What is Remdesivir?

Remdesivir is an antiviral drug. It's the first medicine to get approved by the FDA (Food and Drug Administration). It helps to fight with SARS-CoV 2, the virus that causes COVID-19. Preliminary data has shown that patients with advanced COVID-19 and lung problems recover faster after receiving Remdesivir.


Remdesivir Uses

  • Before the approval of FDA and emergency use authorization, Remdesivir was considered as an investigational drug. It was not used for the treatment of any specific conditions, but the medicine was used for the potential treatment of various diseases.
  • At first, This was used for the treatment of Hepatitis. Later in 2014, it was studied as the possible treatment of Ebola Virus. 
  • Researchers have found that this is effective against Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) but the research was conducted in test tubes and on animals, not in humans.

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Remdesivir Side Effects:

Some of the common side effects of remdesivir are:

If you have any of these serious symptoms immediately contact your doctor for further assistance. In any case, due to Remdesivir if you get any kind of reactions in your body try avoiding it. A doctor advised you to take the medicines by seeing your problems and the benefits of this medicine are greater than the side effects.


Precautions

  • Before taking Remdesivir talk to your doctor if you're allergic to any kind of medications. 
  • Talk to your doctor if you're taking any kind of prescription or none to prescribe medicines, vitamins, nutritional supplements and any kind of herbal products.
  • Talk to your doctor if you're having liver or kidney disease.
  • Before taking tell your doctor if you're pregnant or planning for pregnancy.

Remdesivir Dosage

  • Remdesivir comes in the form of solution (liquid) and powder to be mixed with the liquid and infused into the vein by a doctor or nurse in the hospitals. It is given once in a day for 5 to 10 days. The treatment length depends on how long your body takes to respond to the medications.
  • The drug helps in preventing the production of a particular enzyme that is necessary for the virus for replicating itself. Once this is done the virus will no longer be able to spread within the body.
  • Some research has shown that patients who have moderate COVID-19 receive Remdesivir and their symptoms improve very quickly. The drug has also helped in shortening the stay of patients in the hospital.

Missed Dose:

Missing one or two-dose of Remdesivir won't show any effect on your body. The skipped dose causes no problem. But with some medication, it won't work if you don't take the dosage on time. If you miss a dose some sudden chemical change may affect your body. In some cases, your doctor would advise you to take the prescribed medicine as soon as possible if you have missed the dose.

Overdose:

Overdose of a drug can be accidental. If you have taken more than the prescribed Remdesivir tablets there is a chance of getting a harmful effect on your body's functions. Overdose of a medicine can lead to some medical emergency.


Warning for Serious Health Conditions:

Pregnancy

Research has shown that Remdesivir medications are safe during pregnancy but pregnant women have largely been excluded from the clinical trials for COVID-19 treatment options.

Breastfeeding

Remdesivir is given through injection, so infants will not likely absorb clinically important amounts of drug from milk.


Storage

Direct contact with heat, air and light may damage your medicines. The exposure of medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children's reach.

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Recommended Dosage & Dosage in Pediatric Patients

Body Weight Loading Dose (Day 1) Maintenance Dose (Day 2)
3.5 kg – less than 40 kg . 5 mg/kg 2.5 mg/kg
40 kg and higher 200 mg 100 mg

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Frequently Asked Questions

1. What is the drug remdesivir used for?

Remdesivir is an antiviral medication used to treat COVID-19 in hospitalized patients. It is particularly used for those with severe symptoms who require supplemental oxygen.

2. Is remdesivir a high-risk medication?

Remdesivir can have serious side effects, but it is not generally classified as a high-risk medication. It should be used under medical supervision, particularly because it can cause liver and kidney problems.

3. Is remdesivir still approved for COVID?

Yes, remdesivir is still approved for the treatment of COVID-19. The U.S. Food and Drug Administration (FDA) granted it full approval for certain patients in October 2020.

4. Does remdesivir cause organ failure?

Remdesivir can cause adverse effects on the liver and kidneys, which could lead to organ failure in severe cases. Close monitoring of liver and kidney function is required during treatment.

5. Is remdesivir a steroid or antibiotic?

Remdesivir is neither a steroid nor an antibiotic. It is an antiviral medication designed to inhibit the replication of the virus causing COVID-19.

6. Who should not take remdesivir?

Remdesivir should not be taken by individuals who have a known hypersensitivity to the drug or its components. It should also be used with caution in patients with significant liver or kidney impairment.

7. How quickly does remdesivir work?

The effectiveness of remdesivir can vary, but clinical trials have shown that it can reduce the time to recovery by about 5 to 10 days in hospitalized COVID-19 patients.

8. Does remdesivir slow heart rate?

There is no common evidence to suggest that remdesivir significantly affects heart rate. However, like any medication, it can have side effects, and patients should be monitored for any cardiovascular effects.

9. What is the success rate of remdesivir?

The success rate of remdesivir in treating COVID-19 varies. Clinical trials have shown that it can reduce the recovery time and improve outcomes in some patients, particularly those with moderate to severe disease. Its effectiveness is less clear in critically ill patients requiring mechanical ventilation.

10. Does remdesivir cause diabetes?

There is no direct evidence to suggest that remdesivir causes diabetes. However, it can have side effects that may affect various organ systems, so patients with preexisting conditions should be closely monitored.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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