Mouth Ulcer: Causes, Symptoms, and Treatment Options 

A mouth ulcer, or canker sore, is a painful lesion that forms on the mucous membrane inside the mouth. Various factors like stress, injury, or certain foods can cause them. 

Treatment involves topical medications to relieve pain and promote healing. Maintaining good oral hygiene can help prevent them.

A mouth ulcer is a lesion that can form on the inner tissues of your mouth. These lesions typically present as red, yellow, or white spots, and you may have one or multiple sores.

Mouth ulcers can develop on:

  • Gums
  • Tongue
  • Roof of the mouth (palate)
  • Inner cheeks
  • Inner lips

These ulcers are frequently painful and may cause discomfort while eating, drinking, and speaking.

Types of Mouth Ulcers

Here are the common types of mouth ulcers:

  • Canker Sores (Aphthous Stomatitis): Small, round or oval sores that appear inside the mouth, often on the cheeks, gums, or tongue. They can be painful but are not contagious.
  • Cold Sores (Herpes Simplex Virus): Blisters caused by the herpes simplex virus, typically on the lips or around the mouth. They can be contagious.
  • Traumatic Ulcers: Caused by injury or irritation, such as from biting the inside of the cheek or a sharp tooth, braces, or dental work.
  • Hand, Foot, and Mouth Disease: A viral infection that can cause ulcers in the mouth, usually affecting children, accompanied by rash on hands and feet.
  • Leukoplakia: White patches that can sometimes turn into ulcers, often associated with smoking or other irritants.
  • Oral Thrush (Candidiasis): Fungal infection caused by Candida yeast, leading to painful white patches or ulcers in the mouth.

Each type may vary in severity and mouth ulcer treatment methods.

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Mouth Ulcer Symptoms

Here are common symptoms of mouth ulcers:

  • Pain or Tenderness: The ulcer can be painful, especially when eating, drinking, or talking.
  • Red or White Sore: A small round or oval sore with a red border and a white or yellowish center.
  • Swelling: The affected area around the ulcer may appear swollen.
  • Burning or Tingling Sensation: You may feel a slight burning or tingling sensation before the ulcer appears.
  • Difficulty Eating or Drinking: The ulcer may make it difficult to eat or drink, particularly hot, spicy, or acidic foods.
  • Bleeding: The ulcer may bleed if it gets irritated, such as from brushing teeth or eating rough foods.

These symptoms are common in canker sores and other types of mouth ulcers.

Symptoms of Minor, Major Herpetiform Ulcers 

Minor mouth ulcers

  • They are usually small
  • They are oval with a red border
  • Heals without scarring in one to two weeks

Major mouth ulcers

Major mouth ulcers are less common and:

  • They are larger and deeper than minor canker sores
  • They are usually round with sharp edges but may have ragged edges when they are very large
  • It can be extremely painful
  • It can take up to six weeks to heal and can leave extensive scars

Herpetiform mouth ulcers

Herpetiform mouth ulcers are rare and usually develop later in life, but they are not caused by an infection with the herpes virus. These mouth ulcers:

  • Are exactly sized
  • They often occur in groups of 10 to 100 sores but can merge into one large ulcer.
  • Have ragged edges
  • Heals without scarring in one to two weeks

Mouth Ulcers Causes

Mouth ulcers, also known as canker sores, can be caused by several factors. Here are the common causes:

  • Injury or Trauma:
    • Biting the inside of the cheek or lip.
    • Brushing too hard or using a hard-bristled toothbrush.
    • Accidental injury from dental appliances like braces or dentures.
  • Stress:
  • Hormonal Changes:
    • Hormonal fluctuations during menstruation, pregnancy, or menopause can lead to mouth ulcers.
  • Nutritional Deficiencies:
    • Lack of certain vitamins and minerals, especially vitamin B12, iron, and folic acid, can contribute to mouth ulcers.
  • Food Sensitivities:
    • Acidic foods like citrus fruits, spicy foods, and chocolate can irritate the mouth and lead to ulcers.
    • Allergies to certain foods can also cause ulcers.
  • Infections:
    • Viral infections, such as the herpes simplex virus, can cause painful mouth ulcers.
    • Bacterial infections in the mouth can also contribute.
  • Autoimmune Conditions:
    • Conditions like Crohn’s disease, celiac disease, and lupus can cause recurring mouth ulcers as part of their symptoms.
  • Medications:
    • Certain medications, such as those for chemotherapy, pain relievers, or nonsteroidal anti-inflammatory drugs (NSAIDs), can cause mouth ulcers as a side effect.
  • Genetics:
    • A family history of mouth ulcers can increase the likelihood of developing them.
  • Underlying Health Conditions:
    • Conditions like HIV/AIDS, gastrointestinal diseases, and other chronic illnesses can contribute to the development of mouth ulcers.

