What is Drotaverine?

Drotaverine (also known as Drotaverine) is an antispasmodic drug similar to papaverine in structure. The medication relieves pain caused by irritable bowel syndrome, headache, and menstrual periods and is also used to relieve cervical spasms during labor.

Drotaverine, derived from benzylisoquinoline, is a synthetic pharmaceutical classified within the hydroisoquinolone drug class. Primarily composed of drotaverine, a benzylisoquinoline derivative, it acts by inhibiting phosphodiesterase-4 (PDE4).

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Drotaverine Uses

Treating twitches or spasms of smooth muscles in the stomach and heart.
Alleviating pain associated with irritable bowel syndrome (IBS).
Relieving headaches.
Easing menstrual period pain.
Reducing cervical spasms during childbirth.
Managing stomach pain.
Addressing chest pain.
Assisting in the treatment of gallstones.
Alleviating kidney pain.
Relieving renal colic pain.

Drotaverine Side Effects

Nausea
Vomiting
Dry mouth
Change in pulse rate
Dizziness
Headache
Difficulty in breathing
Skin allergic
Swelling of face, lips, eyelids and tongue
Fall in Blood pressure
Vertigo
Constipation
Sleep disorders
Dermatitis

Drotaverine Dosage

Available as oral medication.
Take it with or without food.
For adults: 40-80 mg three times a day (dosage may vary).
For children (1-6 years): 20 mg three to four times daily.
For children (over six years): Start with a 40 mg dosage.
Helps restore the balance of cyclic AMP and calcium ions in smooth muscles.
Inhibits phosphodiesterase-IV enzymes.

Missed Dose:

Skipping one or two doses of Drotaverine poses no harm.
However, timely intake is crucial for effectiveness.
Consult your doctor for advice on missed doses; take it as soon as possible if recommended.

Overdose:

Consult a doctor immediately if an overdose occurs.
Symptoms may include restlessness, confusion, and dizziness.
Severe cases may require gastric lavage.

Precautions to Follow

Inform your doctor if you are allergic to Drotaverine or any other medications.
Some inactive ingredients in the product may cause severe allergic reactions.
Discuss with your doctor if you have heart, liver, or kidney disease
Use caution in patients with genetic disorders of the skin and blood.
Avoid Drotaverine if you're experiencing allergic reactions or if you're pregnant or breastfeeding.

Warnings for Serious Health Conditions:

Liver Disease:

Use with caution in patients with liver function impairment.
Adjustments in dosage and safety monitoring are advised, especially in severe impairment.

Pregnancy:

Avoid unless benefits outweigh risks.
Consult your doctor before use.

Breastfeeding:

Not recommended due to potential adverse effects on the baby.
Consult your doctor regarding risks associated with use during breastfeeding

Storage of Drotaverine

Protect from heat, air, and light to prevent damage. Keep it in a safe place, out of children's reach. Store at room temperature between 68ºF and 77ºF (20ºC and 25ºC).

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Drotaverine vs Dicyclomine

Drotaverine	Dicyclomine
Drotaverine (INN, also known as drotaverine) is an antispasmodic drug similar to papaverine in structure. Drotaverine is a phosphodiesterase 4 inhibitor that has no anticholinergic properties.	Dicyclomine oral tablet is a prescription medicine. It's available as a brand-name Bentyl drug.
Drotaverine is an important treatment for twitches or spasms of the smooth muscles of the stomach and heart.	Dicyclomine is used to treat symptoms such as stomach spasms caused by intestinal disorders, including irritable bowel syndrome.
Some of the common and serious side effects of Drotaverine are: Nausea Vomiting Dry mouth Change in pulse rate Dizziness	Some of the common and serious side effects of Dicyclomine are: Dry mouth Dizziness Nausea Hives

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Frequently Asked Questions

1. What is drotaverine used for?

Drotaverine is used to relieve spasmodic pain associated with conditions such as biliary colic, renal colic, gastrointestinal spasms, and spasms in the urinary tract. It is also used to alleviate menstrual pain.

2. Is dicyclomine and drotaverine same?

No, dicyclomine and Drotaverine are not the same. Dicyclomine is an anticholinergic that is used to treat irritable bowel syndrome and other functional bowel disorders, while Drotaverine is an antispasmodic used to relieve smooth muscle spasms.

3. Is drotaverine safe for kidneys?

Drotaverine is generally considered safe for kidneys when used as prescribed. However, patients with pre-existing kidney conditions should consult their healthcare provider before taking it.

4. Is drotaverine safe for liver?

Drotaverine is generally safe for the liver when used as prescribed. Patients with liver conditions should consult their healthcare provider to ensure it is safe for them.

5. When should I take drotaverine?

Drotaverine should be taken as prescribed by a healthcare provider. It is typically taken when experiencing spasmodic pain, and the dosage will depend on the specific condition being treated.

6. Is drotaverine a painkiller?

Drotaverine is not a traditional painkiller. It is an antispasmodic that relieves pain by relaxing smooth muscle spasms.

7. Is drotaverine a muscle relaxant?

Yes, Drotaverine acts as a muscle relaxant specifically targeting smooth muscles in the gastrointestinal and genitourinary tracts.

8. Is drotaverine better than tramadol?

Drotaverine and tramadol serve different purposes. Drotaverine is used for relieving spasmodic pain by relaxing muscles, while tramadol is an opioid painkiller used for treating moderate to severe pain. The choice between them depends on the type of pain and the underlying condition.

9. Is drotin and drotaverine the same?

Yes, Drotin is a brand name for the drug drotaverine. They contain the same active ingredient and are used for the same indications.

10. How much time does drotaverine take to work?

Drotaverine typically starts to work within 30 minutes of oral administration, providing relief from spasmodic pain.

Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.