Overview of Ketotifen

Ketotifen is an antihistamine that reduces the effects of the body's natural chemical histamine, which can cause symptoms like sneezing, itching, watery eyes, and a runny nose. It is available as an ophthalmic solution (for the eyes) to relieve itching caused by allergies to dust, pollen, pets, or other allergens. Additionally, Ketotifen is used as an asthma medication in combination with other antiasthma drugs to reduce the frequency, severity, and duration of asthma attacks in children.

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Ketotifen Uses

  • Allergic/Seasonal Conjunctivitis: Prevents and treats itching in the eyes caused by allergies.
  • Asthma: Long-term medication for children to avoid or reduce wheezing and troubled breathing, used in conjunction with other asthma drugs like corticosteroids and inhaled beta-agonists.

How Ketotifen Works

  • Antihistamine Effect: Blocks histamine, a natural substance that causes allergic symptoms.
  • Mast Cell Stabilizer: Prevents the release of natural compounds that cause allergic reactions and reduces inflammation, airway spasms, and other asthma and allergy symptoms.

Ketotifen Side Effects

Common side effects include:


Precautions

  • Allergies: Inform your doctor if you are allergic to Ketotifen or any related medications.
  • Medical History: Inform your doctor of any eye problems, itching, irritation, or lung diseases.
  • Vision: May cause temporary blurred vision. Avoid driving or operating machinery until vision is clear.
  • Children: Not recommended for children under three without a doctor's advice.

How to Use Ketotifen

Oral Administration:

  • Take twice a day.
  • Tablets should not be crushed or chewed.
  • Take daily for safety and effectiveness.
  • Dosage may be increased gradually over the first week to reduce drowsiness.
  • Full effects may take several weeks (usually within 10 weeks).
  • Other asthma medications may be gradually reduced after 2-3 months of use.

Eye Drops:

  • Apply 1 drop to the affected eye(s) twice a day (every 8 to 12 hours) or as directed.
  • Follow instructions on the package or from your doctor.
  • Clean hands before use.
  • Do not touch the dropper tip to prevent contamination.
  • Remove contact lenses before use.
  • Apply 1 drop in the lower eyelid and close eyes gently for 1-2 minutes.

Missed Dose

If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose. Do not double the dose.


Overdose

An overdose of eye drops can cause severe side effects like headaches, eye irritation, and dry eyes. Contact a doctor immediately if an overdose is suspected.


Warnings for Serious Health Conditions

Pregnancy Breastfeeding:

  • Discuss with your doctor if you are pregnant. Use only if the benefits outweigh the risks.
  • Ketotifen eye drops generally have no side effects during breastfeeding, but consult a doctor before use.

Storage

  • Store at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Keep away from heat, air, and light.
  • Store in a safe place out of reach of children.

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Ketotifen vs. Olopatadine

Ketotifen Olopatadine
Used to prevent and treat allergic/seasonal conjunctivitis. Available as ophthalmic solutions (Pazeo, Patanol, Pataday).
It works by blocking histamine and stabilizing mast cells. Treats allergic conjunctivitis (pink eye).
Common side effects: Headache, runny nose, eye irritation. Common side effects: Blurred vision, stinging, dry eye.

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Frequently Asked Questions

1. What is Ketotifen used for?

This drug is used to prevent and treat allergic/seasonal conjunctivitis, which causes scratching in the eyes. Ketotifen is an antihistamine for the eyes that works by blocking a natural product that causes allergic symptoms (histamine).

2. When should I take Ketotifen?

If you are using ketotifen eye drop then follow your doctor’s advice. Apply 1 drop to the affected eye(s) twice a day (every 8 to 12 hours) or as instructed by your doctor or follow the package instructions. Dosage is determined by your medical condition and treatment reaction. Before applying eye drops, make sure your hands are clean.

3. How long does it take ketotifen to work?

It can take several weeks for the full effects of this medication to become apparent (usually within 10 weeks). Your doctor may gradually reduce the use of other asthma medications after 2 to 3 months of using this drug. Follow the doctor's instructions.

4. What are the side effects of ketotifen?

Some of the common and major side effects of Ketotifen are: Headache, Runny nose, Burning or stinging of the eye, Dry eyes, Eye pain.

5. Is Ketotifen sedative?

Ketotifen is an antiasthma drug used to prevent asthma attacks. Its sedative effect is due to histamine H1-receptor antagonism, which is the main effect. In clinical asthma, ketotifen has no effect on the acute challenge, airway hyperresponsiveness, or clinical symptoms.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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