Doxazosin, marketed under the brand name Cardura, among others, is a medication used to treat symptoms of an enlarged prostate and high blood pressure. However, it is a less favorable choice for high blood pressure. Doxazosin is taken orally.
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Book an Appointment| Doxazosin | Prazosin |
|---|---|
| Formula: C23H25N5O5 | Formula: C19H21N5O4 |
| Belongs to alpha-blockers. | An alpha-1 blocker |
| Used to treat high blood pressure alone or with other medications, and BPH. | Used to treat high blood pressure, enlarged prostate, and post-traumatic stress disorder (PTSD). |
| Trade Names: Cardura, Carduran, others | Brand Names:Minipress, Prazin, Prazo |
Doxazosin is used for treating high blood pressure alone or with other medications (hypertension). Lowering high blood pressure helps to avoid strokes, kidney complications, and heart attacks. Doxazosin is also used in men to relieve the effects of an enlarged prostate.
Take the first dose of doxazosin at bedtime to prevent injuries due to dizziness or fainting. It is possible to increase the dosage gradually. When your dosage is raised, take your first new dose at bedtime, unless otherwise instructed by your doctor. The dosage is dependent on your medical condition and therapy reaction.
What is, and how does, doxazosin mesylate (mechanism of action) work? Doxazosin is an oral drug used to treat the effects of benign prostatic hyperplasia and high blood pressure (BPH, a noncancerous enlargement of the prostate gland). It belongs to a family of drugs called adrenergic blockers called alpha-1.
If it lasts for a long time, it can not function properly in the heart and arteries. This can damage the brain, heart, and kidney blood vessels, leading to stroke, heart failure, or failure of the kidneys.
Larger randomized controlled trials have also reliably shown that doxazosin-treated patients gain weight. While doxazosin treatment patients appear to gain weight, placebo therapy patients have lost weight.
Doxazosin is widely stated to have side effects: dizziness, nausea, vertigo, hypertension, symptomatic orthostatic hypotension, malaise, and drug-related orthostatic hypotension. Such side effects include syncope, edema, and drowsiness.
Because older hypertensives have reduced diastolic left ventricular (LV) distensibility, the end-diastolic LV pressure rises easily with doxazosin volume retention, which could contribute to the development of congestive heart failure.
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