What is Loperamide?

Loperamide is a medication used for the relief of acute diarrhea and the management of chronic diarrhea in patients with inflammatory bowel disease. Its efficacy is comparable to that of another anti-diarrheal, diphenoxylate (Lomotil). Loperamide helps reduce diarrhea by slowing the movement of the bowel muscles. Although loperamide is chemically related to narcotics like morphine, it has no pain-relieving effects, even at high doses.

Loperamide Uses

Loperamide is used to treat diarrhea by slowing down the movement of the gut. This decreases the number of bowel movements and makes stools less watery. It's also used to reduce discharge in patients who have undergone an ileostomy and to treat ongoing diarrhea associated with inflammatory bowel disease.

Secure your health with a second opinion. Make informed decisions and book your appointment today!

Get A Second Opinion

Side Effects

Common Side Effects:

Constipation
Fatigue

Major Side Effects:

Rash
Peeling
Blistering skin
Hives
Itching
Wheezing
Difficulty breathing
Fever
Stomach pain
Swelling
Bloody stools

If you experience any serious symptoms, contact your doctor immediately. Most people do not experience side effects, but seek medical help if you do.

Precautions

Before taking loperamide, inform your doctor if you are allergic to it or other medications. This product may contain inactive ingredients that can cause allergic reactions.
Do not use this medication if you have certain medical conditions. Consult your doctor if you have:
- Stomach pain
- Abdominal pain
- Bowel obstruction

How to Take Loperamide

Loperamide is available as a tablet, capsule, and liquid to be taken orally. Non-prescription loperamide is usually taken after each loose bowel movement and should not exceed the maximum 24-hour dosage on the label. Prescription loperamide may be taken on a schedule as advised by your doctor.

Dosage for Loperamide

Adult Dosage:

Initial dose: 4 mg followed by 2 mg per loose stool
Maximum daily dose: 16 mg (8 mg if self-medicating)
Chronic diarrhea: 4-8 mg per day after control is achieved

Children:

Acute Diarrhea:
- Age 8 to 12 years: 2 mg three times a day
- Age 6 to 8 years: 2 mg twice a day
Chronic Diarrhea:

Missed Dose

Missing one or two doses of loperamide typically doesn't cause any issues. However, take the missed dose as soon as you remember unless it's near the time for the next dose. Do not double the dose.

Overdose

An overdose of loperamide can cause serious effects. If you suspect an overdose, seek medical attention immediately.

Pregnancy and Breastfeeding

There are no adequate studies on loperamide in pregnant women, but animal studies with high doses have not shown significant adverse effects on the fetus. Doctors may recommend loperamide during pregnancy if the benefits outweigh potential risks.

Ready to take control of your health journey? Book your appointment now and start your path towards wellness today!

Book an Appointment

Storage

Store at room temperature (68°F 77°F / 20°C 25°C)
Keep away from heat, air, and light
Keep out of reach of children and pets
Properly dispose of expired or unused medication

Loperamide vs Dicyclomine

Loperamide	Dicyclomine
Used for the relief of acute diarrhea and management of chronic diarrhea in patients with inflammatory bowel disease.	Belongs to the anticholinergics class, used to relieve muscle spasms in the gastrointestinal tract by blocking the activity of certain natural substances.
Slows down gut movement, decreasing the number of bowel movements and making stools less watery.	Used to treat irritable bowel syndrome, reducing stomach and intestinal cramps.
Major Side Effects: Rash Peeling Blistering skin Hives Itching	Serious Side Effects: Coma Anxiety Muscle weakness Hives Fainting

Citations

Loperamide

Book Doctor Appointment

Name*

Mobile Number*

I agree to the Medicover Privacy Policy

International Patient Services

Frequently Asked Questions

1. Is loperamide an antibiotic?

Loperamide is an anti-diarrheal medication, not an antibiotic. It is used for the treatment of diarrhea by slowing down the movement of the bowel muscles.

2. How many times a day should I take loperamide?

In adults and children 12 years of age and older, the recommended dosage is initially 4 mg followed by 2 mg per loose stool. The maximum daily dose is 16 mg per day (8 mg if self-medicating).

3. What are the side effects of loperamide?

Some of the major side effects of loperamide include rash, peeling, blistering skin, hives, itching, and wheezing.

4. Can I take loperamide on an empty stomach?

Loperamide tablets can be taken with or without food. It is advisable to consult with your doctor before taking loperamide.

5. What drugs does loperamide interact with?

Drugs that can interact with loperamide include pramlintide. Additionally, drugs that can cause constipation, such as ritonavir, saquinavir, and cholestyramine, may also interact with loperamide.

6. Does loperamide make you sleepy?

An overdose of loperamide can cause drowsiness. Consult with your doctor if you experience this side effect.

7. Is loperamide safe to take daily?

Loperamide should be taken as directed by your doctor. It is important to discuss with your doctor before taking loperamide on a daily basis.

Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.