What is Febuxostat?

Febuxostat belongs to the xanthine oxidase inhibitors class of drugs. It works by lowering the level of uric acid produced in the body.

Febuxostat, also known by its brand names Uloric and Adenuric, is used for the long-term treatment of gout caused by elevated uric acid levels. It is usually prescribed for those who are unable to take allopurinol.

Uses of Febuxostat

Febuxostat oral tablet is used to treat hyperuricemia (constantly high levels of uric acid) in adults.

Febuxostat helps decrease the symptoms of gout

  • Helps decrease the symptoms of gout
  • Pain
  • Swelling
  • Redness
  • Heat
  • Soreness
  • Stiffness in certain joints

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How to use Febuxostat 80 Mg Tablet?

  • Read the Medication guide provided by your doctor before starting Febuxostat and with each refill.
  • Take Febuxostat orally once daily, with or without food, as directed by your doctor.
  • Dosage is based on your health condition and response to treatment.
  • Take Febuxostat daily for maximum benefit.
  • Expect possible gout attacks in the initial months of treatment as your body eliminates excess uric acid.
  • Febuxostat is not a pain reliever; your doctor may prescribe additional medication such as colchicine or NSAIDs for pain management.
  • Consult your doctor with any concerns.

Side Effects of Febuxostat

What Are the Precautions of Febuxostat?

  • Inform your doctor any allergies to febuxostat or other substances.
  • Discuss your medical history, including cancer, heart failure, stroke, liver or kidney disease, or organ transplant, with your doctor.
  • Use febuxostat during pregnancy or breast feeding only if absolutely necessary, after consulting with your doctor about potential risks.

Dosage

Missed Dose:

If you forget a dose, take it when you remember. If it's near the time for your next dose, skip the missed one. Do not double the dose.

Overdose:

Seek emergency medical help if you or someone else experiences serious symptoms such as passing out or trouble breathing due to an overdose. Symptoms may include severe drowsiness, fainting, seizures, or a fast heartbeat.

Interactions:

Drug interactions may alter how your medications work or increase the risk of serious side effects.

Keep a list of all medications you use and share it with your doctor and pharmacist to prevent drug interactions. Do not alter dosages without your doctor's permission.

Storage Instructions:

Store at room temperature away from sunlight, heat, and moisture. Keep out of reach of children. Do not flush medications down the toilet. Discard expired or unused medication properly.

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Febuxostat vs Allopurinol

Febuxostat Allopurinol
Formula: C16H16N2O3S Formula: C5H4N4O
Molar mass: 316.374 g/mol Molar mass: 136.112 g/mol
Brand names Uloric and Adenuric Brand name Zyloprim
Febuxostat is a medication used for long-term treatment of gout due to high uric acid levels. Allopurinol is a medication used for decreasing high blood uric acid levels.
It is generally recommended for people who cannot take allopurinol. It is specifically used to avoid gout, certain forms of kidney stones, and elevated uric acid levels.
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Frequently Asked Questions

1. What is febuxostat used for?

Febuxostat is a medication that is used to avoid gout attacks but not to treat them until they have occurred.

2. What is the side effect of febuxostat?

In the early stages of treatment, the most common side effect of febuxostat is a rise in gout attacks. However, if you do experience a gout spell, do not stop taking febuxostat. Treat the assault as you usually would. The majority of people have no such side effects.

3. What is Feburic 40?

Feburic 40 is a brand name for febuxostat 40 mg, a medication used to lower uric acid levels in patients with gout.

4. What are the uses of Febustat 40 mg?

Febustat 40 mg is used primarily to manage and prevent gout by reducing uric acid levels in the blood.

5. Is febuxostat toxic to the liver?

Hepatotoxicity is a condition in which the liver is damaged. Liver test anomalies have been identified in 2% to 13% (average 3.5%) of febuxostat patients, but the symptoms are usually mild to moderate and self-limited.

6. Is febuxostat good for kidneys?

Febuxostat has been shown to be safe and effective in patients with mild to extreme renal impairment, and there is no need to change the dose in these cases. To assess the effectiveness and safety of febuxostat in patients with CKD and hyperuricemia, we conducted a systematic review and meta-analysis.

7. Does febuxostat increase blood pressure?

In patients with mild-to-moderate renal disability, the safety and efficacy of febuxostat have been demonstrated without dose adjustments. Allopurinol and febuxostat have been shown in a number of studies to be successful in lowering blood pressure (BP) and slowing the progression of CKD.

8. Which is better: allopurinol or febuxostat?

Febuxostat was more effective than allopurinol at the widely used fixed daily dose of 300 mg in lowering serum urate at a daily dose of 80 mg or 120 mg. Both treatment groups saw similar decreases in gout flares and tophus fields.

9. Can febuxostat cause diarrhea?

The more common side effects include gout flares, liver function abnormalities, diarrhea, nausea, rash, headache, and edema. So, yes it can cause diarrhea in some patients.

10. What precautions should I take while using febuxostat?

Regular monitoring of liver function, uric acid levels, and cardiovascular health is important while using febuxostat.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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