What is Humira?

Humira (adalimumab) is a tumour necrosis factor (TNF) inhibitor that decreases the inflammatory effects of a substance in the body. It is used in adults and children to treat these conditions:

Additionally, Humira is used to treat several inflammatory disorders in adults, including:

  • Rheumatoid arthritis
  • Psoriatic arthritis
  • Ankylosing spondylitis
  • Plaque psoriasis
  • Hidradenitis suppurativa

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Humira Uses

Humira is a medicine that is used to relieve the pain and swelling associated with many forms of arthritis, which include:

  • Rheumatoid
  • Psoriatic
  • Juvenile idiopathic
  • Ankylosing spondylitis

This medicine is used for the treatment of various skin conditions like plaque-type psoriasis and hidradenitis suppurativa.

It functions by stopping the body's immune system from developing a protein called tumour necrosis factor (TNF), which causes joint swelling and damage in arthritis and red scaly patches in psoriasis.

TNF blockers, such as Humira, are medicines that reduce joint swelling to help prevent further joint injury and maintain joint function.


Humira Side effects

Most common side effects of Humira are:

  • Swelling in the injection site
  • Upper respiratory infections
  • Headache
  • Rash

Serious side effects of Humira are:

  • Heart failure
  • Feeling short of breath
  • Sudden weight gain
  • Swelling of the ankles
  • Lupus-like syndrome
  • Chest discomfort
  • Feeling short of breath
  • Joint pain
  • Nerve disorders
  • Dizziness
  • Weakness in the arms
  • Blurred problems
  • Blood disorders
  • Liver damage
  • Loss of appetite
  • Jaundice

Keep in mind that your doctor approved this drug because he or she feels the value to you outweighs the risk of side effects.

The majority of people who take this drug do not experience any significant side effects. If you experience those symptoms of infection when taking this medicine, contact your doctor right away.


Precautions

  • Before using Humira, talk to your doctor if you are allergic to it or any other medications.
  • The product can contain inactive ingredients that can cause serious allergic reactions or other problems.
  • Before using Humira, talk with your doctor if you have any medical history such as Hepatitis B, TB infection, Bone marrow problems, Seizures, certain brain and nerve disorders, cancer, heart disease and lupus.

How to take Humira?

  • This drug should be taken exactly as directed. As instructed by your doctor, inject this drug under the skin on the thigh or abdomen every other week or once a week in some cases.
  • If you're taking this drug to treat psoriasis, hidradenitis suppurative, Crohn's disease, ulcerative colitis, or uveitis, your doctor can give you a different schedule or a higher dose at first treatment.
  • Clean the injection site with rubbing alcohol before injecting each dose. To minimise damage under the skin, change the injection site every time.
  • A new injection site should be at least 1 inch (2.5 centimetres) away from the old one. Do not inject into any swollen, bruised, red, or rough areas of the skin.

Dosage of Humira

Humira comes in three forms:

A single-dose pen.

Strengths:

  • 40 mg/0.4 mL
  • 40 mg/0.8 mL
  • 80 mg/0.8 mL

A single-dose prefilled syringe.

Strengths:

  • 10 mg/0.1 mL
  • 10 mg/0.2 mL
  • 20 mg/0.2 mL
  • 20 mg/0.4 mL
  • 40 mg/0.4 mL
  • 40 mg/0.8 mL
  • 80 mg/0.8 mL

A single-dose vial of liquid solution.

Strengths:

  • 40 mg/0.8 mL

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Missed Dose

  • If you forget to take a Humira dose, take it as soon as you remember. The next dose can be taken at the usual time to get back on track.
  • Set a reminder on your phone to ensure you don't forget to take your medication. You may also use a calendar to keep track of your schedule.

Overdose

Overdose of a drug can be accidental. If you have taken more than the prescribed Humira tablets, there is a chance of getting a harmful effect on your body's functions.

Overdose of a medicine can lead to some medical emergency.


Warning for certain Health Conditions

Pregnancy:

  • Pregnancy categories are no longer used by the Food and Drug Administration (FDA) to define the level of risk associated with taking prescription drugs during pregnancy.
  • Humira can only be used during breastfeeding if necessary, according to the manufacturer. Humira is not considered to be safe to take during pregnancy.
  • If you are pregnant or planning to be pregnant, then talk with your doctor before taking Humira.

Breastfeeding:

  • According to the drug maker, you cannot breastfeed when taking Humira. Humira may be passed on to a breastfed infant by human breast milk.
  • However, there isn't enough information to decide if the sum is safe or could hurt the child.
  • Consult your doctor if you intend to breastfeed or are actually doing so. They will advise you on how to feed your child properly and what care options are available.

Storage

  • Direct contact with heat, air and light may damage your medicines. The exposure of medicine may cause some harmful effects.
  • The medicine must be kept in a safe place and out of children's reach. It should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).

Humira vs Stelara

Humira Stelara
Humira (adalimumab) is a tumour necrosis factor (TNF) inhibitor that decreases the the inflammatory effects of a substance in the body. Stelara (ustekinumab) is an immunosuppressant that acts by lowering the effects of a chemical compound in the body that triggers inflammation.
Humira is used to relieve the pain and swelling associated with many forms of arthritis. Stelara is a drug that is used to treat plaque psoriasis in adults and children aged 6 and up. It's also used to treat adults with psoriatic arthritis, and it's often combined with another drug named methotrexate.
Most common side effects of Humira are:
  • Swelling in the injection site
  • Upper respiratory infections
  • Headache
  • Rash
Some of the common side effects of Stelara are:
  • Headache
  • Respiratory infections
  • Fatigue
  • Redness at the injection site
  • Vaginal yeast infections
Cefaclor is a cephalosporin-type antibiotic used to treat many kinds of bacterial infections such as middle ear, skin, urine, and respiratory tract infections. This medication is used for treating a number of bacterial infections such as strep throat, pneumonia, otitis media, urinary tract infections, gonorrhea, and Lyme disease.
Molar mass: 367.808 g/mol Molar mass: 453.452 g/mol

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Frequently Asked Questions

1. What exactly does Humira do?

Humira is a medicine that is used to relieve the pain and swelling associated with many forms of arthritis which include rheumatoid, psoriatic, juvenile idiopathic, ankylosing spondylitis. This medicine is used for the treatment of various skin conditions like plaque-type psoriasis, hidradenitis suppurativa.

2. What are the worst side effects of Humira?

Serious side effects of Humira are:

  • Heart failure
  • Feeling short of breath
  • Sudden weight gain
  • Swelling of the ankles

3. What kind of drug is Humira?

Humira is a TNF blocker (tumour necrosis factor inhibitor). By inhibiting TNF function, the drug suppresses the immune system. TNF is a protein formed by the immune system of the body. TNF is developed in excess by certain people with autoimmune diseases.

4. Is Humira worth the risk?

Humira belongs to the TNF blocker class of biologics. The immune system is suppressed by these drugs. Although these medications may be effective in treating the symptoms of a number of inflammatory diseases, they also raise the risk of severe and even fatal infections and cancers in their users.

5. How long can you stay on Humira?

Humira (adalimumab) is a long-term therapy for rheumatoid arthritis. Your doctor will monitor your prescription at regular intervals to ensure that you continue to benefit from Humira. Humira dosage varies and is dictated by the condition being treated. Many people, on the other hand, continue to take Humira for years.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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