Perampanel: Usage, Side Effects, and Precautions
Perampanel is used for treating certain kinds of partial-onset seizures in adults and children who are 4 years of age and older. It is also used in conjunction with other medications to treat certain types of primary generalized tonic-clonic seizures in adults and children aged 12 and up.
How to Use Perampanel
- Perampanel is available as a tablet and a suspension (liquid) for oral administration.
- It is usually taken at bedtime once a day. Follow the instructions on your prescription label carefully.
- Before each use, shake the suspension well to ensure the drug is evenly distributed.
- Use the oral dosing syringe that comes with perampanel suspension. Do not use a regular spoon.
- Your doctor will most likely start you on a low dose and gradually increase it once a week or less.
- Perampanel can become addictive. Do not take a higher dose or take it more frequently than prescribed.
- Perampanel helps manage your condition but won’t cure it. Do not stop taking it without consulting your doctor. Stopping suddenly can worsen seizures.
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Get A Second OpinionPerampanel Side Effects
- Dizziness
- Sense of spinning
- Drowsiness
- Constipation
- Nausea
- Vomiting
- Headache
- Tiredness
- Weight gain
- Irritability
- Weakness
- Problems with coordination
- Muscle pain or joint pain
- Back pain
- Decreased sense of touch or sensation
- Blurred vision
Precautions for Perampanel
- Allergies: Inform your doctor if you are allergic to perampanel or have any other allergies.
- Medical Conditions: Inform your doctor if you have liver problems, kidney problems, mental/mood disorders, or galactose intolerance.
- Pregnancy: This medication should not be taken during pregnancy as it can harm the unborn child. However, untreated seizures can also harm both the mother and the child. Consult your doctor about the benefits and risks.
- Breastfeeding: This drug does not appear to pass through breast milk. Consult your doctor before breastfeeding.
Dosage Instructions
- Inform your doctor about all the medications you are taking to avoid interactions.
- May interact with the perampanel.
- This medication may reduce the effectiveness of birth control pills containing levonorgestrel. Consult your doctor about using non-hormonal backup birth control while taking perampanel and for a month after stopping it.
Missed Dose
- If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose. Do not double the dose.
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Book an AppointmentOverdose
- If someone has overdosed and has serious symptoms such as passing out or trouble breathing, seek medical attention immediately. Never take more than the prescribed dose.
Storage
- Store the medicine away from heat, air, and light to avoid damaging it. Keep it out of children’s reach.
- Liquid Form: Store below 86°F (30°C), do not freeze, and discard any unused liquid 90 days after first opening the bottle.
Perampanel vs Lacosamide
| Perampanel | Lacosamide |
|---|---|
| Perampanel (Fycompa) is an antiepileptic drug used in combination with other medications | Lacosamide belongs to the anticonvulsant medication class. It reduces brain's abnormal electrical activity. |
| Perampanel is used to prevent seizures. | Lacosamide is used to treat partial-onset seizures in adults and children aged 4 and up. |
| It is also used in combination with other medications to treat certain types of primary generalized tonic-clonic seizures in adults and in children more than 12 years of age. | In adults and children 4 years of age and older, lacosamide is used in conjunction with other drugs to treat primary generalized tonic-clonic seizures |
