Allopurinol is a drug that is used to lower elevated blood uric acid levels. It is marketed under the brand names Zyloprim and others. It is used to avoid gout, certain forms of kidney stones, and elevated uric acid levels that may occur as a result of chemotherapy. It's either taken orally or inserted into a vein.
Allopurinol is used for the treatment of gout and certain types of kidney stones. It is also used to prevent increased levels of uric acid in patients receiving chemotherapy for cancer. These patients may have increased levels of uric acid due to the release of uric acid from dying cancer cells. Allopurinol works by reducing the amount of uric acid produced by the body. Increased levels of uric acid may cause problems with the gut and kidneys.
Drug interactions can cause your drugs to function differently or put you at risk for severe side effects. Keep a list of all the medicines you use (including prescription and over-the-counter medications, as well as herbal remedies) and share it with your doctor and pharmacist. Without your doctor's permission, do not begin, stop, or alter the dosage of any medications.
Blood thinners (warfarin), capecitabine, and didanosine are some of the products that may interfere with this drug.
If you forgot to take any dose, take it as soon as you recall it. But if it is near the time of the next dose, skip the forgotten dose. Take your next dosage at regular intervals of time. Do not double the dose.
If you or someone has taken too much of this medicine and has serious symptoms such as passing out or trouble breathing, seek emergency medical help. Symptoms of overdose can include severe drowsiness, fainting, seizures, fast heartbeat.
note:
| Allopurinol | Colchicine |
|---|---|
| Also known Zyloprim | Also known Colcrys |
| Lowers uric acid levels in the blood, and prevents gout flare-ups. | Prevents and treats gout. |
| Used for treating Gout, High uric acid in cancer, Recurrent kidney stones | Used for - Gout, Gout prevention, Familial Mediterranean fever, Behcet's disease, and Inflammation of the heart. |
| Dosage forms- Injection, Pill | Dosage forms - Pill |
| Kidney stones can be formed while taking allopurinol, so you need to drink a lot of fluids to help prevent this. | Doses need to be changed if you have kidney or liver problems. |
Allopurinol is a drug that lowers uric acid levels in the blood. It can build up and cause small, sharp crystals to form in and around your joints if you generate too much uric acid or your kidneys do not flush it out enough. Gout and kidney stones are treated with allopurinol.
Side effects of taking allopurinol are
It will also assist you in remembering when you can take it. Once a day, allopurinol is normally taken. If your dose is greater than 300 mg, however, your doctor can encourage you to take it twice a day. It should then be taken in the morning and evening, after breakfast and dinner.
Adults and children aged 11 and up can take 600 to 800 milligrams (mg) per day, split into two or three doses over two to three days. Children aged 6 to 10 years old can take 300 mg once a day for 2 to 3 days.
Allopurinol use was linked to higher (not lower) modified risks of cardiovascular hospitalization (including coronary artery disease (CAD), hypertensive heart disease, heart failure, stroke, and other cardiovascular events) as compared to non-use.
Allopurinol can help reduce serum urate levels and alleviate gout symptoms without putting the kidneys at risk.
Allopurinol is linked to a minor but substantial decrease in blood pressure. This influence may be used to help hypertensive patients with hyperuricemia regulate their blood pressure.
Allopurinol (Zyloprim), a drug commonly used to avoid painful gout attacks, can cause liver damage in as little as a few days to weeks after starting treatment. If you are prescribed this medication, your doctor will also advise you to have routine blood tests to check your liver's health.
It may take up to two months for it to reach maximum effectiveness. It has no impact during a gout assault, but you can continue to take it on a daily basis even if this happens. Your blood levels of uric acid can rise for a short time within the first few weeks of taking allopurinol before falling.
Weight loss is more likely with allopurinol than weight gain. With allopurinol, patients experience weight loss, nausea, and a loss of appetite. Acute gout attacks, diarrhea, nausea, and skin rash are all possible side effects of allopurinol.
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