What is Doxorubicin?
Doxorubicin is a powerful chemotherapy drug used to treat a variety of cancers. It is available under the brand names Adriamycin, Caelyx and Rubex. This medication is specifically designed to target and inhibit the growth of cancer cells in various parts of the body.
Doxorubicin Uses
Doxorubicin is used to treat a wide range of cancers, including:
- Ovary, prostate, liver and thyroid cancers
- Small cell lung cancer
- Squamous cell cancer of the head and neck
-
Multiple myeloma
- Hodgkin's disease
-
Lymphomas
- Acute lymphocytic leukemia (ALL)
- Acute myeloid leukemia (AML)
- Blood, lymphatic system, bladder, breast, stomach, lungs, ovaries, thyroid, nerves, kidneys, bones and soft tissue cancers
How Does Doxorubicin Work?
- Doxorubicin is an anthracycline chemotherapy that works by slowing and stopping the growth of cancer cells.
- It affects both cancerous and normal body cells, which can lead to various side effects.
Doxorubicin Side Effects
Common Side Effects of Doxorubicin
Serious Side Effects of Doxorubicin
- Hives
- Skin rash
-
Itching
- Difficulty breathing
- Seizures
Note: Doxorubicin can cause your urine, tears, and sweat to turn reddish. This is a normal reaction and should not be mistaken for blood.
Secure your health with a second opinion. Make informed decisions and book your appointment today!
Get A Second Opinion
Precautions To Be Taken For Doxorubicin
Before starting Doxorubicin, inform your doctor if you:
- Are allergic to Doxorubicin or other medications
- Have a medical history of:
- Low blood cell counts
-
Anemia
- Neutropenia
-
Gout
- Heart problems
- Kidney or liver issues
- Radiation treatment in the chest area
How to Take Doxorubicin
- Doxorubicin is administered as an intravenous injection by a healthcare professional in a medical facility.
- The injection is typically given every 21 to 28 days.
- The duration of treatment depends on the type of cancer, your body's response and the specific medications you are receiving.
- Dosage is based on medical condition, body size and therapy response.
Ready to take control of your health journey? Book your appointment now and start your path towards wellness today!
Book an Appointment
Important Tips
- Always follow your doctor's instructions regarding dosage and duration.
- Regular monitoring by your doctor is essential to manage side effects and adjust treatment as needed.
- Avoid exposure to infections and report any signs of infection to your doctor immediately.
By understanding these aspects of Doxorubicin, patients can better navigate their treatment journey and communicate effectively with their healthcare providers.
Dosage of Doxorubicin
Adult and Pediatric Dosage Forms and Strengths:
- Injectable solution: 2 mg/ml
- Powder for injection: 10 mg, 20 mg, 50 mg
Dosing Considerations for Cancer:
Adult:
- 60-75 mg/m² intravenously (IV) every 21 days
- 60 mg/m² IV every 14 days
- 40-60 mg/m² IV every 21-28 days
- 20 mg/m²/dose once per week
Pediatric:
- 35-75 mg/m² intravenously (IV) every 21 days
- 20-30 mg/m²/dose once per week
- 60-90 mg/m² IV over 96 hours every 3-4 weeks
Missed Dose
It's important to take this drug exactly when it's meant to be taken. If you miss a dose, contact your doctor or pharmacist as soon as possible to get a new dosing schedule.
Overdose
Overdose of a drug can be accidental. If you have taken more than the prescribed Doxorubicin tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.
Warnings for some Serious Health Conditions
- The medication should be only used during pregnancy if you are in a LIFE-THREATENING condition and there is no other choice.
- Positive proof of human foetal risk is available
- Doxorubicin passes into breast milk
- Usage during breastfeeding is not recommended
- Tumor lysis syndrome and hyperuricemia are potential side effects.
- Secondary oral cancers, predominantly squamous cell carcinoma, have been linked to long-term use of the medication (i.e., greater than1 year)
- Pediatric patients, seniors, impaired liver function, concomitant radiotherapy
Storage
Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
Doxorubicin vs Daunorubicin