What is Silymarin?

Silymarin (Milk thistle) is a flowering herb related to the family of daisies and ragweeds. It is native to countries in the Mediterranean. Silymarin is a standardized milk thistle seed extract containing a mixture of Flavonolignans (Silybum Marianum). This medication is a herbal supplement that allows the liver function to be detoxified and preserved.


What are the Uses of Silymarin?

The medication is used for the treatment of Chronic Liver Disease and Cirrhosis of the liver. Silymarin is an active concept obtained from milk thistle seed (Silybum marianum). It could protect liver cells from chemicals and drugs that are harmful. Apparently, it also has an antioxidant and anti-inflammatory impact. Milk thistle plant extract may improve the estrogen effects.


What are the Side Effects of Silymarin?

Some of the common side effects of Silymarin are:

Some of the serious side effects of Silymarin are:

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What are the Precautions of Silymarin?

Before using the Silymarin talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other serious problems. Before using Silymarin talk with your doctor if you are having any medical history such as:

How to take Silymarin?

The best doses of Silymarin are not yet established for any conditions. The consistency and active ingredients in supplements can differ widely from manufacturer to manufacturer. This makes the establishment of a regular dose very difficult. Ask for advice from your doctor.

For dyspepsia and biliary system disorders, one source suggests daily doses of 12 to 15 g of dried fruit, while an extract containing 200 to 400 mg/day of silymarin is considered effective in various liver disorders.


What to Do If You Miss a Dose of Silymarin?

If a dose of this drug is missing, take it as soon as possible. If it is almost time for your next dose, however, skip the skipped dose and go back to your routine for daily dosing. Do not use double doses.

What to Do for a Suspected Overdose?

Overdose of a drug can be accidental. If you have taken more than the prescribed Silymarin tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.


What are the Interactions of Silymarin?

Silymarin can decrease how quickly those medications break down in the liver. The effects and side effects of some medications can be increased by taking silymarin along with some medications that are broken down by the liver. Talk to your healthcare provider before taking silymarin if you take any medications that are modified by the liver.

Some drugs that are modified by the liver include:

  • Amitriptyline (Elavil)
  • Diazepam (Valium)
  • Zileuton (Zyflo)
  • Celecoxib (Celebrex)
  • Diclofenac (Voltaren)
  • Fluvastatin (Lescol)
  • Glipizide (Glucotrol)
  • Ibuprofen (Advil, Motrin)
  • Irbesartan (Avapro)
  • Losartan (Cozaar)
  • Phenytoin (Dilantin)
  • Piroxicam (Feldene)
  • Tamoxifen (Nolvadex)
  • Tolbutamide (Tolinase)
  • Torsemide (Demadex)

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How to Store Silymarin?

Store it away from light and moisture at room temperature between 68-77º F (20-25º C). Brief storage is allowed between 59-86º F (15-30º C). Keep all medication away from pets and children.

However, if you experience any of the following signs of a serious allergic reaction, stop taking Silymarin acid and seek medical attention immediately: rash/blisters, itching, swelling, extreme dizziness and difficulty breathing.


Silymarin vs Lecithin

Silymarin Lecithin
Silymarin (Milk thistle) is a flowering herb related to the family of daisies and ragweeds. It is native to countries in the Mediterranean. Lecithin supplements can also be used during breast-feeding to treat elevated cholesterol and digestive disorders and to avoid clogged milk ducts.
The medication is used for the treatment of Chronic Liver Disease and Cirrhosis of the liver. Silymarin is an active concept obtained from milk thistle seed (Silybum marianum). Lecithin is used to treat memory problems such as Alzheimer's disease and dementia. It is also used to treat gallbladder disease, liver disease, depression of some forms, high cholesterol, anxiety, and eczema, a skin disease.
Some of the common side effects of Silymarin are:
  • Nausea
  • Diarrhea
  • Intestinal gas
  • Fullness or pain in the stomach
  • Loss of appetite
Some of the common side effects of Lecithin are:
  • Back pain
  • Bloating
  • Diarrhea
  • Itching
  • Loss of appetite

Citations

The Use of Silymarin in the Treatment of Liver Diseases Silymarin
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Frequently Asked Questions

1. What is silymarin used for?

Silymarin, an active extract from milk thistle, is primarily used to support liver health, treat liver diseases, and protect the liver from toxins and inflammation.

2. Does silymarin lower SGPT?

Silymarin has been shown to help lower elevated liver enzymes, including SGPT (Serum Glutamic Pyruvic Transaminase), indicating its potential benefit in improving liver function.

3. Is milk thistle the same as silymarin?

Yes, silymarin is an extract derived from the seeds of the milk thistle plant and is considered the active component responsible for its therapeutic effects.

4. Can silymarin cause itching?

Although rare, some individuals may experience allergic reactions to silymarin, including itching. If you experience itching or other allergic symptoms, discontinue use and consult a healthcare provider.

5. Is silymarin safe for kidneys?

Silymarin is generally considered safe for the kidneys and may even offer protective benefits. However, those with kidney conditions should consult their healthcare provider before using it.

6. How long can silymarin be taken?

The duration of silymarin use depends on the individual's condition and the advice of a healthcare provider. It can be taken long-term for chronic liver conditions but should be monitored by a healthcare professional.

7. Who should not take silymarin?

Individuals who are allergic to plants in the Asteraceae/Compositae family, pregnant or breastfeeding women, and those with hormone-sensitive conditions should avoid silymarin unless advised by a healthcare provider.

8. Can silymarin increase bilirubin?

Silymarin is not typically associated with increasing bilirubin levels. In fact, it is often used to help manage liver conditions that may result in elevated bilirubin.

9. Can I take silymarin without food?

Silymarin can be taken with or without food, but taking it with food may enhance absorption and reduce the risk of gastrointestinal discomfort.

10. Can you use silymarin at night?

Yes, silymarin can be taken at night. The timing of the dose is flexible and can be adjusted based on personal preference and the guidance of a healthcare provider.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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