What is Saxagliptin?

Saxagliptin, a medication used in adults with type 2 diabetes, helps improve blood sugar control when combined with diet and exercise. It works by increasing levels of incretins, natural substances that enhance insulin release after meals and reduce liver sugar production.

Saxagliptin Uses

Saxagliptin is prescribed to manage high blood sugar levels in type 2 diabetes patients. Effective control can prevent complications such as kidney damage, blindness, nerve issues, limb loss, and sexual dysfunction. It also reduces the risk of heart attack or stroke.

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How to Take Saxagliptin

Take orally, with or without food, once daily as directed by your doctor.
Do not break the tablet before consumption unless specified.
Dosage depends on medical condition, response to treatment, and concurrent medications.
Consistency in timing helps maximize benefits.

Saxagliptin Side Effects

Common:

Anxiety
Blurred vision
Dizziness
Nausea
Weight changes

Serious (Seek Medical Attention):

Difficulty breathing
Seizures
Unexplained weight gain or loss

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Precautions

Inform your doctor of allergies to saxagliptin or other medications.
Disclose medical history, including kidney disease and heart failure.
Manage low or high blood sugar symptoms cautiously, especially during stress.
Avoid alcohol consumption, which can increase pancreatitis and low blood sugar risks.
Not recommended during pregnancy; consult your doctor if breastfeeding.

Interactions

Beta-blockers may alleviate rapid heartbeat during low blood sugar.
Monitor blood sugar levels closely when starting or stopping medications.

Missed Dose

If a dose is missed, skip it and resume regular schedule. Do not double up.

Overdose

Accidental overdose may cause severe complications; seek immediate medical help.

Storage

Keep away from heat, light, and moisture. Store in a secure place, out of children’s reach.

Saxagliptin vs Sitagliptin

Saxagliptin and Sitagliptin both belong to the DPP-4 inhibitor class, used to manage type 2 diabetes by enhancing insulin levels after meals. They differ slightly in their mechanism of action and specific clinical applications.

Citations

Saxagliptin Effects of saxagliptin and sitagliptin on glycaemic control and pancreatic β-cell mass in a streptozotocin-induced mouse model of type 2 diabetes

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Frequently Asked Questions

1. What is saxagliptin used for?

Saxagliptin is used in type 2 diabetes to lower blood sugar levels when diet and exercise alone are not sufficient.

2. How does saxagliptin work?

Saxagliptin increases incretin levels, which help control blood sugar by increasing insulin release after meals and reducing liver sugar production.

3. Does saxagliptin cause weight gain?

Saxagliptin may or may not cause weight gain, depending on individual cases.

4. What is the benefit of using Saxagliptin with insulin?

When combined with insulin, saxagliptin can lower the insulin dose needed and reduce the risk of hypoglycemia.

5. Does Saxagliptin cause weight loss?

No, saxagliptin does not cause weight loss. However, weight gain may occur when combined with other diabetes medications.

6. Is it beneficial to use Saxagliptin with glipizide?

Yes, combining Saxagliptin with glipizide can help better control blood sugar levels as they work differently to lower blood sugar.

7. Can Saxagliptin be used with other diabetes medicines?

Yes, Saxagliptin can be used alone or in combination with other diabetes medications, alongside a healthy diet and exercise.

8. Can the use of Saxagliptin cause hypoglycemia?

When used alone, saxagliptin does not usually cause hypoglycemia. However, when combined with insulin or sulfonylureas, it may lead to low blood sugar.

9. How long does it take for saxagliptin to start working?

Saxagliptin starts to work within 4 to 5 days, but its full effects on lowering blood sugar may take some time.

Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.