What is Nabumetone?

Nabumetone is a nonsteroidal anti-inflammatory medication sold under various brand names, including Relafen, Relifex, and Gambaran.

The medication is a nonacidic nonsteroidal anti-inflammatory drug that is rapidly metabolized in the liver to the active metabolite, 6-methoxy-2-naphthyl acetic acid.

Nabumetone Uses

Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) used to treat arthritis pain, swelling, and joint stiffness.

If you have a chronic condition like arthritis, talk to your doctor about non-drug treatments or other medications for pain.

How to use Nabumetone?

Before you start to use nabumetone, and each time you get a refill, read the Medication Guide provided by your pharmacist.
Take this medication orally, usually once or twice daily, with a full glass of water, as directed by your doctor.
After taking this medication, do not lie down for at least 10 minutes. To avoid stomach upset, take it with food, milk, or an antacid.
When taking this medication on a regular basis, it may take up to two weeks before you notice the full benefits in certain conditions (such as arthritis).
If you take this medication on a needed basis rather than on a regular basis, keep in mind that pain medications work best when taken as soon as the first signs of pain appear.
If you wait until the pain has become unbearable, the medication may not be as effective.

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Side Effects

Some of the common side effects of Nabumetone are:

Diarrhea
Constipation
Gas or bloating
Dizziness
Headache
Dry mouth
Sores in the mouth
Nervousness
Difficulty falling asleep or staying asleep
Increased sweating
Ringing in the ears

Some of the severe side effects of Nabumetone are:

Unexpected weight gain
Shortness of breath or difficulty breathing
Yellowing of the skin or eyes
Lack of energy
Loss of appetite
Nausea

Precautions

Inform your doctor if you are allergic to nabumetone, aspirin, or other NSAIDs or if you have other allergies.
Share your medical history with your doctor, especially if you have asthma, bleeding/clotting issues, nasal growths, heart disease, high blood pressure, liver disease, stroke, or stomach/intestinal/esophageal problems.
NSAIDs like nabumetone can cause kidney problems. Drink plenty of fluids to avoid dehydration, and notify your doctor if your urine output changes.
This medication can cause stomach bleeding. Regular use of alcohol and tobacco can increase this risk.
Older adults may be more likely to experience stomach bleeding, kidney problems, heart attack, or stroke while taking this medication.
Inform your doctor if you are pregnant. Nabumetone is not recommended during pregnancy, especially from 20 weeks until delivery, due to potential harm to the unborn baby and complications during labour.
It is unclear if nabumetone passes into breast milk. Consult your doctor before breastfeeding.

Interactions

Drug interactions can affect the way your medications work or put you at risk for serious side effects. Aliskiren, ACE inhibitors, angiotensin II receptor blockers, cidofovir, corticosteroids, lithium, methotrexate, and water pills are some products that may interact with this medication.

When combined with other drugs that may cause bleeding, this medication may increase the risk of bleeding. Antiplatelet drugs such as clopidogrel and blood thinners such as dabigatran/enoxaparin/warfarin are examples.

Missed Dose

It is necessary to take each dose of this medication on time. If you forget a dose, contact your doctor or pharmacist as soon as possible to arrange for a new dosing schedule. Do not double the dose.

Overdose

If someone has taken an overdose of this medicine and has serious symptoms such as trouble breathing, seek medical advice immediately. Never take more doses than what is prescribed to you by your doctor.

Storage

The medicine must not come in contact with heat, air, light and may damage it. The medicine must be kept in a safe place and far away from children’s reach.

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Nabumetone vs Ibuprofen

Nabumetone	Ibuprofen
Nabumetone is a type of nonsteroidal anti-inflammatory medication. It is sold under a variety of brand names, including Relafen, Relifex, and Gambaran.	Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used as a common pain reliever used to treat a variety of aches and pains.
It is used to treat arthritis pain, swelling, and joint stiffness.	It is used to treat pain, fever, back pain, period pain, and toothache. It is also used to treat inflammation, such as strains and sprains, as well as arthritis pain.
It works by blocking the production of chemicals in your body that cause inflammation and pain.	Ibuprofen works by lowering hormones in the body that cause pain and swelling.

Citations

Nabumetone

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Frequently Asked Questions

1. Is nabumetone stronger than ibuprofen?

After 12 weeks of treatment, researchers discovered that nabumetone was as effective as ibuprofen and other NSAIDs in treating osteoarthritis as ibuprofen and other NSAIDs.

2. What do you use nabumetone for?

Nabumetone is used for treating the pain, swelling, and stiffness associated with osteoarthritis and rheumatoid arthritis.

3. Does nabumetone work right away?

Nabumetone usually starts working within a week, but in severe cases, it may take up to two weeks or longer before you start feeling better. Furthermore, it may take several weeks before you feel the full effects of nabumetone.

4. Does nabumetone cause weight gain?

Yes, it may cause weight gain because it is one of its side effects.

5. Is nabumetone bad for the liver?

Since its approval and release, nabumetone has been linked to a small number of serious hepatic adverse events (1.3 per million prescriptions), but no cases of clinically apparent liver injury due to nabumetone have been reported in the literature.

6. How long does it take for nabumetone to kick in?

This medication usually starts working within a week, but in severe cases, it may take up to two weeks or longer before you start feeling better.

7. Is nabumetone an anti-inflammatory?

Yes, Nabumetone is used to treat arthritis pain, swelling, and joint stiffness.

8. How long can you safely take nabumetone?

When used to treat severe or ongoing arthritis, this medication must be taken on a regular basis as directed by your doctor in order to be effective. This medication usually starts working within a week, but in severe cases, it may take up to two weeks or longer before you start feeling better.

9. Does nabumetone raise blood pressure?

Nabumetone treatment resulted in a moderate increase in both daytime and nighttime blood pressure, with no changes in biological diurnal variation.

10. Can I drink alcohol while taking nabumetone?

Avoid consuming alcoholic beverages. It will raise your chances of experiencing stomach bleeding. While taking nabumetone 500mg, avoid taking aspirin. Before taking any other pain medications, fever, swelling, or flu symptoms, consult your doctor.

Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.