Health conditions associated with mouth ulcers

  • Autoimmune Diseases
  • Gastrointestinal Disorders
  • Viral Infections
  • Nutritional Deficiencies
  • Hormonal Changes
  • Stress and Emotional Factors
  • Chronic Illnesses
  • Medications
  • Genetic Predisposition
  • Other Conditions

Mouth Ulcer Diagnosis and Tests

  • Physical Examination: The doctor will visually inspect the ulcer and surrounding tissue to determine its size, appearance, and location.
  • Medical History: The doctor may ask about your symptoms, frequency of ulcers, and any triggers such as diet, stress, or medications.
  • Blood Tests: Blood tests may be conducted to check for underlying conditions like nutritional deficiencies (e.g., vitamin B12 or iron) or autoimmune diseases.
  • Biopsy: In rare cases, if the ulcer doesn't heal or there's concern about more serious conditions, a biopsy (small tissue sample) may be taken for examination.
  • Other Tests: If necessary, the doctor might suggest tests to rule out conditions like gastrointestinal disorders, viral infections, or immune system diseases.

Treatment for Mouth Ulcer

Treatment for mouth cancer typically includes:

  • Surgery: Removal of cancerous tissue.
  • Radiation Therapy: Targets and destroys cancer cells.
  • Chemotherapy: Uses drugs to kill or inhibit cancer cell growth.
  • Targeted Therapy: Targets specific cancer cell mechanisms.
  • Immunotherapy: Stimulates the immune system to attack cancer cells.
  • Palliative Care: Focuses on pain management and improving quality of life.

Mouth Ulcer Medicine

  • Mouth ulcer gel: Topical gels like benzocaine offer pain relief and reduce inflammation.
  • Prescription Medications: Stronger options such as corticosteroids and antibiotics for infection and inflammation control.
  • Antiseptic Mouthwashes: Mouthwashes with chlorhexidine or hydrogen peroxide help reduce bacteria and prevent infections.
  • Nutritional Supplements: Vitamins like B12, folate, and iron may be recommended for deficiencies contributing to mouth ulcers.
  • Alternative Treatments: Coconut oil, aloe vera gel, mouth ulcer creams or honey may offer soothing and anti-inflammatory benefits.

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When to Visit a Doctor?

People who have mouth ulcers can often have a hard time knowing when to see a doctor. However, there are some situations in which a person should see a doctor as soon as possible. Some of these circumstances include:

  • the appearance of a non-painful ulcer in one or more areas of the mouth
  • unusual ulcers that appear in a new place in the mouth
  • ulcers that are spreading
  • ulcers that last more than 3 weeks

Others may want to seek medical care or treatment for their ulcers if:

  • are particularly painful or large
  • fever appears
  • develop after starting a new medicine
  • secondary bacterial infections

Home Remedies of Mouth Ulcers

  • Rinse with salt water.
  • Apply honey
  • Use aloe vera
  • Coconut oil pulling
  • Avoid spicy and acidic foods
  • Apply ice
  • Over-the-counter pain relief
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Frequently Asked Questions

Can mouth ulcers be contagious?

No, they're not contagious. They're often caused by minor injuries, stress, or certain foods.

How long do mouth ulcers usually last?

Typically, they heal within 1-2 weeks. But if they persist for more than three weeks, it's wise to see a doctor.

Can mouth ulcers be a sign of something serious?

While usually harmless, they can sometimes indicate an underlying health issue. If you get frequent or unusually large ulcers, it's best to consult a healthcare professional.

How can I prevent mouth ulcers?

Maintaining good oral hygiene, managing stress, and avoiding trigger foods like citrus fruits can reduce your risk. Also, ensure you're getting enough vitamins and minerals in your diet to support oral health.

What are the reasons for mouth ulcers?

Mouth ulcers can be caused by factors like stress, injury, viral infections (like cold sores), vitamin deficiencies (B12, folic acid), certain medications, or underlying health conditions such as Crohn's disease.

How can I cure mouth ulcers?

Mouth ulcers can be treated with over-the-counter topical creams, mouth rinses, and pain relievers. Avoid spicy foods, maintain good oral hygiene, and try saltwater rinses or honey to promote healing.

What is a mouthwash for mouth ulcers?

Mouthwash for mouth ulcers typically contains ingredients like saline, hydrogen peroxide, or antimicrobial agents to reduce pain, prevent infection, and promote healing. Over-the-counter options like Listerine or salt water rinses can help soothe mouth ulcers.

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