What is Lycopene?

Lycopene is a plant nutrient known for its antioxidant properties. It is the pigment responsible for the red and pink colors in fruits such as tomatoes, melons, and pink grapefruit. Lycopene has been associated with various health benefits, including heart health, sunburn protection, and potential protection against certain types of cancer.

Benefits of Lycopene

Sources of Lycopene in Nature

  • Lycopene is a naturally occurring chemical classified as a carotenoid pigment.
  • It is predominantly found in tomatoes, red oranges, melons, pink grapefruit, apricots, rosehips, and guava.
  • In North America, about 85% of dietary lycopene comes from tomato products like ketchup, tomato juice, sauce or paste.
  • Fresh tomatoes contain between 4 mg and 10 mg of lycopene.
  • A cup (240 mL) of tomato juice provides approximately 20 mg of lycopene.
  • Cooking tomatoes with heat (e.g: making juice, sauce, or ketchup) transforms the lycopene into a more bioavailable form for the body.

Antioxidant Benefits of Lycopene

  • Lycopene belongs to the carotenoid family and acts as a potent antioxidant.
  • Antioxidants protect the body from damage caused by free radicals.
  • Free radicals can lead to oxidative stress and various chronic diseases such as cancer, diabetes, heart disease, and Alzheimer's.
  • Research suggests that lycopene's antioxidant effects help maintain a balanced level of free radicals in the body.
  • This offers protection against these conditions.
  • Studies indicate that lycopene may shield the body from certain environmental toxins like pesticides, herbicides, and monosodium glutamate (MSG).

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Lycopene's Role in Cancer Prevention

  • Lycopene's antioxidant properties may prevent or slow down certain cancers.
  • Test tube studies suggest lycopene can inhibit breast and prostate cancer cell growth.
  • Animal studies indicate potential protective effects against kidney cancer.
  • Observational studies link higher carotenoid intake, including lycopene, to a reduced risk (32–50%) of lung and prostate cancer.
  • Men consuming two or more servings of lycopene-rich tomato sauce per week had a 30% lower risk of prostate cancer compared to those with less than one serving per month.
  • Recent reviews suggest a more modest 9% lower risk of prostate cancer with higher lycopene intake.
  • Daily intake of 9–21 mg of lycopene per day appears particularly beneficial.

Cardiovascular Benefits of Lycopene

Lycopene may lower your risk of heart disease and premature death by reducing risk factors such as free radical damage and cholesterol levels:

  • Reduces Risk Factors: Lycopene lowers "bad" LDL cholesterol and increases "good" HDL cholesterol, which can benefit heart health.
  • Lower Mortality Risk: Individuals with higher blood lycopene levels have up to a 39% lower risk of premature death over a 10-year period.
  • Decreases Heart Disease Risk: Diets rich in lycopene are associated with a 17-26% lower risk of heart disease.
  • Protects Against Stroke: High blood levels of lycopene are linked to a 31% lower risk of stroke, especially beneficial for those with low antioxidants or high oxidative stress.

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Additional Health Benefits of Lycopene

Lycopene offers additional health benefits:

  • May Help Eyesight: Prevents cataracts and reduces the risk of macular degeneration.
  • Reduces Pain: Helps alleviate neuropathic pain and tissue damage.
  • Protects Brain Function: Antioxidant properties may prevent seizures and memory loss in conditions like Alzheimer's.
  • Contributes to Bone Health: Slows bone cell death, strengthens bone structure, and supports overall bone health.

Lycopene Side Effects

Lycopene is generally safe when taken orally in appropriate amounts:

  • Safety: Daily supplements up to 120 mg for a year have shown no reported side effects.

Precautions

  • Pregnancy and Breastfeeding: Lycopene from food sources is safe, but avoid high-dose supplements during pregnancy and breastfeeding due to potential risks of premature births or low birth weight.
  • Surgery: Discontinue lycopene supplements at least two weeks before surgery to prevent increased bleeding risk.

Food Sources

Natural foods with rich pink to red colors are excellent sources of lycopene:

  • Tomatoes: Ripe tomatoes are the highest source of lycopene.
  • Other Sources: Includes sun-dried tomatoes, guava, papaya, pink grapefruit, and cooked sweet red peppers.

Recommended Intake

There's no official daily recommendation, but intakes between 8–21 mg per day are shown to be beneficial based on current studies.

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Frequently Asked Questions

1.What is Lycopene used to treat?

Lycopene suggested uses include cancer, prevention of atherosclerosis, cardiovascular disease, prostate cancer, human papillomavirus (HPV) infection, cataracts, asthma, antioxidants, and anti-inflammatory drugs.

2. Why is Lycopene bad for you?

When consumed in food, lycopene is safe for everyone to eat. Eating excessive amounts of lycopene may lead to a condition called lycopenemia, which is orange or red skin discoloration. The condition itself is harmless and goes away by eating a lower lycopene diet.

3. Is Lycopene bad for kidneys?

Lycopene and vitamin C have been shown to have an influence on oxidative stress and inflammation biomarkers. Low plasma levels of lycopene and analgesic intake may increase the risk of CKD.

4. What is the best source of Lycopene?

Lycopene makes tomatoes red and gives color to other orange fruits and vegetables. Processed tomatoes have the highest lycopene content, but watermelon, pink grapefruit and fresh tomatoes are also good sources.

5. Is lycopene good for your prostate?

Tomatoes contain a potent antioxidant called lycopene. It may help prevent cancer of the prostate as well as reduce tumor growth among people with prostate cancer.

6. Does Lycopene increase testosterone?

Evidence suggested that tomato or lycopene intake may modulate testosterone production, serum concentrations, and metabolism, and may affect gene expression in human prostate cancer cells, normal rat prostate, and established xenografts of prostate cancer (7–10).


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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