What is Ramelteon?
- Ramelteon, marketed under the brand name Rozerem, is a sleep agent medicine.
- It binds exclusively to the suprachiasmatic nucleus of the MT1 and MT2 receptors, unlike drugs such as zolpidem, which bind to GABAA receptors.
Secure your health with a second opinion. Make informed decisions and book your appointment today!
Get A Second OpinionReady to take control of your health journey? Book your appointment now and start your path towards wellness today!
Book an AppointmentRamelteon | Melatonin |
---|---|
Formula: C16H21NO2 | Formula: C13H16N2O2 |
Is a sleep agent medication | Associated with control of the sleep-wake cycle. |
Ramelteon is used to help patients fall asleep more rapidly who have sleep-onset insomnia | Used for the short-term treatment of insomnia |
Brand Name: Rozerem | Brand Name: N-acetyl-5-methoxytryptamine |
Ramelteon (Rozerem) is a type 1 and type 2 agonist of the highly selective melatonin receptor 1,2, unlike non-prescription melatonin, which is not selective for all three melatonin receptors.
It acts by stimulating the brain's receptors for melatonin. Melatonin and its receptors regulate the body's circadian rhythm, which regulates the sleep/wake cycle. Ramelteon is not addictive, and it is not a controlled substance, unlike many drugs used for treating insomnia.
Some common side effects are swelling of the tongue, difficulty in swallowing or breathing, feeling discomfort in the throat, Nausea, Vomiting, irregular or missed menstrual periods, milky discharge from the nipples, decreased sexual desire, fertility problems, drowsiness or tiredness, dizziness.
It may or may not cause you to weight gain, depends on your body.
In the elderly, nonbenzodiazepines are safer and better tolerated than tricyclic antidepressants, antihistamines, and benzodiazepines, such as zolpidem, eszopiclone, zaleplon, and ramelteon. Only after sleep hygiene is discussed, however, should pharmacotherapy be recommended.
Even though GABA is not mediated by melatonin agonists, it is suggested that melatonin and ramelteon should not be mixed with alcohol. Alcohol may decrease the sleep effectiveness of melatonin and, when combined with ramelteon, may have additive CNS effects and increase the risk of sleep-related complex behaviors.
Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.
Click here to request a callback!