What is Duloxetine?

Duloxetine is categorized as a selective serotonin and norepinephrine reuptake inhibitor (SNRI), a class of drugs that elevate serotonin and norepinephrine levels in the brain, serving as antidepressants.


Uses of Duloxetine:

It is used to treat conditions such as:


What are the Side effects of Duloxetine?

The common side effects of Duloxetine are:

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Precautions

Ask our doctor about your medical history, especially if you have:

  • Mental health problems like bipolar disorder or suicidal thoughts
  • Bleeding problems
  • High blood pressure
  • Kidney disease
  • Liver disease
  • Seizures
  • Stomach ulcers
  • Avoid driving, operating machinery, or alcohol
  • Monitor your blood sugar levels
  • Discuss the side effects(if any) with the Doctor
  • This drug should only be taken during pregnancy if necessary

How to Use Duloxetine?

  • Follow prescribed dosage
  • Take with or without food as directed
  • Take it 1 or 2 times a day as prescribed
  • Take it at the same time each day
  • Consult a doctor if any side effects are noticed

Interactions

Duloxetine can slow down the removal of other medications from your body. Tell your doctor about all the medicines you take.

Duloxetine increases the risk of bleeding when combined with aspirin. Consult your doctor if you take aspirin for heart attack or stroke prevention.

Duloxetine may interact with other medications that increase the risk of bleeding or bruising, such as antiplatelet drugs, NSAIDs, and blood thinners.

Duloxetine can interact with other medicines causing bleeding or bruising, such as antiplatelet medicine (e.g., clopidogrel), NSAIDs (e.g., ibuprofen), and blood thinners (e.g., warfarin).

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Missed Dose

  • Take the dose as soon as you remember unless it is close to the next scheduled dose.
  • If nearing the next dose, skip the missed one and resume regular dosing intervals.
  • Avoid doubling up on doses.

Overdose

If excessive intake occurs with severe symptoms like unconsciousness or breathing difficulties, seek immediate medical assistance.

Overdose indications may include extreme drowsiness, loss of consciousness, seizures, or rapid heartbeat.

Storage

  • Store at room temperature, shielded from direct sunlight, heat, and moisture.
  • Keep medications out of reach of children.

Duloxetine vs Fluoxetine

Duloxetine Fluoxetine
Molecular Formula, C18H19NOS Formula: C17H18F3NO
Molar mass: 297.4146 g/mol Molar mass: 309.33 g/mol
brand name Cymbalta brand names Prozac and Sarafem
used to treat the major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain Severe depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder are all treated with it.
Drug class: Serotonin-norepinephrine reuptake inhibitor It is an antidepressant of the selective serotonin reuptake inhibitor class

Citations

Duloxetine
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Frequently Asked Questions

1. Is Duloxetine a strong painkiller?

Duloxetine is not typically considered a strong painkiller. It belongs to a class of medications called SNRIs (Serotonin-norepinephrine reuptake inhibitors), primarily used for treating depression and anxiety.

2. Is Duloxetine a potent antidepressant?

Yes, Duloxetine is considered a strong antidepressant. It belongs to a class of medications called serotonin-norepinephrine reuptake inhibitors (SNRIs).

3. What is the best time to take Duloxetine?

Duloxetine should be taken at the same time every day. Take as per the Doctor's instructions.

4. Does Duloxetine give you energy?

Yes, Duloxetine may increase energy levels in some individuals as a result of its antidepressant effects. However, the response can vary from person to person.

5. Is Duloxetine a safe and effective medication?

Yes, Duloxetine can be both safe and effective when used appropriately and under the guidance of a Doctor.

6. Can Duloxetine make you sleepy?

Duloxetine can cause drowsiness in some individuals as a side effect. If you feel excessive drowsiness or any other concerning side effects while taking Duloxetine, it's essential to discuss them with your Doctor.

7. How soon can one expect to see the effects of Duloxetine?

The drug's benefit is often seen in the first one to two weeks of treatment, while improvements in appetite, energy, and sleep may appear.

8. Can Duloxetine help nerve pain?

Duloxetine is effective in treating neuropathic pain, including pain induced by diabetic neuropathy and likely fibromyalgia.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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