Selegiline is a monoamine oxidase type B (MAO-B) inhibitor used to manage symptoms of Parkinson's disease. It helps by preventing the breakdown of dopamine in the brain, which is crucial for controlling movement.
Selegiline Uses
Parkinson's Disease : It is prescribed to alleviate movement disorders associated with Parkinson's disease. While it doesn't cure Parkinson's, it can improve symptoms such as tremors, muscle weakness,
and fluctuations in movement control ("on-off" phenomena). It is often used in combination with other Parkinson's medications like carbidopa-levodopa.
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Inform your doctor if you are allergic to selegiline or any related medications.
Discuss any medical history, especially adrenal gland tumors, cerebrovascular disease, heart problems, bleeding disorders, headaches, or peptic ulcers.
Avoid using selegiline with certain medications and substances due to potential interactions.
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Oral Tablet : Usually taken twice daily with breakfast and lunch.
Orally Disintegrating Tablet : Taken once daily before breakfast. Place the tablet on the tongue and allow it to dissolve without swallowing. Avoid eating or drinking for 5 minutes before and after taking the tablet.
Dosage
Oral Tablet : Typically started at 5 mg twice daily, with a maximum daily dose of 10 mg.
Orally Disintegrating Tablet : Initiated at 1.25 mg daily for at least 6 weeks, with potential to increase to 2.5 mg daily if needed.
Missed Dose
Missing a dose generally has no significant effects, but follow your doctor's instructions. Do not double up on doses.
Overdose
Accidental overdose can be serious. Seek medical attention immediately if you suspect an overdose.
Interactions
Selegiline can interact with various medications, including antidepressants, other MAO inhibitors, appetite suppressants, ADHD medications, and others. Always inform your doctor about all medications you are taking.
Storage
Store selegiline at room temperature, away from heat, light, and moisture. Keep it out of reach of children.
Selegiline is used in people taking the combination of levodopa and carbidopa to help control the symptoms of Parkinson's disease.
2. Is selegiline a dopamine agonist?
No, selegiline is not a dopamine agonist. It is a selective monoamine oxidase B (MAO-B) inhibitor.
3. Is selegiline a stimulant?
No, selegiline is not considered a stimulant. Its potential for abuse is very low.
4. Why is selegiline prescribed for Parkinson's disease?
Selegiline is prescribed for Parkinson's disease to increase dopamine levels in the brain, which helps to better control movement and other symptoms.
5. How long does selegiline take to work?
The onset of action of selegiline can vary, typically showing improvement in Parkinson's symptoms within several weeks to months of starting treatment.
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