What is Polymyxin?

Polymyxin B is a polymyxin antibiotic used to cure bacterial infections. It is ineffective against colds, measles, and other viral infections. The medication is mainly used to treat various infections, including urinary tract infections, meningitis, blood infections, and eye infections.


Polymyxin B Uses:

Polymyxin B is used to treat and prevent minor skin infections caused by small wounds, scrapes, or burns. It is not suitable for large areas of the body. Consult your doctor before using this medication for skin injuries or diseases. This product contains antibiotics neomycin, bacitracin, and polymyxin, which work by preventing bacteria from growing. It is only effective against bacterial skin infections and is ineffective against other types of skin infections (e.g., fungal or viral infections).

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Side Effects:

Common side effects of Polymyxin B include:

  • Burning sensation
  • Eye irritation
  • Pain
  • Redness
  • Swelling at the injection site
  • Flushing
  • Dizziness
  • Drowsiness
  • Fever
  • Headache
  • Back pain
  • Stiff neck
  • Unsteadiness
  • Hives
  • Rash

While under treatment, if side effects persist or worsen, contact your doctor immediately.


Precautions:

Before using Polymyxin B, inform your doctor if you are allergic to it or any related medications. The medication may contain inactive ingredients that can cause serious allergic reactions or other problems. Also, discuss your medical history with your doctor, especially if you have:

How to Use Polymyxin B?

Follow the directions on the product package or your doctor’s instructions. If you have any questions, consult your doctor or pharmacist. Clean and dry the infected area before applying the medication.

  • Ointment: Apply a small amount 1 to 3 times a day in a thin layer on the skin. Wash your hands before applying the ointment and after application.
  • Spray: Shake well before use. Spray a small amount on the affected area as directed, usually once or twice a day.

Do not use more than the recommended amount or for longer than directed. If advised otherwise by your doctor, do not use this product for more than one week. Avoid using on irritated skin in a child's diaper region unless instructed by a doctor.


Missed Dose:

If you forget to take a dose, use it as soon as you remember. If it's close to the next dose, skip the missed dose. Do not double the dose to make up for the missed one.


Overdose:

Symptoms of overdose may include stomach ache, nausea, and vomiting. If you suspect an overdose, contact your doctor immediately or go to the nearest hospital.


Warnings for Some Serious Health Conditions:

Pregnancy & Breastfeeding: This drug may harm an unborn child. Inform your doctor if you are pregnant or plan to become pregnant during treatment. It is unclear if Polymyxin B passes into breast milk. Consult your doctor if you are breastfeeding.


Storage:

Store Polymyxin B at room temperature between 68ºF and 77ºF (20ºC and 25ºC). Keep it away from direct contact with heat, air, and light. Ensure the medication is kept in a safe place and out of reach of children.

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Polymyxin B vs Colistin:

Polymyxin B Colistin
Polymyxin B is a polymyxin antibiotic used to treat bacterial infections. It is ineffective against viral infections like colds and measles. Colistin is an antibiotic used for serious bacterial infections that do not respond to other antibiotics.
Used to treat and prevent minor skin infections caused by small wounds, scrapes, or burns. Useful for treating stomach and intestine infections caused by sensitive gram-negative bacteria and for bowel sterilization before surgery.
Common Side Effects: Burning sensation, eye irritation, pain, redness, swelling at the injection site. Common Side Effects: Kidney damage, diarrhea, nausea, vomiting.
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Frequently Asked Questions

1. What is polymyxin B used for?

Polymyxin B is used to prevent or treat bacterial skin infections. It contains antibiotics (neomycin, bacitracin, and polymyxin) that work by preventing bacteria from growing.

2. How many drops of polymyxin B should I take for pink eye?

For ophthalmic (eye drop) use, one drop should be used in the affected eye(s) every 3 hours for 7 to 10 days in adults and children 2 months of age and older. Your doctor may advise more frequent use during serious infections.

3. What are the side effects of polymyxin B?

Common side effects of polymyxin B include burning sensation, eye irritation, pain, redness, and swelling at the injection site.

4. What bacteria does polymyxin B kill?

Polymyxin B has rapid bactericidal activity against multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae.

5. Is polymyxin B an antibiotic?

Yes, polymyxin B is a polymyxin antibiotic used to treat various infections including urinary tract infections, meningitis, bloodstream infections, and eye infections.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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