What is Orphenadrine?

Orphenadrine is available only as a prescription drug. It comes as an extended-release oral tablet, which slowly releases the drug into the bloodstream. This treatment is often given as an intravenous (IV) injection and an intramuscular (IM) injection by a healthcare provider only.

Orphenadrine's oral tablet is available as a generic drug only. It is often used to relieve muscle pain in musculoskeletal disorders, for rest, physical therapy, and other therapies.


Orphenadrine Uses

Orphenadrine belongs to a class of drugs called relaxants of the skeletal muscle. It functions by adjusting the way muscle pain is felt by the body. This medication is an oral skeletal muscle relaxant with a central action that is used to treat acute muscle aches, discomfort, or spasms.

The precise mechanism of action for relieving muscle aches or spasms is not fully known. This medication can reduce muscle spasms by acting on the motor centers of the medulla in the brain.

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Orphenadrine Side Effects

Some of the common side effects are:

Some of the serious side effects are:

If you have any of these serious symptoms, immediately contact your doctor for further assistance. In any case, due to this medication, if you get any kind of reaction in your body, try avoiding it.

A doctor advised you to take the medicines after seeing your problems and the benefits of this medicine, which are greater than the side effects. The majority of the people who use this medicine don’t show any side effects. Get medical help immediately if you get any serious side effects.


Precautions

Before taking it, talk with your doctor if you are allergic to it or any other medications. The product may contain inactive ingredients, which can cause serious allergic reactions and disorders in the body.

Before taking this medication, talk with your doctor if you have any medical history, such as:

  • Glaucoma
  • Esophagus problems
  • Difficulty while urinating
  • Certain types of muscle or Nerve diseases
  • Heart problems

How to take Orphenadrine?

Orphenadrine comes as a tablet and a (long-acting) extended-release tablet. It is normally taken twice on a daily basis. Try taking this medication at about the same time every day. This should be taken orally, as prescribed by the doctor, with or without food. Do not increase the dose of this drug or use it more frequently or longer than required. It will not improve your condition any sooner, and it will raise your risk of side effects.


Dosage

Dosage for muscle pain

Generic:

Orphenadrine

Form:

oral tablet (100 mg)

Adult dosage (ages 18 years and older):

Typically starting dosage: 200 mg per day (100 mg tablet in the morning and 100 mg tablet in the Evening)


Missed Dose

Missing one or two doses won’t have any effect on your body. The skipped dose causes no problem. However, with some medications, it won’t work if you don’t take the dosage on time. If you miss a dose, some sudden chemical change may affect your body. In some cases, your doctor would advise you to take the prescribed medicine as soon as possible if you have missed the dose.

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Overdose

Overdose of a drug can be accidental. If you have taken more than the prescribed tablets, there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.


Warnings for some Serious Health Conditions

Overdose of a drug can be accidental. If you have taken more than the prescribed tablets, there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.

For people with Heart Problems

If you have heart disease, decreased blood flow to your heart, or a rapid or irregular heart rate, ask your doctor if this drug is appropriate for you. Your condition can be made worse by this medicine.

For people with Eye problems

This medicine can increase blood pressure in the eyes. If you have glaucoma, you cannot use this drug; it will worsen your glaucoma. Before taking this prescription, inform your doctor if you have a history of eye problems.

For people with Stomach problems

If you have any kind of ulcers or another blockage in your digestive tract, you shouldn't take this drug. If you have a history of stomach issues, tell your doctor. If this medication is safe for you, your doctor will determine.


Storage

Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach.

Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).

Before taking Orphenadrine, consult your Doctor. If you face any problems or get any side effects after taking Orphenadrine, rush immediately to your nearest hospital or consult your doctor for better treatment. Carry your medications in your bag while travelling to avoid any immediate emergencies. Follow your prescription and follow your Doctor's advice whenever you take it.


Orphenadrine vs. Cyclobenzaprine

Orphenadrine Cyclobenzaprine
The medication is available only as a prescription drug. This comes as an extended-release oral tablet. An extended-release tablet will slowly release the drug into the bloodstream. Cyclobenzaprine is used to relax the muscles and reduce pain and irritation caused by strains, sprains, and other muscle injuries through rest, physical therapy, and other interventions.
This medicine belongs to a class of drugs called relaxants of the skeletal muscle. It functions by adjusting the way muscle pain is felt by the body Cyclobenzaprine is part of a class of drugs called relaxants of the skeletal muscle. It works to encourage the muscles to relax by working on the brain and nervous system
Some of the common side effects are:
  • Dry mouth
  • Drowsiness
  • Dizziness
  • Upset stomach
  • Vomiting
Most of the common side effects of Imodium are:
  • Dry mouth
  • Dizziness
  • Nausea
  • Constipation
  • Heartburn

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Frequently Asked Questions

1. What kind of drug is orphenadrine?

Orphenadrine belongs to a class of drugs called relaxants of the skeletal muscle. It functions by adjusting the way muscle pain is felt by the body.

2. Is Orphenadrine a painkiller?

Orphenadrine is a mixture of a muscle relaxant, a pain reliever and caffeine that improves the pain-relieving effects of the other medications used to treat injuries and other painful muscle conditions together with rest and physical therapy.

3. Will Orphenadrine make me sleepy?

Orphenadrine oral tablets can cause drowsiness and other side effects may also be caused.

4. How does Orphenadrine make you feel?

There might be dry mouth, dizziness, sleepiness, lightheadedness, blurred vision, nausea, throwing up, and constipation. Tell your physician or pharmacist immediately if any of these symptoms persist or worsen.

5. How long does Orphenadrine take to work?

Orphenadrine has a 1-hour onset of action after oral administration. The onset of action is approximately 5 minutes after IM injection and with IV administration almost instantly. The plasma half-life of the drug is 14 hours with a 4 to 6-hour period of action.

6. Is Orphenadrine an anti-inflammatory?

To generate its muscle relaxant effects, orphenadrine works in the central nervous system (CNS). Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief and fever control.

7. What is Orphenadrine citrate paracetamol used for?

Orphenadrine citrate paracetamol combination medications are used for the treatment of moderate to severe pain associated with muscle spasms.

8. Is Orphenadrine available in different forms, such as injections?

Yes, Orphenadrine is available in different forms, including tablets and injections. The form prescribed to you will depend on your condition and the healthcare provider's recommendation.

9. Can I drink alcohol while taking Orphenadrine?

It is advisable to avoid alcohol while taking Orphenadrine, as it can increase the risk of side effects such as dizziness and drowsiness.

10. What should I do if I miss a dose of Orphenadrine?

If you miss a dose of Orphenadrine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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