What is Canagliflozin ?

Canagliflozin is used in adults with type 2 diabetes mellitus to improve blood sugar control in conjunction with diet and exercise. The medication is also used to reduce the risk of death from

Individuals with heart disease and type 2 diabetes

Canagliflozin is also used to reduce the risk of last-stage kidney disease or death from heart problems in adults who have type 2 diabetes and kidney problems.


Uses of Canagliflozin

  • Canagliflozin is used in type 2 diabetes management alongside diet and exercise.
  • It helps prevent complications such as kidney damage, blindness, nerve issues, limb loss, and sexual dysfunction by controlling high blood sugar levels .
  • Canagliflozin reduces the risk of heart attack or stroke in individuals with diabetes and heart disease.
  • For those with type 2 diabetes and kidney disease, Canagliflozin 100 mg lowers the risk of dialysis, heart disease death, and hospitalisation for heart failure by enhancing sugar removal through the kidneys.

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How to use a Canagliflozin Tablet?

  • Before you take canagliflozin, and each time you get a refill, read the Medication Guide provided by your doctor.
  • If you have any worries, consult your doctor or pharmacist.
  • Take this medication orally as prescribed by your doctor, usually once a day before your first meal.
  • The dosage is determined by your medical condition, response to treatment, and any other medications you are taking.
  • To get the most out of this medication, take it on a regular basis.

Canagliflozin Side Effects

  • Bloating
  • Bloody or cloudy urine
  • Decreased frequency or amount of urine
  • Increased thirst
  • Indigestion
  • Itching
  • Loss of appetite
  • Lower back or side pain
  • Nausea
  • Redness
  • Dizziness
  • Drowsiness
  • Trouble breathing
  • Tiredness
  • Weakness
  • Vomiting
  • Weight gain

Precautions while taking Canagliflozin

  • Inform your doctor or pharmacist about any allergies to canagliflozin or other substances.
  • Discuss your medical history with your doctor or pharmacist, especially if you have kidney disease, dehydration, low blood pressure, heart failure, or mineral imbalances.
  • Be aware of symptoms like blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels.
  • Limit alcohol intake as it can increase the risk of low blood sugar and high ketone levels.
  • Stressful conditions may make blood sugar control more challenging, leading to high ketone levels, especially if eating is reduced.
  • Older adults may experience increased sensitivity to side effects such as dizziness, dehydration , and bone loss.
  • Consult your doctor before using this drug if you plan to become pregnant.
  • Consult your doctor regarding the passage of this medication into breast milk before breastfeeding.

Interactions of Canagliflozin

Many drugs can affect your blood sugar, making it more difficult to control. Before beginning, discontinuing, or changing any medication, consult your doctor about how the medication may affect your blood sugar. Check your levels of blood sugar on a regular basis and share the results with your doctor.

If you experience symptoms of high or low blood sugar, contact your doctor right away. Your diabetes medication, exercise program, or diet may need to be adjusted by your doctor.


Overdose

Overdose of a drug can be accidental. If you have taken more than the prescribed Pregabalin tablets, there is a chance of getting a harmful effect on your body’s functions. Overdose of this medicine can lead to some medical emergencies.

Missed Dose

If you forget to take any dose of this medicine, skip the missed dose and return to your regular dosing schedule. Do not double the dose.


Storage of Canagliflozin

The medicine should not come in direct contact with heat, air, or light and may damage your medicines. Exposure to medicine might cause some harmful effects or serious side effects. The medicine must be kept in a safe place and out of children’s reach.


Canagliflozin vs Dapagliflozin

Canagliflozin Dapagliflozin
Canagliflozin is used in adults with type 2 diabetes mellitus to improve blood sugar. Dapagliflozin is an oral diabetes medication that aids in blood sugar control.
It reduces blood sugar level by causing the kidneys to excrete more glucose in the urine. Dapagliflozin works by assisting the kidneys in removing glucose from the bloodstream.
Canagliflozin is used to control high blood sugar in people with type 2 diabetes in conjunction with a proper diet and exercise program Dapagliflozin is used in adults with type 2 diabetes mellitus, along with diet and exercise, to improve blood sugar control.

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Frequently Asked Questions

What is canagliflozin used for?

Canagliflozin is used to lower blood sugar levels in people with type 2 diabetes, along with diet and exercise and, in some cases, other medications (a condition in which blood sugar levels increase because the body does not produce or use insulin normally).

Does canagliflozin cause weight gain?

Canagliflozin has been associated with weight loss in some rare cases you might gain weight.

How long does it take for Canagliflozin to work?

Although steady-state levels are achieved in 4 to 5 days, clinical effectiveness with Invokana varies from person to person and may take longer due to your unique factors such as age, weight, additional medications you take, kidney or liverfunction, or other medical conditions.

Can you take canagliflozin with metformin?

To treat type 2 diabetes, a combination of canagliflozin and metformin is used in conjunction with a healthy diet and exercise. In patients with type 2 diabetes and heart or blood vessel disease, this medication is also used to reduce the risk of a heart attack, stroke, or death.

Does canagliflozin cause hypoglycemia?

Canagliflozin is generally well-tolerated, but it is associated with adverse events (AEs) related to the mechanism of action (GMOs, osmotic diuresis-, and volume depletion-related AEs). Canagliflozin has a low incidence of hypoglycemia in patients who are not taking insulin or a sulfonylurea.

Does canagliflozin cause edema?

If you have fever, unusual tiredness or weakness, or pain, tenderness, redness, or swelling between and around your anus and genitals, see your doctor right away. This medication may cause severe allergic reactions such as anaphylaxis or angioedema.

Is canagliflozin safe?

Canagliflozin is an effective diabetes medication with potential cardiovascular and renal benefits, as well as generally well-tolerated diabetes. It is considered safe.

Is canagliflozin safe in pregnancy?

In pregnant women, there is insufficient data to determine a drug-associated risk for major birth defects and miscarriage; animal data have shown adverse renal effects with administration during the renal development period, in the late second and third trimesters of human pregnancy.

Can canagliflozin cause kidney failure?

It can increase your risk of kidney damage

Can canagliflozin cause increased urination?

Yes, the side effects can lead to a change in the amount or frequency of urination.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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