What is Folitrax?

• Folitrax is a brand name for a medication called methotrexate.
• Methotrexate is a type of medication known as a disease-modifying antirheumatic drug (DMARD).

• Choriocarcinomas: Used to treat cancers occurring in the uterus of women.
• Rheumatoid Arthritis: Used alone or with other medications to treat severe rheumatoid arthritis. It helps alleviate joint pain and swelling, typically accompanied by rest and physical therapy.
• Psoriasis: Employed in the treatment of severe psoriasis, characterized by red, swollen skin often covered by scales.

• Diarrhea
• Joint pain
• Stomach pain
• Swelling of feet or lower legs
• Dizziness
• Fever or chills
• Unusual bleeding
• Blurred vision
• Hair loss
• Loss of appetite
• Nausea or Vomiting
• Pale skin
• Skin rash

• Do not use the medicine for an extended period to avoid liver damage and cirrhosis.
• Higher doses of the medicine may affect your kidneys.
• Individuals with rheumatoid arthritis or psoriasis should avoid the medicine if they have liver issues or consume alcohol.
• Those with immunodeficiency or blood disorders like anaemia, leukopenia, or thrombocytopenia may not be suitable for this medicine.
• Folitrax 7.5 Tablet is highly unsafe during pregnancy and breastfeeding, causing potential harm to the developing child.
• Stay hydrated by drinking plenty of fluids while taking this medicine.
• Always take folic acid as recommended by your doctor to reduce side effects.
• Folitrax 7.5 Tablet may take 6 to 8 weeks to show results, so continue taking it as prescribed.
• Avoid alcohol consumption while taking this medicine to minimize the risk of side effects.

Lung Toxicity:

• This medicine may cause serious lung injuries like pulmonary fibrosis and interstitial pulmonary infiltrates.
• Symptoms of difficulty breathing and signs of pulmonary impairment should be promptly reported to the doctor.
• Treatment should be stopped if these symptoms occur.

Skin Reactions:

• Serious skin reactions such as Stevens-Johnson syndrome, skin necrosis, and skin ulceration may occur.
• Inform the doctor immediately if any symptoms arise.
• Appropriate corrective measures may be necessary based on the patient's clinical condition.

Infection Susceptibility:

• The use of this medicine may weaken the immune system, increasing vulnerability to infections.
• Avoid contact with infected individuals.
• Report any signs or symptoms of infection to the doctor promptly.
• Adjustments to the dose or replacement with an alternative medicine may be required.

Driving or Operating Equipment:

• The medicine may cause dizziness, tiredness, somnolence, and blurred vision in some patients.
• Avoid activities requiring high mental alertness, such as driving or operating heavy machinery.

Dosage:

• Take the medicine once a week on the same day.
• Take it exactly as advised by your doctor. It may take several weeks or months to see the benefits.
• Do not stop taking it unless instructed by your doctor.

Over Dose:

• Never take more than what is prescribed to you. Symptoms of Folitrax 15mg Overdose Tablet include gastrointestinal bleeding, vomiting, and diarrhea.
• Patients with liver conditions may develop liver toxicity and side effects such as shortness of breath, dry cough, and fever.
• Even a single overdose may be fatal; therefore, the patient, doctor, and pharmacist should be very careful when administering this medicine.

Missed Dose:

• If you missed a dose or forgot to take it, you should take it when you remember.
• Do not take a double dose, however, if it is near the time of your next dose.
• You should be careful and avoid missed doses.

Interactions

• This medicine interacts with cyclosporine, which is often administered after an organ transplant. This medicine also interacts with drugs such as ibuprofen.
• Combining 7.5mg Folitrax Injection with certain non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, aceclofenac, acemetacin, and diclofenac can lead to severe and potentially fatal bone marrow suppression, aplastic anemia (a condition where the body stops producing new blood cells), and gastrointestinal toxicity.