What is Indomethacin?

Indomethacin's oral capsule is a prescription medication. It is only available as a generic drug. It's also available as a rectal suppository and an oral liquid.

Indomethacin is an anti-inflammatory, non-steroidal drug (NSAID). Indomethacin is used to treat these conditions:


Indomethacin Uses

  • Indomethacin is used to alleviate inflammation, gout, bursitis, tendonitis-induced discomfort, swelling, and joint stiffness.
  • It is also used to alleviate pain from other conditions that are different. It works by blocking the development of certain natural substances that cause inflammation in the body.
  • If you are treating a chronic disease such as arthritis, ask your doctor for non-drug therapies and other drugs to treat the pain. These treatments help alleviate swelling and pain.

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Indomethacin Side Effects

Some of the common side effects of Indomethacin are:

Some of the serious side effects of Indomethacin are:

  • Shortness of breath
  • Swelling of the abdomen
  • Fever
  • Blisters
  • Rash
  • Hives
  • Hoarseness
  • Pale skin
  • Fast heartbeat
  • Nausea
  • Back pain
  • Painful urination
  • Blurred vision

If you have any of these serious symptoms, immediately contact your doctor for further assistance. In any case, if you get any kind of reaction in your body due to Indomethacin, try avoiding it.

A doctor advised you to take the medicines after seeing your problems and the benefits of this medicine, which are greater than the side effects.

The majority of the people who use this medicine don’t show any side effects. Get medical help immediately if you get any severe Indomethacin side effects.


Precautions

Before taking Indomethacin, talk with your doctor if you are allergic to it or any other medications.

The product may contain some inactive ingredients, which can cause serious allergic reactions and other serious problems.

Before using the Indomethacin talk with your doctor if you have any medical history especially:

  • Asthma
  • Bleeding or clotting problems
  • Heart disease
  • High blood pressure
  • Liver disease
  • Esophagus problems
  • Stroke

How to Take Indomethacin?

  • Indomethacin comes as a tablet, a sustained-release (long-acting) capsule, and a suspension to be taken orally and used rectally as a suppository.
  • The capsules of indomethacin and liquid are typically taken two to four times a day.
  • Indomethacin suppositories are usually given two to four times a day, and extended-release capsules are normally administered once or twice a day.
  • Swallow the extended-release capsules whole; do not cut, chew, or crush them. Shake the suspension well before each application to mix the drug equally.

Dosage Forms and Strengths

Generic

  • Form: oral immediate-release capsule
  • Strengths: 25 mg and 50 mg
  • Form: oral extended-release capsule
  • Strengths: 75 mg

Dosage for moderate to severe Rheumatoid Arthritis

Adult Dosage: The medication should be taken 2 to 3 times a day of 25 mg.

Dosage for moderate to severe Ankylosing Spondylitis

Adult dosage: The medication should be taken 2 to 3 times a day.

Missed Dose

Missing one or two doses of Indomethacin won’t have any effect on your body. The skipped dose causes no problem. But with some medication, it won’t work if you don’t take the dosage on time.

If you miss a dose some sudden chemical change may affect your body. In some cases, your doctor would advise you to take the prescribed medicine as soon as possible if you have missed the dose.

Overdose

Overdose of a drug can be accidental. If you have taken more than the prescribed Indomethacin tablets there is a chance of getting a harmful effect on your body’s functions.

Overdose of a medicine can lead to some medical emergency.


Warnings for some Serious Health Conditions

For people with Heart Conditions:

Indomethacin can increase your risk of developing a stroke or heart attack. Higher blood pressure levels can also be caused by it.

For people with Stomach Problems:

Indomethacin can increase your risk of stomach and bowel swelling or bleeding. It can increase the risk of ulcers as well.

For people with Kidney Problems:

When you take Indomethacin, your kidneys cannot function as well. They may be damaged, or blood flow to your kidneys may be reduced.


Storage

  • Direct contact with heat, air, and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach.
  • Mainly, the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Before taking Indomethacin, consult your Doctor. If you face any problems or get any side effects after taking Indomethacin, rush immediately to your nearest hospital or consult your doctor for better treatment.
  • Carry your medications in your bag while travelling to avoid any immediate emergencies. Follow your prescription and your Doctor's advice whenever you take Indomethacin.

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Indomethacin vs Ibuprofen

Indomethacin Ibuprofen
The oral capsule of Indomethacin is a prescription medication and is only available as a generic drug. It's also available as a rectal suppository and an oral liquid. Ibuprofen is used for relieving the symptoms of arthritis, fever and menstrual types of pain. This is a non-steroidal anti-inflammatory drug.
Indomethacin is used to alleviate inflammation, gout, bursitis, and tendonitis-induced discomfort, swelling, and joint stiffness. The medication is used for relieving the pain from various conditions like headache, dental pain, menstrual cramps and arthritis.
Some of the common side effects of Indomethacin are:
  • Headache
  • Dizziness
  • Vomiting
  • Diarrhea
  • Constipation
Some of the common side effects of Ibuprofen are:
  • Diarrhea
  • Nausea
  • Vomiting
  • Dizziness
  • Bloating
  • Edema

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Frequently Asked Questions

1. What is Indomethacin used for?

Indomethacin is used to relieve mild to the extreme pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by joint lining breakdown), rheumatoid arthritis (arthritis caused by joint lining swelling) and ankylosing spondylitis.

2. Is Indomethacin stronger than ibuprofen?

Indomethacin is an anti-inflammatory drug and is much better than ibuprofen. So, 50 mg Indomethacin is much stronger than 600 mg of ibuprofen.

3. Does Indomethacin make you sleepy?

Some may feel dizzy, lightheaded, drowsy, or less alert than they typically are because of this medication. Even if taken at bedtime, some people can feel drowsy or less alert when they awaken.

4. How is Indomethacin used?

Indomethacin is an anti-inflammatory non-steroidal drug (NSAID) that decreases fever, pain and inflammation. Ibuprofen (Motrin) and naproxen are similar (Naprosyn, Aleve). Indomethacin acts by reducing prostaglandin production.

5. How does Indomethacin make you feel?

There might be an upset stomach, heartburn, headache, drowsiness or dizziness. Tell your physician or pharmacist immediately if any of these symptoms persist or worsen.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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