What is Enalapril?

Enalapril is a prescription drug used to treat elevated blood pressure (hypertension), left ventricular dysfunction, and symptoms of congestive heart failure. It belongs to the ACE Inhibitor family of drugs and works by preventing the development of angiotensin II, which relaxes the arteries, reducing blood pressure and making it easier for the heart to pump blood. The FDA approved enalapril in December 1985.


Enalapril Uses

Enalapril is used to:

  • Control high blood pressure (alone or with other drugs)
  • Treat heart failure (in conjunction with other drugs)

By lowering certain chemicals that tighten blood vessels, enalapril allows blood to circulate more freely and the heart to pump more efficiently. This helps prevent damage to vital organs and reduces the risk of serious health issues like heart disease, heart attack, stroke, renal failure, and vision loss.

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Enalapril Side Effects

Common Side Effects:

  • Dizziness
  • Weakness
  • Skin rash
  • Cough

Serious Side Effects:

  • Breathing problems
  • Tightness in the chest
  • Liver problems (yellowing of the skin)
  • Kidney problems (inability to pass urine, blood in urine)
  • High potassium levels
  • Weight gain
  • Lightheadedness
  • Numbness
  • Shortness of breath
  • Irregular heartbeat

If you experience symptoms of infection such as persistent sore throat, cough, fever, chills, night sweats, difficulty breathing, painful or repeated urination, irregular vaginal discharge, or white patches in your mouth, contact your doctor immediately.


Precautions

Before taking enalapril, inform your doctor if you:

  • Are allergic to enalapril or other medications
  • Have a history of allergic reactions, swelling of the face, blood filtering procedures, or high potassium levels in the blood

How to Take Enalapril

Enalapril is available in immediate and extended-release (long-acting) tablets. It is taken once or twice a day, with or without food.

Dosage Forms and Strengths:

  • Brand: Vasotec
  • Form: Oral tablet (2.5 mg, 5 mg, 10 mg, and 20 mg)

Dosage for High Blood Pressure:

  • Adults (18 years and older): Starting dosage is 5 mg once per day.

Dosage for Heart Failure:

  • Adults (18 years and older): Starting dosage is 2.5 mg taken by mouth.

Missed Dose:

If you miss a dose, skip it and resume your regular schedule. Do not double the dose. Set an alarm to remind you of your doses if you miss them frequently.

Overdose:

If you overdose, seek medical attention immediately as it can lead to a medical emergency.


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Warnings for Serious Health Conditions

Swelling: Do not take enalapril if you have a history of swelling all over your body.

Low Blood Pressure: Enalapril can lower blood pressure. If you have low blood pressure, inform your doctor for dosage adjustment, especially if you have heart or kidney disease, or diabetes.

Heart Problems: Use enalapril with caution if you have ischemic heart disease as it can make you more susceptible to low blood pressure.


Pregnancy and Breastfeeding

Enalapril is generally not recommended during pregnancy but may be prescribed if the benefits outweigh the risks. Consult your doctor if you are trying to get pregnant, are pregnant, or are breastfeeding.


Storage

Store enalapril at room temperature (68ºF to 77ºF / 20ºC to 25ºC) away from heat, air, and light. Keep it out of reach of children.


Enalapril vs Telmisartan

Enalapril Telmisartan
Used to treat elevated blood pressure, left ventricular dysfunction, and congestive heart failure symptoms. Used to treat high blood pressure, heart failure, and diabetic kidney disease.
Belongs to ACE inhibitors class. Belongs to angiotensin receptor blockers (ARBs) class.
Common side effects: dizziness, weakness, skin rash Common side effects: changes in vision, dizziness, fast heartbeat, hives.

Citations

Enalapril
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Frequently Asked Questions

1. What medication can replace enalapril?

If you cannot take enalapril or other ACE inhibitors due to side effects like a dry cough, alternatives may include angiotensin receptor blockers (ARBs) such as candesartan, irbesartan, losartan, or valsartan.

2. What are the side effects of taking enalapril?

Common side effects of enalapril include dizziness, weakness, and skin rash.

3. Is enalapril bad for kidneys?

Enalapril works by widening blood vessels to reduce blood pressure and ease the heart's workload. If blood pressure is not controlled over time, it can lead to damage in blood vessels of the brain, heart, and kidneys, potentially causing stroke, heart failure, or kidney failure.

4. How quickly does enalapril work?

Enalapril works by widening blood vessels to lower blood pressure and reduce the heart's workload. It begins to work within an hour of taking it and lasts for at least 24 hours.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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