What is Calcipotriol ?

Calcipotriol is a synthetic form of vitamin D that belongs to the anti-psoriatic drug class. It prevents the development of skin cells, which helps to regulate psoriatic disease. The medication is a synthetic derivative of Calcipotriol or vitamin D. It belongs to the group of drugs known as synthetic vitamin D3 derivatives. It works by reducing the rate at which skin cells are formed.


Calcipotriol Uses

  • Treats plaque psoriasis, the most common form of psoriasis.
  • Targets red, scaly patches on the skin.
  • Elbows, knees, scalp, and lower back.
  • Plaques can vary in size and itchiness.
  • Aims to eliminate these plaques quickly.

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Calcipotriol Side Effects

Common side effects of Calcipotriol may include:

Serious side effects are possible; consult your doctor if any severe reactions occur.


Important Precautions While Using Calcipotriol

Before using Calcipotriol:

  • Discuss allergies to Calcipotriol or related medications.
  • Inactive ingredients may cause allergic reactions.
  • Inform your doctor about all medications, including prescriptions, over-the-counter drugs, vitamins, supplements, and herbs.
  • Mention any medical history of kidney disease, liver disease or abdominal pain.

How to Use Calcipotriol

Calcipotriol is for topical use only:

  • Apply a thin layer to affected areas as directed by your doctor.
  • Ointment: Usually once or twice daily.
  • Cream or foam: Twice daily.
  • Wash hands after application unless treating hands.
  • Avoid applying on contaminated skin or covering with bandages.

Dosage Instructions for Calcipotriol 

Overdose

Vitamin D overdose can be severe:

Missed Dose

If you miss a dose:

  • Take it as soon as you remember.
  • Skip if nearing the next scheduled dose.
  • Do not double up on doses.

Storage

  • At room temperature (68°F to 77°F / 20°C to 25°C).
  • Protect from heat, light, and moisture.
  • Keep out of children's reach to prevent accidental ingestion.

Warnings for Serious Health Conditions

Pregnancy:

  • Topical treatments are generally safe, but avoid prolonged use of salicylic acid, Calcipotriol, topical steroids, or calcineurin inhibitors. UVB phototherapy is safer for severe psoriasis during pregnancy.

Breastfeeding:

  • Avoid applying ointment during breastfeeding.
  • Long-term use or application to large areas of skin should be discussed with your doctor while breastfeeding.

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Calcipotriol vs Alfacalcidol

Calcipotriol Alfacalcidol
Calcipotriol is a synthetic form of vitamin D that belongs to the anti-psoriatic drug class. It prevents the development of skin cells, which helps to regulate psoriatic disease. Alfacalcidol is a Vitamin D active metabolite that plays a key role in calcium balance and bone metabolism.
Calcipotriol is a drug that is used to treat plaque psoriasis, the most common form of psoriasis. Plaques are red scaly patches on your skin that form as a result of this disease. Alfacalcidol is a vitamin D supplement used to treat deficiency in conditions including hypocalcemia (low blood calcium levels), rickets (bone weakness), and others.
Some of the common and major side effects of Calcipotriol are:
  • Rash
  • Irritation in skin
  • Itching
  • Redness
Some of the common and major side effects of Alfacalcidol are:
  • Itching
  • Rash
  • Abdominal pain
  • Headache
  • Headache
  • Drowsiness

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Frequently Asked Questions

1. Is Calcipotriol a steroid?

Calcipotriol relieves inflamed, scaly areas by slowing the overproduction of skin cells. It's similar to vitamin D, which is required for good skin health. Calcipotriol is often used in conjunction with betamethasone, a steroid medication.

2. How long should I use Calcipotriol?

After a period of 4-8 weeks, a major therapeutic effect is normally observed. It is possible to repeat the treatment. Calcipotriol Ointment 50 micrograms/g once daily in conjunction with topical corticosteroids (e.g., steroid in the morning and Calcipotriol Ointment 50 micrograms/g in the evening) is safe and well tolerated.

3. How long does it take Calcipotriol to work?

Psoriasis is regulated by calcipotriene, but it is not cured by it. After two weeks, you may see some change in your condition, but it may take up to eight weeks to experience the full benefit of calcipotriene.

4. What are the side effects of Calcipotriol?

Some of the common and major side effects of Calcipotriol are:

  • Rash
  • Irritation in skin
  • Itching
  • Redness


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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