What is Ambroxol?

Ambroxol is a medication primarily used as a mucolytic agent, which means it helps to thin and loosen mucus in the respiratory tract, making it easier to cough up and clear from the airways.

It is commonly used in the treatment of respiratory conditions associated with excessive mucus production.

  • Ambroxol is a mucolytic agent that reduces sputum thickness, treating mucus secretion disorders.
  • Those who have a history of stomach ulcers need to be careful.

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Ambroxol Uses

Chronic Obstructive Pulmonary Disease (COPD):

Helps manage mucus hypersecretion and improves mucus clearance.

Bronchitis:

Effective in both acute and chronic bronchitis to reduce mucus viscosity and aid expectancy.

Asthma:

Used as an adjunct therapy to alleviate mucus-related symptoms.

Pneumonia:

Assists in the clearance of mucus in bacterial or viral pneumonia.

Cystic Fibrosis:

Aids in managing thick mucus secretions in the lungs.


Ambroxol Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Gastrointestinal side effects
  • Skin rash
  • itching
  • Infections
  • Allergies
  • Upset stomach
  • Dizziness
  • Weakness
  • Dry mouth
  • Indigestion
  • Numbness in throat
  • Numbness in mouth
  • Taste disturbances

Ambroxol Dosage

  • Adults: normal dosage from 30 mg (one tablet of Ambroxol) to 120 mg (4 tablets of Ambroxol) taken in 2 to 3 divided doses.
  • Children up to 2 years: half a teaspoonful Ambroxol syrup twice regular
  • Kids 2 to 5 years of age: half a teaspoon of Ambroxol syrup three times a day.
  • Children 5 years and older: one teaspoon of Ambroxol syrup 2-3 times a day.

Missed Dose

If you miss a dose, take it as soon as you remember. Do not double the dose to make up for the missed one. Consider setting an alarm or asking for reminders to avoid missing doses frequently. If you've missed several doses, contact your physician for guidance on adjusting your dosing schedule.

Overdose

Do not exceed the prescribed dosage to avoid poisoning or severe side effects. If you suspect an overdose, seek immediate medical help and bring the medication packaging for reference. Do not share your medication with others to prevent overdose. For further information, consult your doctor, or product packaging.


Precautions

  • Seek medical advice before using Ambroxol if you have symptoms of pneumonia, immune system issues, or lung conditions like COPD.
  • Notify healthcare professionals if you have serious gastric ulceration, liver or kidney issues, or allergies to ambroxol or bromhexine.
  • Avoid Ambroxol during the first trimester of pregnancy and while breastfeeding.
  • Always seek medical advice before use during pregnancy or breastfeeding.

How it works with ambroxol hydrochloride

Gaucher's disease results from GBA gene mutations, affecting glucocerebrosidase function in lysosomes, leading to glucocerebroside accumulation and symptoms like organ enlargement, bone issues, anemia, and neuropathy

It aids enzyme folding, promoting its lysosomal translocation to metabolize glucocerebroside, alleviating symptoms.


Warnings

  • If you have cough from long time, speak to the doctor
  • Don't take if you have asthma or asthma attacks
  • If you have liver issues speak to your doctor about it
  • If you have kidney issues consult
  • If you are having ulcers avoid taking this.
  • Avoid if you are pregnant or planning for a baby
  • Before breastfeeding consult your doctor

Ambroxol Storage

Store medicines at room temperature, away from heat, light, and moisture, and out of reach of children and pets. Avoid flushing drugs down the toilet or pouring them into drains. Contact your pharmacist or doctor for guidance on safe medication disposal.

Ambroxol Hydrochloride Syrup Expired

While adverse effects from a single dose of expired Ambroxol Hydrochloride Syrup are unlikely, consult your healthcare provider if you feel unwell. Expired medication may be ineffective and should not be used. For chronic conditions requiring regular medication, ensure timely renewal with your healthcare provider.

Interactions with other drugs

Inform your doctor or pharmacist about any medications, supplements, or herbal products you are taking. While extreme interactions are not known, caution is advised when taking antibiotics alongside ambroxol due to increased antibiotic penetration.

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Ambroxol vs Acetylcysteine

Ambroxol Acetylcysteine
Molar mass: 371028 g/mol Molar mass: 161951 g/mol
Formula: C13H18Br2N2O Formula: C5H9NO3S
Other names: Ambroxol hydrochloride Other names: N-acetylcysteine; N-acetyl-L-cysteine; NALC; NAC
Used to treat the respiratory related diseases associated with viscid Used to treat overdose of paracetamol, and to loosen the thick mucus

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Frequently Asked Questions

1. What is Ambroxol used for?

This drug is used for the symptomatic treatment of tracheobronchitis, an infection that induces tracheal (windpipe) and pulmonary airway inflammation. Ambroxol in this case relieves the patient from an excessive cough and thick sputum.

2. Is Ambroxol good for sore throat?

Yes, In some patients with acute sore throat, sucking lozenges containing 20 mg or 30 mg of ambroxol hydrochloride has positive results and beneficial pain-relieving effect, superior to that obtained by sucking a placebo lozenge.

3. Can I take Ambroxol without food?

The minimum dosage to be taken three times a day is 30 mg (one tablet). YES, these tablets can be taken with or without food.

4. Is ambroxol safe for pregnant women?

Ambroxol is generally considered safe during pregnancy, especially after the first trimester. However, it's essential to consult a healthcare professional before using any medication during pregnancy to weigh potential benefits against risks.

5. Which is better ambroxol vs bromhexine

Ambroxol and bromhexine are both mucolytic agents used to treat respiratory conditions, but individual responses may vary. Consult a healthcare professional to determine which medication is best suited for your specific condition and medical history.

6. How many times a day should one take Ambroxol?

Ambroxol is typically taken orally 2 to 3 times a day as prescribed by a healthcare professional. Always follow your doctor's instructions for dosage and frequency.

7. Can I use ambroxol for dry cough?

Ambroxol is primarily used for productive (wet) coughs as it helps to thin and loosen mucus in the airways. It is not typically recommended for dry coughs because these do not involve mucus production.

8. Who cannot take ambroxol?

Individuals who should avoid ambroxol include those with a known allergy to the drug. Caution is advised for people with severe liver or kidney impairment. Pregnant and breastfeeding women should consult their healthcare provider before use.

9. Is ambroxol safe for kidneys?

Ambroxol is generally safe for individuals with healthy kidneys when used as directed. However, those with severe kidney impairment should use it cautiously and under medical supervision.

10. Is ambroxol anti-asthma?

Ambroxol is not an anti-asthma medication. It is a mucolytic that helps clear mucus from the airways but does not treat the inflammation or bronchoconstriction associated with asthma. Asthma patients should use specific asthma medications prescribed by their doctor.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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