What is Desloratadine?
Desloratadine is a second-generation tricyclic antihistamine that functions as a potent H1 antagonist in the peripheral nervous system. It's loratadine’s active descarboethoxy metabolite (second-generation histamine). Since desloratadine does not readily reach the central nervous system, it has a long-lasting effect and does not cause drowsiness.
It is available as a tablet, a disintegrating tablet, or an oral syrup. Both forms are taken orally. Clarinex is a brand-name drug that contains desloratadine. It can also be obtained as a generic drug.
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Get A Second OpinionWhat are Desloratadine uses?
Desloratadine is used to treat hay fever and allergy symptoms in adults and children. These symptoms include:
- Sneezing
- Runny nose
- Swollen, itchy, weeping eyes
- Itching and rash associated with urticaria (hives; red, itchy raised areas of the skin).
Desloratadine Side Effects
Some of the common side effects of Desloratadine are:
- Sore throat
- Dry mouth
- Muscle pain
- Tiredness
- Sleepiness
- Menstrual pain
- Tiredness
- Sore throat
Some of the serious side effects of Desloratadine are:
- Skin rash
- Itching
- Hives
- Swelling of the lips, tongue or throat
Most people don't have significant side effects. If you notice any effects, contact your doctor immediately.
Precautions to Take Before Using Desloratadine
- Consult your doctor if you have allergies to Desloratadine or any other medications.
- Discuss any medical history, including kidney disease, liver disease, abdominal pain, or stomach ulcers, with your doctor.
- Be aware that Desloratadine products may contain inactive ingredients that could trigger severe allergic reactions or other problems.
How to take Desloratadine?
Take Desloratadine as advised by the doctor
- Available in three forms: pill, oral solution (liquid), and orally disintegrating tablet
- Taken once daily, with or without food
- Use a dropper or oral syringe to dose the solution
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Book an AppointmentDosage of Desloratadine:
| Dosage for | Adult Dosage (ages 18 and older) | Forms and Strengths |
|---|---|---|
| Seasonal Allergic Rhinitis | 5 mg tablet once a day | Generic: Desloratadine (oral tablet 5 mg) Brand: Clarinex (oral tablet 5 mg) |
| Perennial Allergic Rhinitis | 5 mg tablet once a day | Generic: Desloratadine (oral tablet 5 mg) Brand: Clarinex (oral tablet 5 mg) |
| Chronic Itching due to Hives (Idiopathic Urticaria) | 5 mg tablet once a day | Generic: Desloratadine (oral tablet 5 mg) Brand: Clarinex (oral tablet 5 mg) |
Missed Dose:
- If you miss a dose, take it as soon as you remember.
- If it's close to the time for your next dose, take only one dose. Do not double up to make up for missed doses, as it could be dangerous.
Overdose:
- Accidental overdose can occur if you take more than the prescribed amount of Desloratadine tablets.
- Overdose can lead to medical emergencies and harmful effects on the body's functions.
Interactions
Drug interactions can affect how medications work or increase the risk of serious side effects. Examples of drugs that may interact with Desloratadine include:
- Disopyramide
- Anticholinergics (such as atropine, belladonna alkaloids, and scopolamine)
- Certain blood pressure medications (like clonidine, guanadrel, and guanethidine)
- Digoxin
- Thyroid supplements
- Valproic acid
MAO inhibitors should not be used with Desloratadine due to the risk of serious, possibly fatal interactions. Avoid MAO inhibitors, and consult your doctor about the timing of Desloratadine use in relation to MAO inhibitors.
Warnings for some serious health conditions
Individuals with specific health conditions are more likely to experience the side effects. The health conditions include
- Liver diseases
- Kidney diseases
- Pregnancy
How to Store Desloratadine?
- Keep away from heat, air, and light exposure, as these factors can damage it.
- Keep the medicine in a safe place that is out of reach of children.
- Keep the drug at room temperature, ideally between 68ºF and 77ºF (20ºC and 25ºC).
Desloratadin vs Cetrizine
| Desloratadine | Cetirizine |
|---|---|
| Desloratadine is a second-generation tricyclic antihistamine that functions as a potent H1 antagonist in the peripheral nervous system. | Cetirizine tablets are an antihistamine that is used for relieving the allergy symptoms such as watery eyes, runny nose, itching eyes/ nose, hives and itching |
| Desloratadine is used to treat hay fever and allergy symptoms in adults and children, such as sneezing, runny nose, and swollen, itchy, weeping eyes. | Cetirizine does not prevent hives but it treats serious allergic reaction |
Some of the common side effects of Desloratadine are:
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Some of the common side effects of Stelara are:
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