What is Bromhexine?

Bromhexine is a mucolytic agent that decreases sputum thickness. In order to enable the patient to breathe freely and deeply, it is used to treat conditions characterised by abnormal mucus secretion, such as the:

Common cold
Respiratory tract infections
Influenza

Because of the elevated risk of serious side effects, it should be used with caution in patients who have a history of gastric ulcers. Bromhexine improves mucus transport by lowering mucus viscosity and stimulating the ciliated epithelial layer (mucociliary clearance). Cough is relieved and the expectancy is made easier by secretolytic and secretomotor effects in the bronchial tract.

Bromhexine Uses

Bromhexine is a drug that aids the body's mucus-clearing processes in the respiratory tract. It is used to relieve chest congestion.
The medication belongs to a class of drugs called mucolytics, which break down mucus to make it easier to cough up.
As a result, to treat cough, this medication is added to cough syrups.
In order to prevent chest congestion, mucus in the respiratory tract should be expelled on a regular basis.
Bromhexine can help the body's natural mechanisms to remove inflammation by expelling mucus. Bromhexine is a mucolytic.

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Bromhexine Side effects

Some of the common and major side effects of Bromhexine are:

Irritation of ear
Allergic skin rash
Dizziness
Headache
Nausea
Vomiting
Diarrhea
Difficulty while breathing
Rash
Sweating
Throat infection

Bromhexine can cause some serious side effects and can lead to some serious health problems. If you are facing any of the above serious side effects, talk with your doctor immediately.

Precautions while taking Bromhexine

Before using Bromhexine talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other serious problems.
Before taking the drug talk with your doctor if you have any medical history such as:
Peptic ulceration
Asthma
Kidney disease
Stomach disease
Stomach ulcer
Abdominal pain
Severe hepatic or renal impairment

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How does Bromhexine work?

Bromhexine works by lowering mucous viscosity.
It will be accompanied by a rise in lysosomal activity.
The hydrolysis of acid mucopolysaccharide polymers will be accelerated if the lysosomal activity is increased.
This can lead to normal mucus viscosity.
The mucous viscosity in the bronchus would be higher if you have purulent bronchial inflammation.
The presence of a significant amount of DNA in the mucus is the basis for the mucus. Coughing can increase in the beginning as Bromhexine breaks down the mucous.

Missed dose

It is important to take the missed dose as soon as possible. If your next scheduled dose is approaching, it is best to skip the skipped dose. To make up for a missed dose, do not take extra medication.

Overdose

Overdose of a drug can be accidental. If you have taken more than the prescribed Bromhexine tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.

Warnings for some Serious Health Conditions

Liver Impairment:

Because of the increased risk of the patient's condition deteriorating, this drug should be used with caution in patients with a history of liver diseases. In certain cases, depending on the clinical condition, close monitoring of liver function tests, reasonable dosage changes, or replacement with a suitable alternative may be needed.

Gastric Ulceration:

Owing to the increased risk of the patient's condition worsening, this drug is not approved for use in patients with a confirmed history of gastric ulceration or any other gastrointestinal disorders. Any irregular signs should be reported to your doctor right away. Depending on the patient's clinical condition, appropriate dose changes or replacement with a suitable alternative may be required.

Pregnancy:

Pregnant women should not take this drug unless it is absolutely necessary. Before taking this drug, talk to your doctor about all of the complications and benefits.

Breastfeeding:

Bromhexine medications should not be used while breastfeeding. The medication can pass into the breast milk and can cause some serious side effects to the infants.

Storage

Direct contact with heat, air and light may damage your medicines. The exposure of medicine may cause some harmful effects.
The medicine must be kept in a safe place and out of children's reach.
Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).

Bromhexine vs Benadryl

Bromhexine	Benadryl
Bromhexine is a mucolytic agent that decreases sputum thickness. It is used to treat conditions characterised by abnormal mucus secretion, such as the common cold and respiratory tract infections.	Benadryl Syrup is used for cough care. Allergy symptoms such as runny nose, stuffy nose, sneezing, watery eyes, and stuffiness or coughing are relieved.
Bromhexine is a drug that aids the body's mucus-clearing processes in the respiratory tract. It is used to relieve chest congestion.	This medicine works by blocking a certain natural substance (known as histamine) that your body makes during an allergic reaction.
Some of the common and major side effects of Bromhexine are: Irritation of ear Allergic skin rash Dizziness Headache Nausea	Some of the common side effects of Benadryl are: Upset Stomach Sleepiness Headache Dizziness

Citations

Determination of bromhexine in cough–cold syrups by absorption spectrophotometry and multivariate calibration using partial least-squares and hybrid linear analyses. Application of a novel method of wavelength selection Research paperActivity of bromhexine and ambroxol, semi-synthetic derivatives of vasicine from the Indian shrub Adhatoda vasica, against Mycobacterium tuberculosis in vitro

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Frequently Asked Questions

1. What is Bromhexine used for?

Bromhexine is a mucolytic agent that decreases sputum thickness. It is used to treat conditions characterized by abnormal mucus secretion, such as the common cold, respiratory tract infections, and influenza, in order to enable the patient to breathe freely and deeply.

2. Is Bromhexine poisonous?

Bromhexine is a mucolytic agent that has a low level of side effects.

3. Is Bromhexine good for dry cough?

Guaifenesin and other expectorants are expected to help release and cough up mucus. Mucolytics, such as bromhexine, help to thin mucus in the airways by making coughing easier.

4. What are the side effects of Bromhexine?

Some of the common and major side effects of Bromhexine are:

Irritation of ear
Allergic skin rash
Dizziness
Headache
Nausea

5. How do you take Bromhexine?

Bromhexine is available as a tablet and a liquid. The tablets are normally taken three times a day, after meals, with plenty of liquid. Bromhexine liquid can be taken twice a day or four times a day. Nausea, rash, vomiting, diarrhea, and pain in the upper stomach are also possible side effects of bromhexine.

6. How long can you use Bromhexine?

Without medical advice, do not use it for more than 14 days. Bromhexine may be taken with or immediately after eating. Before using the syrup, give it a good shake. If you forget to take a dose, take it as soon as possible.

7. Is Bromhexine an expectorant?

Bromhexine is used to treat a condition in which the airways are clogged with thick phlegm. As a mucolytic, it aids in the relief of productive cough by thinning phlegm in the airways and making mucus removal easier.

8. Can Bromhexine be used with Ambroxol?

Yes, Ambroxol and Bromhexine can be used together as they both help in thinning mucus and easing its expulsion from the respiratory tract.

9. How should I take Bromhexine 4mg?

Take Bromhexine 4mg as directed by your doctor, usually 2-3 times a day with or without food.

10. Is Bromhexine safe for children?

Yes, Bromhexine can be used for children, but the dosage should be adjusted according to the child's age and weight as prescribed by a doctor.

11. Can I use Bromhexine during pregnancy?

Bromhexine should only be used during pregnancy if clearly needed and prescribed by a doctor.

Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.