What is Cetrorelix?

Cetrorelix, also known by its brand name CETROTIDE, is a prescription medication used to manage infertility. It belongs to a class of medicines called Gonadotropin Releasing Hormone Antagonists.

Usage: Cetrorelix is employed in women for controlled ovarian stimulation during fertility treatments. It works by blocking the hormone (gonadotropin-releasing hormone-GnRH), which prevents premature ovulation and allows eggs to develop properly. Typically, it is used in conjunction with another hormone (human chorionic gonadotropin-hCG) to facilitate pregnancy.

Cetrorelix Uses

Cetrorelix is used to manage infertility in women by preventing premature ovulation, allowing eggs to develop properly. It is often combined with human chorionic gonadotropin (hCG) to aid in pregnancy.

How to Use the Cetrorelix Kit?

Before starting Cetrorelix, read the Patient information Leaflet provided by your pharmacist. Consult your doctor or pharmacist for clarification on any doubts.

Instructions:

Shake the vial gently before use.
Inject the medication under the skin (subcutaneously) as directed by your doctor, typically once daily.
Administer the injection into the stomach area, at least one inch away from the belly button.
Rotate injection sites to minimize skin damage.
Follow your doctor's instructions on timing and duration of treatment.
Store and dispose of medical supplies properly.

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Cetrorelix Side Effects

Common side effects of Cetrorelix include nausea, headache, and pain/bruising at the injection site. Most users do not experience significant side effects.

Serious Side Effects:
- Ovarian hyperstimulation syndrome (OHSS) is a rare but serious complication that may occur during or after treatment.
- Seek immediate medical attention if you experience severe abdominal pain, swelling, nausea, vomiting, rapid weight gain, decreased urination, rashes, itching, difficulty breathing, dizziness, headache or redness.

Precautions To Be Taken

Before using Cetrorelix, inform your doctor or pharmacist if you are allergic to it or other GnRH products, or if you have any allergies. Discuss your medical history, especially any history of serious allergic reactions or kidney disease.

Surgical Considerations:
- Inform your healthcare provider about all medications and herbal products you are using before undergoing surgery.
Pregnancy and Breastfeeding:
- Avoid using Cetrorelix if you are pregnant or breastfeeding, as it may pose risks to the fetus or nursing infant. Consult your doctor for guidance.

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Serious interactions

Drug interactions can cause reactions and change the way your drugs work or increase your risk of serious side effects. Keep a check on all the medications you use including prescribed and non prescribed drugs and any herbal products) and share them with your doctor and pharmacist. Do not start, stop or change the dosage of any drug without your doctor's permission.

Dosage

Overdose

When someone has overdosed and has extreme signs such as passing out or respiratory problems

Do not share with anyone this drug.Do not share with anyone this drug.
Laboratory and/or diagnostic tests (such as cervical ultrasound, hormone levels) can be performed when you are using this drug. Keep all medical and laboratory appointments in place. For more info, contact your doctor.

Missed Dose

It is very important to follow the schedule. In case you miss any dose consult an expert.

Storage

Different products have different storage requirements. Please refer to the storage details printed on your package for the exact temperature range

Do not flush the medication in toilets, washrooms or drains.

For Adult: Dosage Forms & Strengths

Injectable solution

0.25mg
3mg

Infertility treatment

Single-dose regimen should be 3 mg SC, serum estradiol levels show appropriate stimulation response which is day 7; if hCG not administered within 4 days, continue dose at 0.25 mg/day until hCG administered

Multiple-dose regimen

0.25 mg SC two times a day, morning or evening of stimulation day 5 or morning of stimulation day 6; continue until hCG administered
For Pediatric use, it is not recommended

Citations

Comparison of different doses of gonadotropin-releasing hormone antagonist Cetrorelix during controlled ovarian hyperstimulation, ID:10.1016/S0015-0282(97)81407-0

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Frequently Asked Questions

1. What are the uses of Cetrorelix?

Cetrorelix is used in women for some fertility treatments (controlled ovarian stimulation). This medicine works by preventing eggs from being released too early (premature ovulation) by blocking the hormones (gonadotropin-releasing hormone-GnRH) that allows eggs to be released from the ovaries. This leads the growth time of eggs to increase properly. This drug is usually combined with another hormone (human chorionic gonadotropin-hCG) to help you get pregnant.

2. What are the side effects of Cetrorelix?

Extreme pain, Swelling in the lower abdominal (pelvic) region, Nausea, Vomiting, Sudden/fast weight gain, Decreased urination, Rashes, Itching, Difficulty in breathing, Dizziness, Headache, Redness.

3. What is the role of Cetrorelix in IVF?

Cetrorelix avoids premature LH surge that occurred elsewhere in the CC-FSH-cetrorelix protocol.basically it is used for IVF treatment.

4. What happens if you take cetrotide late?

Cetrotide 0.25 mg should be administered at 24 hours intervals of time. But if you forget to take Cetrotide 0.25 mg at the same time it will lead to no big problem to administer this dose at a different time of the same day.

5. What should be avoided while taking cetrorelix

Follow your doctor's orders for any limits on food, drinks, or operation.

6. What drugs will InfluenceCetrorelix (CETROTIDE)?

Many other drugs and medicine can interact with cetrorelix, including prescription and over-the-counter medicines, vitamins and some herbal products. Tell each of your health care professionals about all the medications you are taking now and any medicines you start or stop using.

7. How fast is Cetrotide working?

In women, Cetrotide delays LH-surgery and, subsequently, ovulation in a dose-dependent manner. FSH levels shall not be affected at doses used during managed ovarian stimulation. After a single 3 mg dose of Cetrotide®, a period of action of at least 4 days has been identified.

Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.