Overview of Linagliptin
Linagliptin is a prescription medication used primarily to treat type 2 diabetes. It is often combined with metformin in a single tablet or taken separately. Linagliptin belongs to the class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors, which help increase the amount of insulin in the body, thereby lowering blood sugar levels.
Uses of Linagliptin
- Type 2 Diabetes Management:
- Linagliptin is used alongside diet and other medications to help control blood sugar levels in patients with type 2 diabetes.
- It works by increasing the amount of certain natural substances that lower blood sugar when it is high.
- It can also be used in combination with insulin to treat diabetes.
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Get A Second OpinionSide Effects of Linagliptin
Common Side Effects:
- Diarrhea
- Decreased appetite
- Nausea
- Vomiting
- Itching
Serious Side Effects:
- Lactic Acidosis:
- Symptoms include weakness, muscle pain, breathlessness, stomach pain, diarrhea, and irregular heartbeat.
- Low Blood Sugar (Hypoglycemia):
- Symptoms include sweating, fast heart rate, and dizziness.
- Allergic Reactions:
- Symptoms include swelling of the face, trouble swallowing, and skin rash.
Precautions
- Allergies: Inform your doctor if you are allergic to Linagliptin or any other medications.
- Medical History: Discuss any medical conditions such as pancreatic disease, gallbladder stones, or heart failure.
How to Take Linagliptin
- Form: Linagliptin comes in tablet form.
- Dosage: Take once daily with or without food at the same time each day.
- Adherence: Follow the directions on the prescription label and ask your doctor if you have any questions.
Dosage
Brand in India: Jentadueto
Immediate-Release Oral Tablet:
- Linagliptin 2.5 mg/metformin 500 mg
- Linagliptin 2.5 mg/metformin 850 mg
- Linagliptin 2.5 mg/metformin 1,000 mg
Extended-Release Oral Tablet:
- Linagliptin 2.5 mg/metformin 1,000 mg
- Linagliptin 5 mg/metformin 1,000 mg
For Type 2 Diabetes:
- Adult dosage: 2.5 mg of linagliptin and 500 mg of metformin
- Maximum dosage: 5 mg of linagliptin and 2000 mg of metformin per day
Missed Dose
- Action: Take as soon as remembered unless it is close to the next dose.
- Avoid: Do not double the dose to catch up.
Overdose
- Risk: Overdosing can lead to harmful effects on your body. Seek medical assistance immediately in case of an overdose.
Warnings for Serious Health Conditions
- Kidney Disease: Severe kidney disease increases the risk of lactic acidosis and heart failure.
- Liver Problems: Your doctor will monitor your liver function before and during treatment.
- Low Levels of Vitamin B12: Linagliptin can reduce blood levels of vitamin B12.
- Pancreatitis: Linagliptin can cause or worsen pancreatitis.
Storage
- Conditions: Store at room temperature (68ºF to 77ºF or 20ºC to 25ºC).
- Safety: Keep away from heat, air, light, and out of reach of children.
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Book an AppointmentLinagliptin vs. Sitagliptin
|
Linagliptin |
Sitagliptin |
|---|---|
|
Contains linagliptin and metformin; used to lower blood sugar levels in type 2 diabetes patients. |
Comes in oral tablet form under the brand name Januvia; used to treat high blood sugar levels caused by type 2 diabetes. |
|
Common side effects: diarrhea, decreased appetite, nausea, vomiting, and itching. |
Common side effects: upset stomach, diarrhea, stomach cramps, upper respiratory infection, headache. |
Consult your doctor before starting Linagliptin and for any side effects or reactions you experience. Carry your medication while traveling and follow your doctor's advice closely for the best results in managing your diabetes.
