What is Vildagliptin?

Vildagliptin is a new oral anti-hyperglycemic (anti-diabetic) tablet from the new dipeptidyl peptidase-4 (DPP-4) inhibitor class. The medication works by preventing DPP-4 from inactivating glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP).

This inhibitory activity leads to a two-fold action in the pancreas islets of Langerhans, where GLP-1 and GIP potentiate insulin secretion by beta cells while suppressing glucagon secretion by alpha cells.


What are Vildagliptin Uses?

Vildagliptin is used for the treatment of Type 2 diabetes mellitus. This is used along with diet and exercise to improve blood sugar control in adults with Type 2 diabetes. The medication is a type of anti-diabetic drug.

Vildagliptin works by causing the pancreas to release more insulin and decreasing the hormones that cause blood sugar levels to rise. As a result, fasting and post-meal sugar levels are reduced.

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What are Vildagliptin Tablet Side Effects?

Some of the common and major side effects of Vildagliptin are:

  • Headache
  • Cough
  • Constipation
  • Sweating
  • Hypoglycaemia
  • Weakness
  • Excessive sweating
  • Heartburn
  • Swelling of face, lips and eyelids

The common side effects don’t need medical attention and will disappear as your body adjusts to the dosage. But if you are facing any serious or rare side effects, then immediately seek medical attention.


Precautions for Using Vildagliptin Drug

The product can contain inactive ingredients that cause serious allergic reactions or other serious problems. Before using Vildagliptin, talk with your doctor if you are allergic to it or have any of the following medical histories: skin allergy, Type I diabetes mellitus, Diabetic Ketoacidosis, or Hepatic Impairment.


    How to Use & Dosage of Vildagliptin?

    Read the manufacturer’s printed information carefully to know about the procedure. It will provide you with more detail about vildagliptin tablets as well as a complete list of the possible side effects that you can encounter as a result of taking them.

    Take vildagliptin exactly as the doctor prescribed. The standard dosage is one 50 mg tablet taken twice a day. But depending on your other medications, you might only need one dose per day. Your doctor will instruct you exactly how many doses to take, and this detail will be printed on the label of the tablet pack to act as a reminder.

    Missed Dose

    As soon as you remember, take the missing dose. If it’s time for the next dose, skip the missed dose. Do not take a double dose to compensate for a missed dose.

    Overdose

    Overdose of this medication can lead to some serious side effects like irregular heartbeat, trouble breathing, severe dizziness and fainting.


    Vildagliptin Drug Warnings for Serious Health Conditions

    Pregnancy

    Pregnant women should avoid taking this drug unless it is appropriate. Before taking this drug, talk to your doctor about all the complications and benefits. Depending on your health condition, your doctor can recommend a safer alternative.

    Breastfeeding

    The medication can pass into the breast milk and can cause some serious side effects to the infants. Avoid taking this medication without consulting your doctor while you are breastfeeding.


    How to Store Vildagliptin Drug

    Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly, the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).


    Vildagliptin Vs Sitagliptin

    Vildagliptin Sitagliptin
    Vildagliptin is a new oral anti-hyperglycemic (anti-diabetic) medication from the new dipeptidyl peptidase-4 (DPP-4) inhibitor class. Sitagliptin is a prescription drug and it is available in the form of an oral tablet.
    The medication is used for the treatment of Type 2 diabetes mellitus. This is used along with diet and exercise to improve blood sugar control in adults with Type 2 diabetes. Sitagliptin tablets can be taken with a proper diet, exercise, and other medication for controlling high blood sugar. The medication is used in people with type 2 diabetes.
    Some of the common and major side effects of Vildagliptin are:
    • Headache
    • Common cold
    • Cough
    • Constipation
    • Dizziness
    Some of the common side effects of Sitagliptin are:
    • Stomach cramp
    • Diarrhea
    • Respiratory infection
    • Headache

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    Frequently Asked Questions

    The medication is used for the treatment of Type 2 diabetes mellitus. This is used along with diet and exercise to improve blood sugar control in adults with Type 2 diabetes. The medication is a type of anti-diabetic drug.

    Vildagliptin is an important and well-tolerated treatment choice for elderly patients with type 2 diabetes. It shows comparable glycemic regulation to metformin but better GI tolerability.

    Vildagliptin is reasonably safe in clinical trials; however, long-term safety evaluations and clinical experience with the effects of DPP4 inhibition are needed. The DPP4 enzyme is found in various tissues and is a substrate for various hormones and peptides in the human body.

    If you’ve been prescribed vildagliptin, take it first thing in the morning. Take the first dose in the morning and the second dose in the evening if you’ve been advised to take two doses every day. Vildagliptin tablets may be taken before, during, or after meals.

    Vildagliptin, the active ingredient in Galvus, is a dipeptidyl-peptidase-4 (DPP-4) inhibitor. It functions by stopping the body from breaking down ‘incretin’ hormones. Following a meal, these hormones are released, stimulating the pancreas to produce insulin.

    Some of the common and major side effects of Vildagliptin are:

    • Headache
    • Common cold
    • Cough
    • Constipation
    • Dizziness
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