How is the lupus anticoagulant test done?
The lupus anticoagulant test is a blood test that is typically performed in a laboratory or clinic. The healthcare provider will insert a needle and draw blood from the arm vein.
In the laboratory, the blood sample will undergo a series of coagulation tests, such as the activated partial thromboplastin time (aPTT), dilute Russell viper venom time (dRVVT), and/or a clotting time assay.
Understanding test results
The results of the lupus anticoagulant test can be reported in different ways depending on the laboratory or clinic performing the test. However, a positive result typically means that there is lupus anticoagulant activity in the blood. A negative result means that there is no evidence of lupus anticoagulant activity.
It is important to note that a positive result does not necessarily mean that a person has antiphospholipid syndrome or is at increased risk for blood clots. Further testing and evaluation by a healthcare provider is necessary to determine the significance of a positive result.
In addition, a positive lupus anticoagulant test result can also be seen in other conditions, such as:
- Some infections
- Liver disease
- Certain medications, such as heparin,warfarin, and direct oral anticoagulants (DOACs).
Important information to know about this test
It is important to note that some medications, such as heparin, warfarin, and direct oral anticoagulants (DOACs), can interfere with the lupus anticoagulant test results. Therefore, it is important to inform your healthcare provider of any medications you are taking before undergoing the test.
