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What is Ramipril?

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor sold under the brand Altace, among others. It is primarily used to treat high blood pressure (hypertension), heart failure, and diabetic kidney disease. Additionally, Ramipril is used to prevent cardiovascular disease in high-risk individuals. It is often considered a reasonable initial treatment for high blood pressure.

Uses of Ramipril

  • Hypertension: Helps in lowering high blood pressure, thereby reducing the risk of stroke, heart attacks, and kidney problems.
  • Post-Heart Attack: Improves survival rates following a heart attack.
  • Cardiovascular Disease Prevention: Used in high-risk patients, such as those with heart disease or diabetes, to prevent heart attacks and strokes.
  • Heart Failure: Treats heart failure in patients who have recently had a heart attack.

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How To Use Ramipril

  • Administration:
    • Take orally with or without food as directed by your doctor, usually once or twice a day.
    • If taking the capsule form, swallow whole or open the capsule and mix the contents with a cool applesauce or juice.
  • Dosage:
    • The dosage is based on your medical condition and response to treatment.
    • Start with a low dose and gradually increase as directed by your doctor.
  • Regular Use:
    • Use consistently to get the most benefit.
    • Take at the same time each day to help remember.
    • Continue taking it even if you feel well.
  • Monitoring:
    • It may take several weeks to feel the full benefit.
    • Inform your doctor if your condition does not improve or worsens.

Side Effects of Ramipril

Common Side Effects:

  • Blurred vision
  • Confusion
  • Dizziness
  • Faintness
  • Lightheadedness (especially when getting up suddenly)
  • Sweating
  • Unusual tiredness or weakness

Serious Side Effects:

  • Chest pain or discomfort
  • Cold sweats
  • Decrease in urine output
  • Diarrhea
  • Fast or irregular heartbeat
  • Shortness of breath
  • Seizures
  • Cough
  • Nausea or vomiting

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Precautions

  • Allergies: Inform your doctor if you are allergic to Ramipril or other ACE inhibitors.
  • Medical History: Discuss any history of angioedema, dialysis, high blood potassium levels, or other relevant conditions.
  • Dizziness: This medication may cause dizziness; avoid alcohol and be cautious with activities requiring alertness.
  • Dehydration: Ensure adequate hydration, especially during excessive sweating, diarrhea, or vomiting.
  • Potassium Levels: This medication may increase potassium levels; consult your doctor before using potassium supplements or salt substitutes.
  • Older Adults: They may be more sensitive to side effects like dizziness and increased potassium levels.
  • Pregnancy and Breastfeeding: Not recommended during pregnancy due to potential harm to the unborn child. Consult your doctor before breastfeeding.

Interactions

  • Other Medications: Inform your doctor about all other medications, especially those that may increase blood pressure or worsen heart failure (such as NSAIDs, cough and cold products).
  • Allergy Injections: A serious reaction may occur if you are taking Ramipril and receive an allergy injection for bee/wasp stings.

Ramipril Vs Enalapril

Ramipril

 Enalapril

Brand name: Altace

 Brand name: Vasotec

Formula: C23H32N2O5

 Formula: C20H28N2O5

Molar mass: 416.511 g/mol

 Molar mass: 376.4467 g/mol

Uses: Treats high blood pressure, heart failure, diabetic kidney disease, and prevents cardiovascular disease in high-risk patients

 Uses: Treats high blood pressure, heart failure, and diabetic kidney disease

Administration: Oral

 Administration: Oral or intravenous

Citations

Ramipril
Uses Side Effects Precautions Frequently Asked Questions
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Frequently Asked Questions

1. Why is ramipril used for?

Ramipril is used for the treatment of high blood pressure hypertension. Lowering high blood pressure helps prevent stroke, heart attack, and kidney problems. Ramipril is also used to improve survival after a heart attack. It may also be used in high-risk patients (such as those with heart disease/diabetes) to help prevent strokes and heart attacks. This medicine may also be used to treat heart failure in patients who have recently had a heart attack. Ramipril is known as an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily.

2. What does ramipril do to the body?

Ramipril is an inhibitor of the angiotensin-converting enzyme- ACE. It works by blocking a substance in the body that tightens the blood vessels. As a result of this, ramipril relaxes the blood vessels. This reduces blood pressure and increases the supply of blood and oxygen to the heart.

3. What are the side effects of taking ramipril?

Ramipril side effects are as follows:

4. What foods should be avoided when taking ramipril?

It is recommended that you avoid moderately high or high potassium dietary intake if you are taking ramipril. This may cause high levels of potassium in your blood. Do not use salt substitutes or potassium supplements while taking ramipril unless told to do so by your doctor.

5. Does ramipril make you tired?

Headache, dizziness, and tiredness. Dry cough that usually resolves upon discontinuation of therapy. This side effect is common to all inhibitors of ACE. Occasionally, ramipril may cause excessive lowering of blood pressure, but the risk is higher for diuretic patients or those who are sodium-depleted or dehydrated.

6. What time should ramipril be taken?

Ramipril helps lower blood pressure, making it easier for your heart to pump blood around your body. The first dose of ramipril may make you feel dizzy, so it's best to take it at bedtime. You can take ramipril at any time of the day after that.

7. Can ramipril cause anxiety?

Symptoms of anxiety: Patients who are known to have anxiety or tremor should be monitored for these symptoms for at least a few weeks when starting ramipril.

8. How long does ramipril stay in your system?

After multiple doses of ramipril once daily, the effective half-life of ramiprilat concentrations was 13-17 hours for doses of 5-10 mg and longer for lower doses of 1.25-2.5 mg.

9. What is ramipril 5 mg used for?

Ramipril is used for the treatment of high blood pressure (hypertension). Lowering high blood pressure helps in preventing stroke, heart attacks, and kidney problems. Ramipril is also used to improve survival following a heart attack.

10. Can ramipril cause muscle pain?

The most common side effects of ramipril (seen in between 1 in 10 and 1 in 100 people) include headache, dizziness, tick cough, sinus inflammation, shortness of breath, stomach or intestine upset, rash, cramping or muscle pain, low blood pressure or fainting, chest pain and tiredness.

Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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