What is Etoricoxib?

Etoricoxib is a non-steroidal anti-inflammatory drug (NSAIDs), that acts by reducing the cyclo-oxygenase-2 (COX-2) enzyme, which is a natural chemical. This enzyme helps the body to produce prostaglandins.

It is available in tablet form and injection.


Uses of Etoricoxib

Used for the treatment of conditions such as:

  • Gout
  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
  • Chronic low back pain
  • Acute and chronic musculoskeletal pain

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Side Effects of Etoricoxib

Some of the common and major side effects of Etoricoxib are:


Precautions To Follow

  • Inform your doctor about any allergies to etoricoxib or other medications.
  • Discuss any medical history, including asthma, stomach pain, or heart conditions, with your doctor before use.

How to Use

  • Take etoricoxib tablets once daily, with or without food.
  • Dosage may change based on the condition being treated:
    • Osteoarthritis: 30 mg daily, may increase to 60 mg if needed.
    • Rheumatoid arthritis and ankylosing spondylitis: 60 mg daily, may increase to 90 mg if necessary.
    • Acute gout: 120 mg daily for up to eight days.
    • Pain after dental surgery: 90 mg daily for three days.

Missed Dose

Take missed doses as soon as remembered, but do not double up on doses.


Overdose

Take a quick call to a doctor if you suspect an overdose.


Interactions:

Etoricoxib may interact with:

  • Anticoagulants: Warfarin, aspirin
  • Antibiotics: Rifampicin
  • Immunosuppressants: Methotrexate
  • Antihypertensives: Enalapril, ramipril, losartan, valsartan, minoxidil
  • Diuretics
  • Antiarrhythmics: Digoxin
  • Antiasthmatics: Salbutamol
  • Oral contraceptives

No interactions with food have been found.


Warnings for Serious Health Conditions

Pregnant women should use etoricoxib only if necessary after consulting a doctor.

Breastfeeding women must inform the doctor before using etoricoxib due to potential risks to the infant.


Who should not take Etoricoxib?

Etoricoxib should not be taken by individuals with:

  • Stomach ulcers or bleeding
  • Severe kidney or liver disease
  • Colitis
  • Uncontrolled blood pressure
  • Heart failure
  • Stroke
  • Other heart problems

Storage Instructions

  • Store at temperature between 68ºF and 77ºF (20ºC and 25ºC)
  • Keep away from heat, light, and moisture.
  • Keep out of reach of children.

Etoricoxib vs Naproxen

Etoricoxib Naproxen
Etoricoxib is a non-steroidal anti-inflammatory drug (NSAIDs) which is used as anti-inflammatory painkillers. Naproxen is a pain reliever that relieves inflammation and stiffness in the joints. The medication works by blocking the enzyme that makes prostaglandins.
Etoricoxib is used to minimise inflammation (swelling) and alleviate pain in arthritic disorders including osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Naproxen tablets are used for treating pain and inflammation of various severe conditions. It includes:
  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
Some of the common and major side effects of Etoricoxib are:
  • Flu
  • Indigestion
  • Stomach pain
  • Diarrhea
  • Peripheral edema
The most common side effects of Naproxen are:
  • Stomach pain
  • Constipation
  • Diarrhea
  • Gas

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Frequently Asked Questions

Etoricoxib is used to treat conditions involving pain and inflammation, such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gout, and post-operative dental pain.

Yes, Etoricoxib is considered a potent pain reliever, particularly for inflammatory conditions like arthritis.

Yes, Etoricoxib may cause side effects and may vary from person to person. It is good to consult the doctor if you feel uneasy after taking medication.

Etoricoxib, as a COX-2 inhibitor, is generally considered safer for kidney function compared to COX-1 inhibitors like naproxen and ibuprofen. However, individual factors and medical history should be considered

Yes, some studies found that etoricoxib (90 mg once daily) was more effective than naproxen in treating rheumatoid arthritis. However, take medicine as per the doctor's advice before using it.

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