Berberine, an alkaloid derived from plants like the Berberis genus, serves as a bioactive compound and dye due to its yellow colour. With a history spanning thousands of years in Ayurvedic medicine, it effectively treats metabolic conditions such as:
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Get A Second OpinionSome of the common and major side effects of Berberine are:
The common side effects don’t need medical attention and will disappear as your body adjusts to the dosage. But if you are facing any serious or rare side effects, then immediately seek medical attention.
Berberine, available in capsule form, typically ranges from 1,000 to 1,500 mg daily, with a suggested starting dose gradually increasing to 1,500 mg, divided into three 500 mg doses throughout the day. Studies indicate that 1,500 mg of berberine, administered in three 500 mg doses, is comparable in efficacy to 1,500 mg of metformin or 4 mg of glibenclamide in reducing biomarkers of type 2 diabetes, according to both human and animal research.
Take the missed dose as soon as you remember it if you miss it. But if your next dose is almost here, skip the missing one and carry on according to your usual plan. Never take two doses to make up for a missing dose because doing so could raise the possibility of unfavourable side effects.
An accidental overdose of berberine tablets can have harmful effects on your body's functions and may lead to a medical emergency.
Berberine can lower blood sugar levels, posing a risk of hypoglycemia for diabetic individuals using insulin or other medications. Caution is advised for those with diabetes.
Berberine can slow the liver's removal of bilirubin, potentially causing brain issues, especially in infants with elevated bilirubin levels.
The drug can lower blood pressure. When using the medication in patients with low blood pressure, try to use caution.
Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly, the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
| Berberine | Metmorfin |
|---|---|
| Berberine is a bioactive compound that can be derived from a variety of plants, including the Berberis genus of shrubs. It is classified as an alkaloid in the scientific community. | Metformin is an oral diabetes drug that helps to control blood sugar levels. The medication is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. |
| It is a compound in various plants that includes goldenseal, braberry, Oregon grape and tree turmeric. Berberine supplements are used for the treatment of diabetes, obesity and inflammation. | Metformin is used with an appropriate diet and exercise program and possibly with other medicines to control high blood sugar levels. It is used for type 2 diabetic patients. |
Some of the common and major side effects of Berberine are:
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Most common side effects of Metformin are:
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Berberine is widely used to treat diabetes, high blood pressure, and high levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). It's also used to treat burns, canker sores, liver disease, and a variety of other ailments, but there's no clinical evidence to back up many of these claims.
In people with high cholesterol, taking berberine supplements on a daily basis tends to reduce total cholesterol, “bad” cholesterol, and triglycerides. It differs from today's traditional cholesterol medications in that it can be used to treat patients who have become immune to other cholesterol-lowering medications.
Berberine's sub-chronic toxicity has been linked to lung and liver damage by raising alanine aminotransferase (ALT) and aspartate aminotransferase (AST).
Berberine destroys the herpes simplex virus (HSV), which is commonly treated with acyclovir. Berberine helps with traumatic brain injury since it protects neurons in the brain and decreases inflammation (TBI).
Some of the common and major side effects of Berberine are:
Berberine can be useful as a weight-loss supplement as well. Two studies have looked at the impact on body weight so far. In a 12-week study of obese people, taking berberine 500 mg three times a day resulted in an overall weight loss of 5 pounds.
Berberine usage duration should be decided with a healthcare provider, considering health factors and goals. It's commonly used for short to medium-term periods, with long-term use needing careful monitoring for side effects.
In Ayurveda, berberine is recognized for its therapeutic properties and is derived from various plants like barberry and goldenseal. It's traditionally used to address various health conditions, including digestive issues, infections, and metabolic imbalances.
Berberine can generally be taken on an empty stomach, but it's advisable to follow manufacturer instructions or consult a healthcare professional for specific recommendations based on individual needs and sensitivities. Some people may experience gastrointestinal discomfort when taking berberine without food.
There's no scientific evidence to suggest that berberine causes skin darkening. However, individuals may experience changes in skin pigmentation due to other factors, and consulting a healthcare professional for personalized advice is recommended.
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