Theophylline Overview

Theophylline, also known as 1,3-dimethylxanthine, is a phosphodiesterase inhibiting medication used for the treatment of respiratory disorders such as chronic obstructive pulmonary disease (COPD) and asthma.


Uses of Theophylline

  • Treats lung conditions such as asthma and COPD ( bronchitis, emphysema).
  • Used daily to avoid wheezing and shortness of breath.
  • Belongs to the xanthine family of medicines.
  • Relaxes the muscles around the airways to improve breathing.
  • Reduces lung response to irritants, minimizing time spent at work or school due to breathing issues.

How to Take Theophylline Tablets

  • Take by mouth as directed by your doctor, usually once or twice daily.
  • Follow your doctor's or pharmacist's instructions regarding timing and whether to take with food.
  • Do not crush or chew the capsules or tablets. Swallow them whole.
  • Dosage is based on medical condition, response to treatment, age, weight and other medications.
  • Take the medication regularly at the same time each day for the best effect.
  • Continue taking it even if you feel well.

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Theophylline Side Effects

Common Side Effects:

Severe Side Effects:

Allergic reactions:

  • Rash
  • Itching
  • Swelling (face/tongue/throat)
  • Extreme dizziness
  • Difficulty breathing

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Important Precautions for Theophylline

  • Inform your doctor if you are allergic to theophylline or other xanthine medications (e.g., aminophylline, oxtriphylline, caffeine).
  • Share your medical history, especially if you have stomach/intestinal ulcers, seizures, thyroid disease, heart issues, liver disease, or high blood pressure.
  • Children may be more susceptible to side effects.
  • Use during pregnancy only if absolutely necessary. Monitor blood levels and side effects closely.
  • Consult your doctor before breastfeeding.

Dosage Information

  • Keep a list of all medications you use (prescription, nonprescription, herbal products) and share it with your doctor and pharmacist.
  • Certain drugs can interfere with theophylline (e.g: cimetidine, disulfiram, fluvoxamine, interferon, propranolol).
  • Avoid large amounts of caffeine or alcohol as they can increase side effects.
  • Smoking can reduce the effectiveness of theophylline. Inform your doctor if you smoke or have recently quit.

Missed Dose:

  • Take the missed dose as soon as you remember.
  • Skip the missed dose if it's near the time for your next dose. Do not double the dose.
  • Set reminders to help remember doses. Consult your doctor if you frequently miss doses.

Overdose:

  • Do not take more than the prescribed dose.
  • In case of overdose, seek immediate medical attention. Bring the medication bottle for reference.

Storage:

  • Store at room temperature, away from extreme heat and direct light.
  • Do not freeze.
  • Do not flush medications down the toilet or pour them into drainage.
  • Consult your pharmacist or doctor on how to safely discard the medication.

Other important information:

  • Keep all meetings with your doctor and the laboratory. In order to confirm your reaction to theophylline, your doctor will order some lab tests.
  • Without talking to your doctor, do not move from one brand of theophylline to another.
  • Do not let the medicine be taken by someone else. If you have any questions about refilling your prescription, ask your pharmacist.
  • As well as any products such as vitamins, minerals, or other dietary supplements, it is essential for you to keep a written list of all the prescription and nonprescription (over-the-counter) medicines you are taking. Any time you visit a doctor or if you are an admin, you can carry this list with you.

Theophylline vs Acebrophylline

Theophylline Acebrophylline
Used in treating lung conditions such as asthma and COPD Used in the treatment of Bronchial Asthma, COPD, Bronchitis, Sinusitis
It is 1,3-dimethylxanthine Itraconazole is used for treating fungal infections. It belongs to azole antifungal drugs. It works as stopping the growth of fungi.
Brand name phosphodiesterase inhibiting medication Brand name AB PHYLLINE cap
Available as Generic drug Available as Generic drug

Citations

Theophylline, ID:10.1016/S0140-6736(78)90305-7
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Frequently Asked Questions

1. What is the usual dosage of Theophylline?

The dosage of theophylline varies depending on the individual's medical condition, age, weight, and response to treatment. A typical starting dose for adults is 300 mg daily, divided into several smaller doses, with adjustments made based on blood levels and clinical response. It is crucial to follow your doctor's specific dosage instructions.

2. How should I take Theophylline?

Theophylline is usually taken by mouth, either as a tablet or capsule, once or twice daily. It should be taken at the same time each day to maintain an even level in your blood. Follow your doctor's instructions regarding whether to take it with food or on an empty stomach.

3. Can Theophylline dosage be adjusted?

Yes, your doctor may adjust your theophylline dosage based on your response to the medication and blood test results. Regular monitoring is important to ensure the medication is effective and to minimize the risk of side effects.

4. What is Theophylline injection used for?

Theophylline injection is used in emergency situations to treat severe symptoms of asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions. It is administered when oral forms of the medication are not feasible or when rapid action is needed.

5. What are the benefits of Theophylline injection?

Theophylline injection can quickly relax and open the airways in the lungs, providing rapid relief from severe respiratory symptoms such as wheezing and shortness of breath.

6. How does Theophylline work?

Theophylline works by relaxing the smooth muscles around the airways in the lungs, making it easier to breathe. It is a bronchodilator that helps open up the airways, reducing symptoms of asthma and COPD.

7. What class of drug is Theophylline?

Theophylline belongs to a class of drugs known as xanthines. It is chemically related to caffeine and works by inhibiting the enzyme phosphodiesterase, which leads to an increase in cyclic AMP levels, causing bronchodilation.

8. What other effects does Theophylline have?

In addition to bronchodilation, Theophylline has mild anti-inflammatory effects and can improve diaphragm muscle contractility, which helps enhance breathing in patients with respiratory conditions.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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