What is Domperidone?
Domperidone is a medicine that belongs to a class of drugs known as dopamine receptor antagonists. Domperidone works by blocking dopamine receptors in the stomach and upper intestine. This action boosts the movement of food through the digestive system, easing symptoms like nausea, vomiting, bloating, and discomfort.
Uses of Domperidone
- Domperidone is used to treat gastrointestinal motility disorders like gastroparesis.
- It helps relieve symptoms such as nausea, vomiting, bloating, and discomfort.
- It works by increasing the movement of food through the digestive system.
- In some countries, it may also be used to alleviate symptoms of GERD, such as heartburn and regurgitation.
Domperidone Side Effects
- Swelling of face
- Swelling of hands and feet
- Difficulty in breathing
- Skin rash
- Convulsions
- Irregular heartbeat
- Disrupted menstrual cycle
- Breast pain and tenderness
- Dry mouth
- Chest pain
- Dizziness and fainting
- Extreme tiredness
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Get A Second OpinionPrecautions
- Take Domperidone before meals as directed by your doctor.
- Avoid alcohol while using Domperidone.
- Do not exceed seven days of Domperidone use without consulting your doctor.
- Avoid use in children under 12 years old or weighing less than 35 kg.
- Use caution in elderly patients over 65 years old; dosage adjustments may be needed.
- Use in pregnant women only if benefits outweigh risks; consult a doctor first.
- Avoid use in breastfeeding mothers due to potential adverse effects on the infant.
General Warnings
- Inform your doctor about all current medications, including herbs and supplements, before starting Domperidone.
- Inform your doctor if you develop watery diarrhea, a fever, or persistent stomach pain.
- Use Domperidone cautiously if you have a history of cardiovascular diseases; close monitoring may be necessary.
- Exercise extreme caution if you have electrolyte imbalances; regular monitoring of electrolyte levels is advised.
- Domperidone may affect prolactin levels, potentially disrupting menstrual cycles in women and causing breast-like growth in men.
- Use Domperidone for the shortest duration and at the lowest effective dose possible. Avoid self-administration.
Interactions
- Take before a meal, ideally 15-30 minutes beforehand.
- Discuss drug interactions with your doctor before starting any medication.
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Book an AppointmentDosage
- The specific dosage can vary based on individual circumstances and the condition being treated.
- The dosage of Domperidone typically ranges from 10 mg to 20 mg taken up to three times a day, usually before meals.
Missed Dose:
- If a dose is missed, take it as soon as remembered.
- If nearing the next scheduled dose, skip the missed one.
- Resume a regular dosing schedule; do not double up.
Overdose:
- If overdose symptoms like passing out occur, seek medical help.
- Never exceed the prescribed dosage.
Storage:
- Store at room temperature.
- Keep away from direct sunlight, heat, and moisture.
- Avoid storing it in the bathroom.
- Keep out of reach of children.
Domperidone vs Metoclopramide
| Domperidone | Metoclopramide |
| Domperidone 10 MG Tablet is an effective anti-emetic used for relieving nausea and vomiting | Metoclopramide is a medication that is used to treat stomach and esophageal issues. |
| Domperidone is used in the treatment of, nausea, indigestion, and vomiting. | It is commonly used to treat and prevent nausea and vomiting, to aid in stomach emptying in people with delayed stomach emptying, and to aid in the treatment of gastroesophageal reflux disease. It is also utilized in the treatment of migraine headaches. |
| It acts on the part of the brain that controls vomiting. It also acts on the upper digestive tract to increase stomach and intestine movement, allowing food to pass more easily through the stomach. | Metoclopramide works by inhibiting a naturally occurring substance (dopamine). It hastens stomach emptying and upper intestine movement. |
