What is Amoebiasis or Amoebic Dysentery?

  • Amoebiasis, also known as amoebic dysentery, is an infection that affects the intestines. It is caused by a parasite called E. histolytica.
  • These parasites, known as entamoeba, can infect both humans and some animals. However, out of the six different entamoeba species that can infect the human intestine, only E. histolytica can cause disease.
  • Amoebae are single-celled organisms that can be found in moist environments like dirt, water, and other places. They have flowing extensions of their bodies called pseudopodia, which they use to move and feed.
  • Amoebae belongs to a group of germs called protozoa, which are microscopic, single-celled organisms.
  • E. histolytica resides in the intestines of infected individuals and can be passed out through their stools.
  • These parasites can survive for weeks or even months in soil, fertilizers, or water that has been contaminated with infected faeces.
  • If someone consumes contaminated food or drinks contaminated water, they can become sick and spread the disease to others.
  • In certain individuals, E. histolytica can enter the bloodstream from the gut and travel to other organs such as the liver, lungs, and possibly others.

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What are the Symptoms of Amoebiasis Disease?

The majority of people who have this parasite will not exhibit any symptoms. Those who do get ill might have minor or major signs. The mild kind of amoebiasis includes:

Sometimes, the parasite will spread from the intestines, resulting in a more severe infection, such as a liver abscess. After exposure, symptoms may appear from a few days to a few months, but often between two to four weeks.


When To See Doctor?

Consult the doctor immediately if anyone in your family has symptoms of amoebiasis, such as:

  • Diarrhea with blood or mucus,
  • Diarrhea that lasts longer than two weeks,
  • Abdominal pain,
  • fever,
  • Pain or tenderness below the ribs on the right side

Tell your doctor if you visited a part of the world where amoebiasis is common. Also, suppose your kid has diarrhoea and dehydration symptoms, including dry or sticky lips, less frequent urination, no tears while crying, dizziness, or sleepiness. In that case, you should get in touch with your doctor immediately.

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What are the Causes of Amoebiasis Disease?

A single-celled protozoan called E. histolytica often enters a person's system when they ingest cysts via food or water. It can also enter the body by coming in touch with faeces directly.

The parasite is a relatively inactive cyst that can survive for several months in the atmosphere or soil where they were deposited in faeces. Microscopic cysts can be detected in polluted water, fertilizer, or soil.

When preparing food, kitchen staff run the risk of spreading cysts. Additionally, transmission is possible during colonic irrigation, oral-anal sex, and anal intercourse.

Cysts that enter the body dwell in the digestive system, and the parasite's invasive, active form, known as a trophozoite, is then released. The parasites multiply in the gastrointestinal system before moving to the large intestine, and they can penetrate the colon or intestinal wall therein.


What are the Risk factors of Amoebiasis?

The risk factors usually include:

  • Traveling to or living in an area with a high incidence of amoebiasis, such as developing countries.
  • Poor sanitation
  • Lack of clean drinking water.
  • Eating or drinking contaminated food or water.
  • Close contact with an infected person.
  • Lack of personal hygiene.
  • Poor handwashing practices.
  • Having a weakened immune system.
  • Having a chronic disease such as diabetes or HIV.
  • Using antibiotics which can disrupt the balance of gut bacteria.
  • Consuming raw or undercooked meats, particularly pork.
  • Consuming raw fruits and vegetables that have been washed in contaminated water.
  • Consuming unbottled or tap water in high-risk areas
  • Working or living in crowded conditions.
  • Eating unhygienic street foods
  • Having a history of diarrhea or other intestinal infections
  • Consuming raw shellfish or other seafood
  • Consuming fermented or pickled foods
  • Working as a food handler or in a food-processing facility
  • Using recreational drugs that are taken orally
  • Having a history of poor nutrition

What are the Complications of Amoebic Dysentery

Amoebic liver abscesses are the most common amoebiasis complication, which is non-intestinal. These may result in symptoms like-

  • Fever
  • Pain in the right uppermost part of the abdomen
  • Jaundice.

Amoebiasis can, in rare circumstances, impact the respiratory system, leading to a collapsed lung. Empyema or a hepato-bronchial fistula can develop due to ruptured amoebic liver abscesses. Their typical symptoms include:

Although possible, amoebiasis can induce cardiac issues, which is often rare. Amoebiasis can, in very rare cases, lead to amoebic brain abscesses. These can cause the following symptoms:


What are the Prevention of Amoebic Dysentery

Amoebiasis can be prevented by practising good hygiene. Wash your hands thoroughly with soap and water before preparing food and after using the restroom. If you're visiting places where the infection is common, prepare and eat your food according to the following schedule:

  • Fruits and vegetables should be thoroughly washed before eating.
  • Use sealed bottles for soft drinks and bottled water.
  • To drink tap water, boil it for at least one minute before drinking.
  • Avoid using ice cubes or fountain drinks.
  • Avoid drinking unpasteurized milk, cheese, or other dairy products.
  • Avoid unhygienic food sold by street vendors.

How to Diagnose Amoebic Dysentery?

After understanding your current health and travel history, your doctor may detect amoebiasis. It can be challenging to diagnose because E. histolytica looks like other parasites, such as E. dispar. Your doctor may suggest stool examination and antigen testing to identify E. histolytica and rule out other potential infections.

