Etoricoxib: Uses, Side Effects, and Dosage

Etoricoxib is a non-steroidal anti-inflammatory drug (NSAIDs), that acts by reducing the cyclo-oxygenase-2 (COX-2) enzyme, which is a natural chemical. This enzyme helps the body to produce prostaglandins.

It is available in tablet form and injection.

Uses of Etoricoxib

Used for the treatment of conditions such as:

  • Gout
  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
  • Chronic low back pain
  • Acute and chronic musculoskeletal pain

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Side Effects of Etoricoxib

Some of the common and major side effects of Etoricoxib are:

Precautions to Follow

  • Inform your doctor about any allergies to etoricoxib or other medications.
  • Discuss any medical history, including asthma, stomach pain, or heart conditions, with your doctor before use.
  • If you have untreated or unmanaged high blood pressure, please inform your doctor, as Etoricoxib can potentially raise blood pressure in some individuals.
  • If you are undergoing treatment for an illness, it's best to avoid using Etoricoxib as it might worsen the fever.
  • If you smoke, have diabetes, or suffer from high cholesterol, you should not use Etoricoxib, as it may increase your risk of heart attack or stroke.
  • After taking Etoricoxib, make sure not to lie down for at least 30 minutes.
  • Etoricoxib should not be taken by anyone who has had a heart attack or a stroke.
  • This medication is never given to pregnant women unless necessary. Before using it, talk to your doctor about the risks and benefits. Based on your current health, your doctor may suggest a safer alternative.

How to Use Etoricoxib?

  • Take etoricoxib tablets once daily, with or without food.
  • Dosage may change based on the condition being treated:
    • Osteoarthritis: 30 mg daily, may increase to 60 mg if needed.
    • Rheumatoid arthritis and ankylosing spondylitis: 60 mg daily, may increase to 90 mg if necessary.
    • Acute gout: 120 mg daily for up to eight days.
    • Pain after dental surgery: 90 mg daily for three days.

How Etoricoxib works?

Etoricoxib works by blocking the enzyme COX-2, which produces prostaglandins that cause pain and inflammation. By inhibiting COX-2, it helps reduce pain, swelling, and inflammation, particularly in conditions like arthritis and gout, without affecting COX-1, which protects the stomach.

Dosage of Etoricoxib

Missed Dose

Take missed doses as soon as remembered, but do not double up on doses.

Overdose

Take a quick call to a doctor if you suspect an overdose.


Interactions

Etoricoxib may interact with:

  • Anticoagulants: Warfarin, aspirin
  • Antibiotics: Rifampicin
  • Immunosuppressants: Methotrexate
  • Antihypertensives: Enalapril, ramipril, losartan, valsartan, minoxidil
  • Diuretics
  • Antiarrhythmics: Digoxin
  • Antiasthmatics: Salbutamol
  • Oral contraceptives

No interactions with food have been found.


Warnings for Serious Health Conditions

  • Pregnant women should use etoricoxib only if necessary after consulting a doctor.
  • Breastfeeding women must inform the doctor before using etoricoxib due to potential risks to the infant.

Who should not take Etoricoxib?

Etoricoxib should not be taken by individuals with:

  • Stomach ulcers or bleeding
  • Severe kidney or liver disease
  • Colitis
  • Uncontrolled blood pressure
  • Heart failure
  • Stroke
  • Other heart problems

Storage Instructions for Etoricoxib

  • Store at temperature between 68ºF and 77ºF (20ºC and 25ºC)
  • Keep away from heat, light, and moisture.
  • Keep out of reach of children.

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How quickly does Etoricoxib show results?

Etoricoxib typically starts showing results within a few hours, with pain and inflammation relief often felt within 1 to 2 hours. However, full effects may take a few days for chronic conditions like arthritis. The response time can vary based on the individual and the condition being treated. If you don’t notice improvement or experience side effects, consult your doctor.


Etoricoxib vs Naproxen

Etoricoxib

Naproxen

Etoricoxib is a non-steroidal anti-inflammatory drug (NSAIDs) which is used as anti-inflammatory painkillers.

Naproxen is a pain reliever that relieves inflammation and stiffness in the joints. The medication works by blocking the enzyme that makes prostaglandins.

Etoricoxib is used to minimise inflammation (swelling) and alleviate pain in arthritic disorders including osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Naproxen tablets are used for treating pain and inflammation of various severe conditions. It includes:

  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis

Some of the common and major side effects of Etoricoxib are:

  • Flu
  • Indigestion
  • Stomach pain
  • Diarrhea
  • Peripheral edema

The most common side effects of Naproxen are:

  • Stomach pain
  • Constipation
  • Diarrhea
  • Gas

Citations

Etoricoxib
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Frequently Asked Questions

What types of treatments is etoricoxib used for?

Etoricoxib is used to treat conditions involving pain and inflammation, such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gout, and post-operative dental pain.

Is etoricoxib a strong painkiller?

Yes, Etoricoxib is considered a potent pain reliever, particularly for inflammatory conditions like arthritis.

Is etoricoxib safe for kidneys?

Etoricoxib, as a COX-2 inhibitor, is generally considered safer for kidney function compared to COX-1 inhibitors like naproxen and ibuprofen. However, individual factors and medical history should be considered.

What are etoricoxib and thiocolchicoside tablets used for?

Etoricoxib and thiocolchicoside tablets are used to treat pain and muscle spasms. Etoricoxib reduces inflammation, while thiocolchicoside acts as a muscle relaxant.

Can I take etoricoxib and thiocolchicoside tablets together?

Yes, etoricoxib and thiocolchicoside tablets are often combined to treat pain and muscle spasms effectively, providing both anti-inflammatory and muscle relaxant effects.

What should I avoid while taking the etoricoxib drug?

While taking the etoricoxib drug, avoid consuming alcohol and smoking, as these can increase the risk of gastrointestinal problems and cardiovascular issues.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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