What is Stelara?

Q: What are the side effects of Humira?

Headache, upper respiratory infections, fatigue, redness at the injection site, vaginal yeast infections.

Stelara is an immunosuppressant that reduces the effects of a chemical compound in the body that triggers inflammation. It is used to treat:

Plaque psoriasis in adults and children aged 6 and older
Psoriatic arthritis in adults, often in combination with methotrexate
Moderately to severely active Crohn's disease in adults after other drugs have failed
Moderately to severely active ulcerative colitis in adults

Uses of Stelara

Stelara is used for:

Moderate to Severe Psoriasis: In adults and children who may benefit from phototherapy (light therapy) or systemic therapy (drugs taken orally or by injection).
Psoriatic Arthritis: In adults, alone or in combination with methotrexate.
Crohn’s Disease : In adults who have not responded to other treatments or who experienced serious side effects from other treatments.
Ulcerative Colitis: In adults with moderately to severely active disease.

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Side Effects of Stelara

Common side effects include:

Headache
Upper respiratory infections
Fatigue
Redness at the injection site
Vaginal yeast infections
Itchy skin
Urinary tract infection
Vomiting

Serious side effects may include:

Pneumonia
Appendicitis
Cholecystitis
Osteomyelitis
Gastroenteritis
Diverticulitis
Cellulitis
Tuberculosis

How to Take Stelara

Before Starting: A TB skin test is necessary to rule out latent TB.
Dosage: Determined by weight, medical condition, and treatment response. Available as a prefilled syringe or single-dose vial, with common dosages being 45 mg or 90 mg.
Administration: Injected subcutaneously in the upper arms, legs, stomach, or buttocks. Can be self-administered after proper training or given by a healthcare provider.
Missed Dose: Contact your doctor if you miss a dose. Do not take extra doses to make up for missed ones.

Overdose

If an overdose is suspected, seek immediate medical attention. Overdose can lead to serious health issues.

Warnings

Pregnancy: Not recommended for use during pregnancy. Consult your doctor if you are pregnant or planning to become pregnant.
Breastfeeding: Not recommended during breastfeeding as it may pass into breast milk. Consult your doctor for alternatives.

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Storage

Store Stelara at room temperature between 68°F and 77°F (20°C and 25°C). Keep it away from heat, light, and moisture, and out of reach of children.

Stelara vs Humira

Stelara	Humira
Immunosuppressant that reduces the effects of a chemical compound in the body that triggers inflammation.	Tumor necrosis factor (TNF) inhibitor that decreases the inflammatory effects of a substance in the body.
Used for moderate to severe psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis.	Used to relieve pain and swelling associated with various forms of arthritis.
Common side effects include headache, upper respiratory infections, fatigue, redness at the injection site, vaginal yeast infections.	Common side effects include swelling at the injection site, upper respiratory infection, headache, rash.

Citations

Stelara safe after IL-12 antibody dispute | Nature Reviews Drug Discovery

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Frequently Asked Questions

1. What is Stelara used for?

Stelara is used for the treatment of moderate to severe psoriasis in adults and children. It's safe to use for people who may benefit from phototherapy (light therapy) or systemic therapy (drugs taken by mouth or through an injection).

2. How does Stelara work for Crohn's disease?

Stelara is a monoclonal antibody that inhibits interleukin-12 and interleukin-23, two inflammatory proteins. The medication was originally approved for the treatment of psoriasis, but it is now approved for the treatment of Crohn's disease, a gastrointestinal inflammatory disease that lasts for years.

3. How long can you stay on Stelara?

Stelara is capable of operating rapidly. Patients who respond to the medication normally do so within six weeks, but some may take more time. Stelara can be used indefinitely as long as it continues to function and the side effects are held to a minimum.

4. Is Stelara better than Humira?

Stelara (Ustekinumab) treats two forms of psoriasis. Because of the injection, it can be a hassle at first, but after the first two doses, you just need to take it every 12 weeks. In all of its approved indications, Humira (adalimumab) is effective at reducing symptoms.

5. What are the side effects of Humira?

Common side effects of Humira include headache, upper respiratory infections, fatigue, redness at the injection site, and vaginal yeast infections.

Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.