Exams and Tests:

The following tests are done to check the presence of E. histolytica:

  • Most commonly, you might be asked to submit stool samples every few days for testing for the parasite. This is because there may be more amoebas than a single stool sample can identify, which might vary daily.
  • To find E. histolytica antigens, a stool test known as the ELISA (enzyme-linked immunosorbent assay) is frequently used.
  • To identify E. histolytica from other infections, a molecular polymerase chain reaction (PCR) test can be run using a blood sample or nose swab.
  • Your doctor may also request blood testing to detect whether the infection has spread from your intestines to another organ, such as your liver.
  • The parasites may disappear from your faeces once they spread outside the gut. To look for lesions in your liver, your doctor could recommend an ultrasound or CT scan.
  • Your doctor might need to do a needle aspiration if lesions develop to see whether the liver has any abscesses. Amoebiasis can have significant side effects, including liver abscesses.
  • Lastly, a colonoscopy may be required to determine whether the parasite is present in your large intestine (colon).

What is the Treatment for Amoebic Dysentery?

The treatment generally consists of the following:

  • If you experience symptoms, you should take a 10-day course of the antiamoebic medication metronidazole in tablet form.
  • If you need it, your doctor might recommend a nausea-controlling medication.
  • Antibiotics may be used to treat you if you don't display any symptoms.
  • The treatment must target the parasite and infected organs.
  • If the peritoneal tissues or colon have perforations, surgery might be required.
Antimicrobial Therapy Amoebic liver Adscess Intestinal Amoebiasis
Metronidazole 750-800mg three times daily for 5-10 days 750-800mg three times daily for 5-10 days
Tinidazole 2 g daily for 5 days 2 g daily for 3 days
Paromomycin - 25-35 mg/kg per day divided into three doses, for 7 days
Diloxanide Furoate - 500mg three times for 10 days

Consult your doctor before taking the above medicines.


Do's And Don'ts of Amoebiasis Disease?

Amoebiasis can also affect other organs, resulting in life-threatening consequences, including liver abscesses. To avoid problems and the spread of the illness, prompt identification, and treatment are essential. The following are many dos and don'ts that one might adhere to to prevent the harmful effects of amoebiasis.

Do's Don'ts
Wash your hands thoroughly with soap and water, especially after using the toilet. Consume food or water that may be contaminated with faecal matter.
Cook food thoroughly and consume it while it is still hot. Consume raw or undercooked meats.
Wash fruits and vegetables properly before eating them. Share personal items such as towels or toothbrushes with others.
Seek medical help if you have symptoms of amoebiasis. Self-medicate with over-the-counter medications or antibiotics.
Take all prescribed medications as directed by the doctor. Have sexual contact with someone with amoebiasis.

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Care at Medicover Hospitals

At Medicover Hospitals, we work with the greatest, most well-renowned General physicians & medical staff members to provide our patients with the best possible treatment while being compassionate and caring. With the active participation of healthcare professionals from several departments, each with their area of speciality, we treat amoebiasis holistically to provide complete care, improve recovery, and promote overall health. Our world-class medical professionals accurately identify the condition and provide therapeutic interventions.

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Frequently Asked Questions

1. What is amoebiasis?

Amoebiasis, also known as amoebic dysentery, is an infectious disease caused by the parasite Entamoeba histolytica. It primarily affects the intestines but can also spread to other organs like the liver.

2. How is amoebiasis transmitted?

Amoebiasis is typically transmitted through the ingestion of food or water contaminated with the cysts of the Entamoeba histolytica parasite. Additionally, it can spread by coming into contact with faeces directly.

3. What are the symptoms of amoebiasis?

Diarrhea, stomach pains, bloody stools, exhaustion, weight loss, and fever are just a few of the symptoms that can vary in severity from minor to severe. The infection may, in extreme circumstances, result in liver abscesses.

4. How is amoebiasis diagnosed?

Diagnosis often involves analyzing stool samples for the presence of the parasite or its cysts. In some cases, imaging studies like ultrasound or CT scans may be used to detect complications like liver abscesses.

5. Is amoebiasis a common disease?

Amoebiasis is common in areas with poor sanitation and contaminated water supplies. Travellers to such regions are also at risk. Not every parasite patient experiences symptoms, though.

6. How is amoebiasis treated?

Amoebiasis is usually treated with medications that target the parasite, such as metronidazole or tinidazole. Severe cases with complications like liver abscesses may require additional interventions.

. Can amoebiasis be prevented?

Yes, practising good hygiene, washing hands before meals, consuming clean water, and avoiding consuming food or drinks from unreliable sources can help prevent amoebiasis.

8. Can amoebiasis recur after treatment?

Recurrence is possible if the parasite isn't eliminated or if reinfection occurs. Completing the prescribed treatment and maintaining proper hygiene are crucial to preventing recurrence.

9. Is amoebiasis contagious?

Amoebiasis itself is not highly contagious. However, particularly in places with inadequate sanitation, the parasite can spread through contaminated hands, food, or water.

10. When should I seek medical attention for amoebiasis symptoms?

If you experience persistent symptoms like diarrhoea, abdominal pain, and bloody stools, especially after travelling to regions with poor sanitation, it's advisable to seek medical attention promptly.

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