Estazolam: Uses, Dosage and Side Effects

Estazolam is a tranquilizer drug of the triazolobenzodiazepine class, marketed under the brand name Prosom, and is a benzodiazepine fused with a triazole ring. It has anxiolytic, anticonvulsant, hypnotic, relaxant effects of the sedative and skeletal muscle.


Estazolam Uses

To treat a certain sleep disorder, this drug is used (insomnia). It will help you fall asleep quicker, stay asleep longer, and reduce how much you wake up at night, so that you can get a better night's rest. Estazolam belongs to a drug class known as benzodiazepines. In order to create a soothing effect, it works on the brain. The use of this drug is typically limited to brief periods of care of 1 to 2 weeks or less. Speak to the doctor if your insomnia lasts for a longer period of time to see if you need any other medication.

How to Use Estazolam

  • Before you begin using estazolam and each time you receive a refill, read the drug guide issued by your pharmacist.
  • Take this medicine by mouth, as prescribed by your doctor, with or without food, usually just before you get to bed. The dosage will be based on your medical condition, age and treatment response.
  • Although uncommon, transient short-term memory loss can rarely be caused by this drug. Do not take a dose of this medication to minimize the risk of this unless you have time for a good night's sleep of at least 7 to 8 hours. You can have some memory loss if you have to wake up before that.
  • You may have withdrawal symptoms if you unexpectedly quit using this drug (such as nausea, vomiting, flushing, stomach cramps, nervousness, shakiness). Your doctor can lower your dose slowly in order to prevent it. 
  • When you have used estazolam for a long time or in high doses, withdrawal is more likely. If you experience withdrawal, inform your doctor or pharmacist immediately.
  • It does not work as well when this drug is used for a long time. If this drug stops functioning well, talk with your doctor.
  • While it has benefited many people, addiction can also be induced by this drug. If you have a substance use disorder (such as overuse of or addiction to drugs or alcohol), this risk could be bigger. 
  • To lower the risk of addiction, take this drug exactly as prescribed. For more info, ask your doctor.
  • If the condition continues after 7 to 10 days, or if it worsens, tell your doctor. After you quit taking this drug, you might have trouble sleeping for the first few nights. This is called rebound sleeplessness and is natural. .Typically, it will go away after 1 or 2 nights

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Side Effects of Estazolam

Important Precautions When Taking Estazolam

  • Tell your doctor or pharmacist whether you are allergic to estazolam or to other benzodiazepines (such as diazepam, lorazepam) or if you have any other reactions before taking estazolam. There may be inactive ingredients in this substance that may cause allergic reactions or other problems. For more guidance, talk to your pharmacist.
  • Tell your doctor or pharmacist your medical history before taking this medicine, particularly: kidney disease, liver disease, lung/breathing problems (such as chronic obstructive pulmonary disease-COPD, sleep apnea), mental/mood problems (such as depression, suicidal thoughts), personal or family history of substance use disorders (such as drug overdose or addiction).
  • Because this drug makes you drowsy, before you can do it safely, do not drive, use machinery, or do something that involves alertness. You might become more drowsy and dizzy with alcohol or marijuana (cannabis). Stop alcoholic drinks. If you use marijuana, talk to your doctor (cannabis).
  • Inform your doctor or dentist of all the medications you need before having surgery (including prescription drugs, nonprescription drugs, and herbal products).
  • Older adults may be more susceptible, particularly dizziness, confusion, unsteadiness, and extreme drowsiness, to the side effects of this medication. The risk of falling may be raised by these side effects.
  • During pregnancy, Estazolam must not be used. An unborn baby could be affected. Use a reliable method of birth control when taking this medication if you are a woman of childbearing age. Do not take this drug if you are considering a pregnancy. Tell your doctor right away if you are planning to get pregnant or think that you might be pregnant.
  • This drug can pass into breast milk and have adverse effects on a child who is nursing. Before breast-feeding, consult the doctor.

Dosage Instructions for Estazolam Use

Normal Adult Insomnia Dose:

Orally 1 to 2 mg at bedtime

Use:Short-term insomnia management

Normal Geriatric Dosage for Sleeplessness:

1 mg at bedtime orally

Observations:

  • Increases in doses should be initiated with caution
  • A starting dose of 0.5 mg should be considered for small or weakened elderly patients

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Estazolam Vs Alprazolam

Estazolam Alprazolam
Brand name Prosom Brand name Xanax
Class triazolobenzodiazepine Class triazolobenzodiazepine
Dosage Forms: oral tablet (1 mg; 2 mg) Dosage available 0.25 mg or 1 mg
To treat a certain sleep disorder, this drug is used (insomnia). It is used for short-term management of anxiety disorders, specifically panic disorder and generalized anxiety disorder
It works by slowing the activity in the brain to allow sleep. It works by decreasing the unusual excitement of the brain.
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Frequently Asked Questions

1. What is estazolam used for?

The benzodiazepine is estazolam. Estazolam affects brain chemicals that may be unbalanced and cause issues with sleep (insomnia). Estazolam is used for the treatment of symptoms of insomnia, such as difficulties falling or staying asleep.

2. How long will Estazolam remain in your system?

The range of estimates for the mean half-life of estazolam for removal ranged from 10 to 24 hours. Mass balance tests by Radiolabel show that the main route of excretion is through the kidneys. 87 percent of the radioactivity administered was excreted in human urine after 5 days.

3. Can Estazolam get you high?

Estazolam has the potential for abuse, as shown in primate studies. Abuse can occur recreationally, where the drug is used to achieve a high, or medically, when it is used against medical advice for extended periods.

4. Is Estazolam a controlled substance?

Estazolam is a controlled drug under DEA Schedule IV. Substances in Schedule IV of the DEA have a low risk for abuse compared to Schedule III substances. Estazolam is an insomnia-treated orally available benzodiazepine.

5. What is Estazolam's half-life?

The range of estimates for the mean half-life of estazolam for removal ranges from 10 to 24 hours.

6. How quickly does Estazolam work?

Once you begin taking estazolam, your sleep issues should improve within 7 to 10 days. If your sleep issues do not improve during this period, if they worsen during your care at any time, or if you experience any odd changes in your thinking or actions, call your doctor. Estazolam may be developing patterns.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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