What is Linezolid?

Linezolid is an antibiotic that helps the body fight bacteria. This is an MAO inhibitor as well. Zyvox brand is the brand name of the product. The drug is used to treat bacterial infections such as pneumonia, skin infections, and infections that have become resistant to other antibiotics. The drug works by inhibiting bacterial growth.


Uses of Linezolid

Linezolid is used to treat serious bacterial infections. This works by stopping the growth of bacteria. These antibiotics treat only bacterial infections.

  • Pneumonia
  • Skin infections
  • Certain types of bloodstream infections

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Side Effects of Linezolid

Some of the common side effects of Linezolid are:

  • Diarrhea
  • Headache
  • Nausea
  • Vomiting
  • Stomach pain
  • Rashes
  • Itching
  • Dizziness
  • Irritation

Some of the serious side effects of Linezolid are:

  • Hives
  • Blistering or peeling of skin
  • Pain
  • Numbness
  • Unusual bleeding
  • Bruising
  • Change in color & vision
  • Seizures

Linezolid can cause some serious side effects and can lead to some serious health problems. Suppose you are facing any of the above serious side effects. Talk with your doctor if you are having any serious problems.


Precautions To Follow

Before taking Linezolid, talk with your doctor if you are any allergic to it or any other medications related to it or if you have any medical history such as:

  • High blood pressure
  • Blood/ bone marrow problems
  • Thyroid
  • Seizures

Talk to your doctor if you are taking or planning to take any prescription or non-prescription medicines, vitamins, nutritional supplements, or herbal products.


How to use Linezolid?

  • Linezolid is available as a tablet or oral suspension.
  • Take it orally twice daily for 10 to 28 days, with or without food.
  • Children under 11 take it 2 to 3 times daily.
  • Gently mix the oral suspension before use.
  • Complete the prescribed course even if symptoms improve.
  • Adult dose for pneumonia or skin infections: 600 mg orally or intravenous every 12 hours for 10 to 14 days.

Missed Dose

  • As soon as you remember, take the missing dose.
  • If it's time for the next dose, skip the missed dose and return to your normal dosing schedule.
  • To make up for a missed dose, do not take a double dose as it will lead to severe adverse effects.

Overdose

  • Overdose of the medications will show various side effects like vomiting, nausea and diarrhea.
  • In any case, if you have taken an overdose of medication then talk to your doctor immediately.

Warnings for Serious Health Conditions

Pregnancy & Breastfeeding

Linezolid's effects in pregnant or breastfeeding women aren't well-studied. Consult your doctor before use to avoid potential risks to infants.


Storage Instructions

  • Direct contact with heat, air and light may damage your medicines.
  • Exposure to medicine may cause some harmful effects.
  • The medicine must be kept in a safe place and out of children’s reach.
  • Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).

Linezolid vs Ceftriaxone

Linezolid Ceftriaxone
Linezolid is an antibiotic that helps the body fight bacteria. This is an MAO inhibitor as well. Zyvox brand is the brand name of the product. Ceftriaxone is a cephalosporin antibiotic. This medication is used to treat a variety of bacterial infections, including those that are serious or life-threatening, such as E. coli, pneumonia, or meningitis
Linezolid is an antibiotic that is used for the treatment of serious bacterial infections. This works by stopping the growth of bacteria. Ceftriaxone injection is used for the treatment of meningitis, gonorrhoea, pelvic inflammatory disease, meningitis, and infections of the lungs, ears, skin, urinary tract and blood.
Some of the common side effects of Linezolid are:
  • Diarrhea
  • Headache
  • Nausea
  • Vomiting
  • Stomach pain
Some of the common side effects of Ceftriaxone are:
  • Rash
  • Watery stools
  • Stomach cramps
  • Pain
  • Bloating
  • Nausea

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Frequently Asked Questions

Linezolid is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria. These antibiotics treat only bacterial infections.

In the treatment of skin and soft tissue infections (SSTIs) caused by Gram-positive bacteria, linezolid was found to be more effective than glycopeptide antibiotics (such as vancomycin and teicoplanin) and beta-lactam antibiotics in a large meta-analysis of randomised controlled trials.

Linezolid belongs to the class of medication called MAO inhibitors. This will increase the level of certain natural substances in the body that can increase the chance of various side effects and drug interactions.

Some of the common side effects of Linezolid are diarrhea, headache, nausea, vomiting and stomach pain.

Linezolid is available as a tablet and an oral suspension (liquid) for oral administration. It's normally taken twice a day (every 12 hours) for 10 to 28 days, with or without food. Children who are 11 years of age or younger usually take the medication with or without food 2 to 3 times a day, at least for 10 to 28 days.

Due to a lack of effective oral therapy options, urinary tract infections (UTIs) caused by vancomycin-resistant enterococcus (VRE) are difficult to handle. Linezolid is a VRE-fighting antibiotic that can be taken orally, but only about 30% of each dose is excreted in the urine.

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