What is Ketorolac?

Ketorolac belongs to the class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) used for treating inflammation and pain. The medication is more effective than other NSAIDs, helping to reduce pain from

  • Inflammatory
  • Non-inflammatory causes

Ketorolac was approved by the FDA in November 1989. It works by blocking the enzyme that cells use to make prostaglandins. Ketorolac helps reduce the production of prostaglandins and chemicals that cause;

Uses of Ketorolac

Keterolac is primarily used in

  • Treatment of moderate to severe pain in adults
  • Before and after medical procedures or surgery
  • Recovery by reducing pain
  • Decreases swelling, pain, and fever

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Side Effects of Ketorolac

Some of the common side effects of Ketorolac are:

  • Headache
  • Dizziness
  • Drowsiness
  • Diarrhea
  • Constipation
  • Gastric
  • Sores in the mouth
  • Sweating

Some of the serious side effects of Ketorolac are:

Contact your doctor for serious symptoms. If you experience any adverse reactions, avoid Ketorolac. Seek immediate medical help for serious side effects.


Precautions To Follow

Before taking the medication, talk to the doctor if you are allergic and have any medical history, such as:

  • Asthma
  • Bleeding or clotting problems
  • Blood disorders
  • Heart disease
  • High blood pressure
  • Liver disease
  • Nasal polyps
  • Stomach or intestinal problems
  • Stroke
  • Swelling of ankles

Sometimes serious kidney problems can occur due to the use of NSAID medication, including Ketorolac. The problem can be serious if a person is facing dehydration. Drink enough water to prevent dehydration.


How to Use Ketorolac?

  • Read the prescription label provided by the doctor
  • Take with a full glass of water every 4-6 hours
  • Avoid lying down immediately after taking
  • If stomach upset occurs, take it with food, milk, or antacid
  • Dosage based on medical condition and response to treatment
  • Take the lowest effective dose for the shortest time to reduce side effects
  • If pain persists after five days, consult a doctor for alternative medications
  • Do not exceed 40 milligrams in 24 hours

Dosage

  • Tablet: 10 mg
  • Injection solution: 15 mg/ML, 30 mg/mL
  • Start with injection; tablets used if needed after eating/drinking
  • Total therapy duration: ≤5 days
  • Intravenous dose for adults: 15-60 mg; max daily dose: 60-120 mg
  • Oral dose after IV therapy: 1-2 tablets initially, followed by one tablet every 4-6 hours; max: 40 mg/day
  • The smallest dose for kidney failure patients or those over 65
  • Not approved for under 17 years of age

Missed Dose

  • Missing one or two-dose of Ketorolac won’t show any effect on your body. The skipped dose causes no problem. However, with some medications, it won’t work if you don’t take the dosage on time.
  • If you miss a dose, some sudden chemical change may affect your body.
  • In some cases, your doctor would advise you to take the prescribed medicine as soon as possible if you have missed the dose.

Overdose

  • Overdose of a drug can be accidental.
  • If you have taken more than the prescribed ketorolac tablets, there is a chance of getting a harmful effect on your body’s functions.
  • Overdose of a medicine can lead to some medical emergency.

Interactions:

  • Ketorolac can increase the risk of bleeding when taken with other medications that also cause bleeding.
  • Examples include antiplatelet drugs like clopidogrel and "blood thinners" like dabigatran/enoxaparin/ warfarin.

Storage

  • Direct contact with heat, air and light may damage your medicines. The exposure of medicine may cause some harmful effects.
  • The medicine must be kept in a safe place and out of children’s reach.
  • Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).

Additional advice:

  • Before taking Ketorolac, consult your Doctor.
  • If you experience any problems or side effects after taking Ketorolac, rush immediately to your nearest hospital or consult your doctor for better treatment.
  • Always carry your medications in your bag while travelling to avoid any immediate emergencies.
  • Follow your prescription and follow your Doctor's advice whenever you take Ketorolac.

Ketorolac vs Ibuprofen

Ketorolac Ibuprofen
Ketorolac belongs to the class of drugs called nonsteroidal anti-inflammatory drugs which are used for treating inflammation and pain. The medication is more effective than other NSAIDs which helps in reducing pain from both inflammatory and non-inflammatory causes. ibuprofen is used for relieving the symptoms of arthritis, fever and menstrual; and other types of pain.
Ketorolac is used for short-term treatment of moderate to very severe pain the adults. The medication is usually used before and after medical procedures or after any surgery. Reducing pain helps in recovering more comfortably so that a person returns to its normal activities. The medication is used for prevention of some conditions like headache, dental pain, menstrual cramps and muscle aches.
Some of the serious side effects of Ketorolac are:
  • Fever
  • Blisters
  • Abnormal weight gain
  • Swelling of abdomen and ankles
  • Yellowing of the skin
  • Tiredness
  • Lack of energy
Most common side effects of Ibuprofen are:
  • Diarrhea
  • Nausea
  • Vomiting
  • Dizziness
  • Edema

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Frequently Asked Questions

Ketorolac is used for short-term treatment of moderate to very severe pain the adults. The medication is usually used before and after medical procedures or after any surgery. Reducing pain helps in recovering more comfortably so that a person returns to normal activities.

Ketorolac is not used for any minor or chronic conditions. Other NSAIDs also include Ibuprofen and Naproxen, but Ketorolac is much more effective than NSAIDs.

Ketorolac starts working very quickly within 15 minutes and its effect lasts up to 6 hours. The tablets are often prescribed for post-surgeries or severe migraines.

Some of the serious side effects of Ketorolac are fever, blisters, abnormal weight gain, swelling of the abdomen and ankles, tiredness and Lack of energy.

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