What is Medroxyprogesterone?
Medroxyprogesterone injection is a prescription drug available under brand names like Depo-Provera, Depo-Provera CI, or Depo-subQ Provera 104. It is a progestin that helps regulate ovulation and menstrual cycles in women. The medication treats irregular or missing menstrual cycles, abnormal uterine bleeding, and reduces the risk of endometrial hyperplasia during estrogen hormone replacement therapy in postmenopausal women.
Medroxyprogesterone Uses
Medroxyprogesterone is a progestin hormone used for:
- Treating irregular uterine bleeding.
- Restoring regular menstrual cycles in women with amenorrhea.
- Managing menopause symptoms in combination with estrogen therapy.
Medroxyprogesterone Side Effects
Common side effects may include:
Serious side effects can include:
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Precautions Before Using Medroxyprogesterone
Before using Medroxyprogesterone, inform your doctor if you:
- Are allergic to it or any other medications.
- Have a history of blood clots, internal bleeding, liver disease, cancer, vaginal bleeding, or seizures.
- Discuss potential risks with inactive ingredients in the medication.
How to Use Medroxyprogesterone injection
- Administered intramuscularly into the buttocks or upper arm by a healthcare provider every 13 weeks.
- Subcutaneous injection available for administration just under the skin every 12 to 14 weeks.
- For menstrual cycle management, take once daily for 5-10 days during the second half of the cycle, as directed by your doctor.
Withdrawal bleeding typically occurs 3-7 days after stopping the medication.
Dosage Instructions for Medroxyprogesterone
Missed Dose:
- Missing one or two doses of medroxyprogesterone won't typically affect your body. However, consistent timing is important for the medication to work effectively. Missing a dose may cause sudden chemical changes in your body.
Overdose:
- Accidentally taking more than the prescribed medroxyprogesterone tablets can have harmful effects on your body's functions and may lead to a medical emergency.
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Medroxyprogesterone Warnings for Health Conditions
For People with Blood Clots or Stroke:
Medroxyprogesterone increases the risk of blood clots. If you have a history of blood clots or stroke, consult your doctor before using this medication.
For People with Liver Problems:
Liver disorders can affect how medroxyprogesterone is processed in your body, potentially increasing its levels and leading to more side effects. Discuss with your doctor if you have liver problems or a history of liver disease.
Pregnant Women:
Medroxyprogesterone should not be used during pregnancy. If you become pregnant while taking this medication, contact your doctor immediately.
Breastfeeding:
Medroxyprogesterone can pass into breast milk and may cause problems for a breastfed infant. Consult your doctor if you are breastfeeding; you may need to stop breastfeeding or adjust your medication.
Storage Information
- Store medroxyprogesterone at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
- Keep the medication in a safe place, protected from heat, air, and light to avoid potential damage.
- Ensure the medicine is stored out of children's reach to prevent accidental ingestion.